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Cell phones speed heart attack treatment

A Michigan hospital has cut in half the time it takes to begin life-saving treatment of heart attack patients by using cell phones to transmit electrocardiograms (ECGs) from the field

16 Oct 2005

First gene mutation associated with Tourette syndrome

Researchers have identified the first gene mutation associated with Tourette syndrome - opening a new avenue for understanding the complex disorder that causes muscle and vocal tics.

13 Oct 2005

No shred of evidence that HIV-positive men who lose fat in their legs reciprocally gain fat in their bellies

There is no syndrome that causes increased belly fat and decreased facial and limb fat among HIV-positive men who take antiretroviral drugs, according to a study by researchers at the San Francisco VA Medical Center and the University of California, San Francisco.

13 Oct 2005

Possible links between biting aquatic insects, water quality and Buruli ulcer transmission

A tropical skin disease nicknamed "the sore that heals in vain" wreaks both physical and social mayhem - mostly on children - yet its transmission is a mystery, one an Michigan State University (MSU) researcher and his recent research associate hope to solve.

12 Oct 2005

Obesity associated with a threefold increase in SCD1 expression in obese muscle

The gene encoding an enzyme that hinders muscle from burning fat manufactures three times more enzyme in the muscle of obese people than lean people, researchers from Duke University Medical Center and Louisiana State University have found. This causes the obese muscle tissue to both store more fat and burn less fat, the researchers said.

11 Oct 2005

Sleletal muscle findings highlight the importance of exercise in obese people

The findings suggest that muscle bears a metabolic memory of obesity, which may help to explain why sustained weight loss can be difficult despite cutting calories, according to the researchers. Exercise might more successfully override the aberrant metabolic program in muscle, they suggest, thereby improving the long-term prognosis of those prone to obesity.

11 Oct 2005

Very low LDL cholesterol levels appear to be safe for heart patients on statin therapies

"There was no apparent safety concern for patients whose resultant LDL on intensive therapy was lower than current guidelines. There was a trend toward improved clinical outcomes in the lowest LDL groups," said Stephen D. Wiviott, M.D., from Brigham and Women's Hospital in Boston, Massachusetts.

11 Oct 2005

First study to investigate how heat affects people with heart failure

Reduced blood flow to the skin's surface may be a key cause of heat-related illnesses in patients with congestive heart failure, UT Southwestern Medical Center researchers have found.

10 Oct 2005

Amount of exercise more important than the intensity of the exercise

A study in the October issue of CHEST, the peer-reviewed journal of the American College of Chest Physicians (ACCP), shows that adults who participate in mild exercise, such as walking briskly for 12 miles or exercising for 125 to 200 minutes a week at moderate intensity can significantly improve their aerobic fitness and reduce their risk of cardiovascular disease.

10 Oct 2005

How heat affects people with heart failure

Reduced blood flow to the skin’s surface may be a key cause of heat-related illnesses in patients with congestive heart failure, UT Southwestern Medical Center researchers have found.

10 Oct 2005

Researchers find gene that is important for the control of fundamental rhythms in nematode worms

University of Utah biologists found a gene that controls rhythmic events in a worm's life: swallowing food, laying eggs and pooping.

9 Oct 2005

20 percent of people with chronic hepatitis C who receive a liver transplant will develop advanced cirrhosis

A new study from the University of North Carolina at Chapel Hill School of Medicine may have found a way to identify those at greatest risk, thereby allowing doctors to decide who should receive treatment that could save the transplanted organ. The new findings appear in the October issue of the journal Liver Transplantation.

9 Oct 2005

New data demonstrates how CA4P has anti-tumor and anti-angiogenic activity

Anti-angiogenic agents have been successful in the clinic for blocking the growth of solid tumors. However, these agents used in combination with chemotherapy have improved the survival of patients with cancers by only several months.

9 Oct 2005

Tissue engineering used to reconstruct defective tracheas (windpipes) in fetal lambs

Researchers at Children's Hospital Boston report using tissue engineering to reconstruct defective tracheas (windpipes) in fetal lambs, first using cells from the amniotic fluid to grow sections of cartilage tube, and then implanting these living grafts into the lambs while still in the womb.

9 Oct 2005

GRK5 protein plays important role in hypertension

Researchers at Jefferson Medical College have implicated a protein called GRK5 as having an important role behind essential hypertension, which affects more than 65 million Americans.

5 Oct 2005

PACs should not be used routinely in patients in intensive care units with severe heart failure

The use of a pulmonary artery catheter (PAC) -- a device used for more than 30 years to assess cardiovascular health and to help guide the treatment of critically ill patients -- does not appear to improve outcomes nor confer added risks to patients.

4 Oct 2005

Johns Hopkins awarded $12 million to study how stem cell therapies can be used to treat hearts damaged by heart attack

Heart specialists at Johns Hopkins Heart Institute have been awarded more than $12 million from the National Heart, Lung, and Blood Institute (NHLBI) to study how stem cell therapies can be used to treat hearts damaged by heart attack or heart failure.

4 Oct 2005

Potential biomarker that could be used to predict who might develop hepatic fibrosis

Two new studies on Hepatitis C (HCV) patients who underwent liver transplants examined a potential biomarker that could be used to predict who might develop hepatic fibrosis, a formation of scar-like tissue that can lead to cirrhosis.

3 Oct 2005

New insights that advance the current model of protein motility and muscle contraction

Scientists from the Burnham Institute for Medical Research and the University of Vermont have captured the first 3-dimensional (3D) atomic-resolution images of the motor protein myosin V as it "walks" along other proteins, revealing new structural insights that advance the current model of protein motility and muscle contraction.

3 Oct 2005

HeartMate XVE left ventricular assist device

Nine years ago this week, a team of University of Michigan doctors gave a dying heart patient a second chance at life by implanting a high-tech pump in his chest. The high-risk procedure was the first in Michigan performed using a new blood-pumping device called a HeartMate XVE left ventricular assist device, which helped the patient live until he received a heart transplant five weeks later.

28 Sep 2005

Muscle News and Research

Cell phones speed heart attack treatment

First gene mutation associated with Tourette syndrome

No shred of evidence that HIV-positive men who lose fat in their legs reciprocally gain fat in their bellies

Possible links between biting aquatic insects, water quality and Buruli ulcer transmission

Obesity associated with a threefold increase in SCD1 expression in obese muscle

Sleletal muscle findings highlight the importance of exercise in obese people

Very low LDL cholesterol levels appear to be safe for heart patients on statin therapies

First study to investigate how heat affects people with heart failure

Amount of exercise more important than the intensity of the exercise

How heat affects people with heart failure

Researchers find gene that is important for the control of fundamental rhythms in nematode worms

20 percent of people with chronic hepatitis C who receive a liver transplant will develop advanced cirrhosis

New data demonstrates how CA4P has anti-tumor and anti-angiogenic activity

Tissue engineering used to reconstruct defective tracheas (windpipes) in fetal lambs

GRK5 protein plays important role in hypertension

PACs should not be used routinely in patients in intensive care units with severe heart failure

Johns Hopkins awarded $12 million to study how stem cell therapies can be used to treat hearts damaged by heart attack

Potential biomarker that could be used to predict who might develop hepatic fibrosis

New insights that advance the current model of protein motility and muscle contraction

HeartMate XVE left ventricular assist device

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