Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

Researchers identify 55 lingering effects of COVID-19

As COVID-19 hospitalizations once again soar in a fourth surge more than 18 months after the pandemic started, some patients continue to experience symptoms long after recovering from COVID, according to a Houston Methodist study recently published in Nature's Scientific Reports.

30 Aug 2021

Researchers analyze dynamic changes in chest CT images over 167 days in 11 COVID-19 patients

Announcing a new article publication for Zoonoses journal. In this article the authors Jianqin Liang, Guizeng Liu, Shuzhuang Yu, Yang Yang, Yanchun Li, Hongli Tian, Zhe Chen and Wenping Gong The Eighth Medical Center of PLA General Hospital, Beijing, China and Nanpi County People's Hospital, Hebei, China discuss dynamic changes in chest CT images over 167 days in 11 patients with COVID-19.

28 Aug 2021

Researchers find clues to how lung damage develops in the aftermath of a respiratory infection

The deadliest time in a viral respiratory illness sometimes is actually after the virus is cleared from the body. Destructive processes that are set in motion during an infection crest in the weeks after the virus is defeated, leading to organ damage that can cause chronic illness or even death.

24 Aug 2021

Study suggests a novel therapeutic target to reverse lung fibrosis

Researchers have reversed lung fibrosis in a mouse model of idiopathic pulmonary fibrosis, or IPF, as reported in a study published in the journal Cell Death and Differentiation.

24 Aug 2021

New bioengineered lung model could help scientists to advance research in lung conditions

An interdisciplinary team of researchers from McMaster and SickKids are developing a cutting-edge lung model that can better respond to viruses and drug treatments, giving scientists a tool to advance research in lung conditions like COVID-19, cystic fibrosis and allergens for asthma and air pollution.

18 Aug 2021

Children’s Hospital Colorado helps prove safety and efficacy of CF treatment in younger pediatric patients

Researchers at the Children's Hospital Colorado Breathing Institute, the largest pediatric cystic fibrosis (CF) clinical care center in the U.S., participated in the pivotal international multi-center Phase 3 clinical trial, sponsored by Vertex Pharmaceuticals Incorporated, leading to FDA approval of TRIKAFTA (elexacaftor/tezacaftor/ivacaftor), a highly effective CF treatment, for patients ages 6 through 11 who have at least one copy of the F508del mutation.

17 Aug 2021

Study identifies Foxo1 gene as a potential treatment target for hereditary lymphedema

A University of South Florida preclinical study unexpectedly identified the gene Foxo1 as a potential treatment target for hereditary lymphedema.

10 Aug 2021

Researchers use prime editing to correct cystic fibrosis in cultured human stem cells

Researchers from the group of Hans Clevers (Hubrecht Institute) corrected mutations that cause cystic fibrosis in cultured human stem cells.

9 Aug 2021

Researchers develop a novel process for producing pure RNA

Researchers at the University of Massachusetts Amherst recently unveiled their discovery of a new process for making RNA.

6 Aug 2021

COVID-19 vaccination offers significant protection for solid organ transplant recipients

In a Brief Communication, published July 29, 2021 in the journal Transplant Infectious Disease, a team of physician-scientists at University of California San Diego School of Medicine found that solid organ transplant recipients who were vaccinated experienced an almost 80 percent reduction in the incidence of symptomatic COVID-19 compared to unvaccinated counterparts during the same time.

5 Aug 2021

Feinstein Institutes awarded $2.9 million NIH funding for polygenic embryo selection studies

Genetic testing and selection of embryos generated from in vitro fertilization have given rise to the controversial “designer baby” debate.

4 Aug 2021

New molecular and morphologic insights into chronic rejection after lung transplantation

A study of lung tissue from patients with end-stage bronchiolitis obliterans syndrome (BOS) as a complication of lung transplantation yielded molecular and morphologic insights into the development of chronic rejection.

3 Aug 2021

Serum aldosterone concentrations provide a new measure for risk evaluation in HFpEF patients

Currently, patients with HFpEF have high risk of morbidity and mortality, but there is no effective measure for evaluating the prognosis.

3 Aug 2021

Researchers discover potential biomarker for lung disease in scleroderma patients

Researchers have discovered a protein that may predict disease severity for a lung condition that often proves fatal to patients with scleroderma.

3 Aug 2021

New tool could transform the management of cardiac sarcoidosis patients

Johns Hopkins University scientists have developed a new tool for predicting which patients suffering from a complex inflammatory heart disease are at risk of sudden cardiac arrest.

28 Jul 2021

'Good cholesterol' protects the liver from inflammation and injury, study shows

The body's so-called good cholesterol may be even better than we realize. New research from Washington University School of Medicine in St. Louis suggests that one type of high-density lipoprotein (HDL) has a previously unknown role in protecting the liver from injury.

22 Jul 2021

Fibrosis News and Research

Further Reading

Researchers identify 55 lingering effects of COVID-19

Researchers analyze dynamic changes in chest CT images over 167 days in 11 COVID-19 patients

Researchers find clues to how lung damage develops in the aftermath of a respiratory infection

Study suggests a novel therapeutic target to reverse lung fibrosis

New bioengineered lung model could help scientists to advance research in lung conditions

Children’s Hospital Colorado helps prove safety and efficacy of CF treatment in younger pediatric patients

Study identifies Foxo1 gene as a potential treatment target for hereditary lymphedema

Researchers use prime editing to correct cystic fibrosis in cultured human stem cells

Researchers develop a novel process for producing pure RNA

COVID-19 vaccination offers significant protection for solid organ transplant recipients

Feinstein Institutes awarded $2.9 million NIH funding for polygenic embryo selection studies

New molecular and morphologic insights into chronic rejection after lung transplantation

Serum aldosterone concentrations provide a new measure for risk evaluation in HFpEF patients

Researchers discover potential biomarker for lung disease in scleroderma patients

New tool could transform the management of cardiac sarcoidosis patients

'Good cholesterol' protects the liver from inflammation and injury, study shows

Injecting mice with pulmonary endothelial cells can reverse symptoms of emphysema

Scientists identify gut microbiota dysbiosis as a potential risk factor for long COVID

A path to treat currently untreatable cases of cystic fibrosis is clearly achievable, study suggests

Children of obese mothers at increased risk of fatty liver disease

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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