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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Researchers figure out how nuclear pores duplicate before cells divide

Researchers have long wondered how nuclear pores - the all-important channels that control the flow of information in and out of a cell's nucleus - double in number to prepare for the split to come when a cell divides. Now, for the first time, scientists at the Salk Institute for Biological Studies watched as new funnel-like pore structures formed from scratch, and inserted themselves into the nuclear membrane.

28 Apr 2006

Prefrontal cortex in the brain damaged by both alcoholism and chronic smoking

Alcoholism is commonly associated with chronic smoking, and both alcohol and nicotine are believed to act on the same brain region. Research builds upon previous research that identified four potential alcohol-sensitive genes in the prefrontal cortex, finding that smoking also influences the expression of these genes.

26 Apr 2006

WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing

A team of scientists from Lawrence Berkeley National Laboratory and the Scripps Research Institute has determined the crystal structure and molecular mechanisms of a key part of WRN, a protein that protects humans from premature aging and cancer.

23 Apr 2006

Primagen awarded U.S. patent for using mitochondrial DNA quantification as biomarker

Primagen Holding BV has announced that the U.S. Patent and Trademark Office has granted a patent for its Mitox mitochondrial DNA quantification technology as biomarkers for efficacy and adverse events of treatment.

19 Apr 2006

miR 155 overexpression can lead to cancer

Scientists in the Ohio State University Comprehensive Cancer Center say that just one, single, malfunctioning microRNA is sufficient to cause cancer in mice.

18 Apr 2006

217 new targets for anti-cancer drugs

By identifying novel genes critical to cancer progression, biologists at the U.S. Department of Energy's Argonne National Laboratory have expanded the number of drug targets researchers have available for study to find ways to stop tumors in their tracks.

18 Apr 2006

Hap1 protein could lead to future drug targets for eating disorders

Researchers have discovered how the protein Hap1, which is abundant in the brain's hypothalamus, serves as the link between circulating insulin in the blood and the neural circuitry that controls feeding behavior in mice.

16 Apr 2006

Researchers determine factors that turn on protein production in bacteria

In the study, published in the journal Molecular Cell, researchers Sean Studer and Simpson Joseph in UCSD's Department of Chemistry and Biochemistry report how the messenger RNA instructions to make a protein are unfolded in a bacterial cell, so that they can be read by the cell's protein-making machinery.

11 Apr 2006

Scientists use corrective gene to block a protein in the kidneys that triggers high blood pressure

Nearly one-third of American adults have high blood pressure, a major cause of heart attacks, strokes and kidney failure. But a new technique tested at the University of Florida could prove to be a long-term way to treat the disorder in humans, researchers say.

11 Apr 2006

Salmonella bacteria use new mechanism known as the riboswitch to adjust magnesium levels

Researchers at Washington University School of Medicine in St. Louis have added a gene in the bacterium Salmonella to the short list of genes regulated by a new mechanism known as the riboswitch.

11 Apr 2006

New approach to treating hepatitis C virus

Last year Peter Sarnow, PhD, professor of microbiology and immunology at the Stanford University School of Medicine, identified a previously unknown mechanism that the hepatitis C virus uses to replicate, yielding a promising new approach to combating the disease-causing virus.

10 Apr 2006

Discovery of new human retrovirus

Howard Hughes Medical Institute researchers and their colleagues have discovered a new retrovirus in humans that is closely related to a cancer-causing virus found in mice. Their findings describe the first documented cases of human infection with a retrovirus that is native to rodents.

10 Apr 2006

Weill Cornell experts publish review of genetic medicine

In an article published in the April issue of Nature Reviews Genetics, two experts at the Weill Medical College of Cornell University sum up the achievements, challenges and promise of a burgeoning field: genetic medicine.

3 Apr 2006

Mouse Brain Gene Expression Map at St. Jude - powerful new tool for studying brain development

Scientists at St. Jude Children's Research Hospital have given investigators around the world free access to a powerful tool for studying brain development.

28 Mar 2006

Study on fruit flies offers new approach to understand human response to viral infections

A research team led by UC Riverside scientists has shown that the common fruit fly can serve as an excellent model for studying the immunity animals are born with for fighting viral infections.

28 Mar 2006

RNAi-based inhibitors for created for nearly every human and mouse gene - available to all genetic researchers

An international public-private research team led by scientists at the Broad Institute of MIT and Harvard announced today the construction and availability of an extensive library of molecular reagents to silence most human and mouse genes.

28 Mar 2006

Successful cell engineering may prevent bovine spongiform encephalopathy (BSE)

Researchers at Texas A&M University have successfully "knocked down" the expression of possible disease-causing genes in a cloned goat fetus, perhaps paving the way for breeding disease resistance in other animals, even those genes that might cause bovine spongiform encephalopathy (BSE), commonly known as Mad Cow Disease.

23 Mar 2006

RNA News and Research

Further Reading

Researchers figure out how nuclear pores duplicate before cells divide

Prefrontal cortex in the brain damaged by both alcoholism and chronic smoking

WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing

Primagen awarded U.S. patent for using mitochondrial DNA quantification as biomarker

miR 155 overexpression can lead to cancer

217 new targets for anti-cancer drugs

Hap1 protein could lead to future drug targets for eating disorders

Researchers determine factors that turn on protein production in bacteria

Scientists use corrective gene to block a protein in the kidneys that triggers high blood pressure

Salmonella bacteria use new mechanism known as the riboswitch to adjust magnesium levels

New approach to treating hepatitis C virus

Discovery of new human retrovirus

Weill Cornell experts publish review of genetic medicine

Mouse Brain Gene Expression Map at St. Jude - powerful new tool for studying brain development

Study on fruit flies offers new approach to understand human response to viral infections

RNAi-based inhibitors for created for nearly every human and mouse gene - available to all genetic researchers

Successful cell engineering may prevent bovine spongiform encephalopathy (BSE)

Scientists identify microRNAs that appear to play a role in the development of platelets

A putative RNA-interference-based immune system in prokaryotes

New understanding of the critical molecular factors that permit viruses to jump from one species to another

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