Hippocampus News and Research

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The hippocampus is a part of the forebrain, located in the medial temporal lobe. It belongs to the limbic system and plays major roles in short term memory and spatial navigation. Humans and other mammals have two hippocampi, one in each side of the brain.

Study reveals how ketogenic diet protects against epilepsy seizures

University of Virginia School of Medicine researchers have revealed how the popular, low-carb ketogenic diet protects against epilepsy seizures and possibly neurodegenerative diseases such as Alzheimer's and Parkinson's.

16 Jan 2026

Alternative splicing of DOC2A gene shown to drive schizophrenia risk

In an important new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of the DOC2A gene in schizophrenia.

16 Jan 2026

Deep brain region could be crucial for preserving physical strength during aging

A new study suggests that a little-known region deep in the brain could be crucial for preserving physical strength as we age. The findings could help detect and prevent frailty before it begins.

13 Jan 2026

Study sheds new light on how structural brain changes are tied to memory decline in aging

A landmark international study that pooled brain scans and memory tests from thousands of adults has shed new light on how structural brain changes are tied to memory decline as people age.

13 Jan 2026

Single-cell analysis reveals gene disruptions in early-onset Alzheimer's brain regions

A new study led by researchers at UTHealth Houston investigated both gene expression and regulation at single cell levels to reveal disruptions in gene function in three brain regions of patients with sporadic early onset Alzheimer's disease.

13 Jan 2026

Sex-based differences and role of BMP signaling in neurogenesis in Alzheimer's mice models

Alzheimer's disease (AD) is a serious neurodegenerative disease largely affecting older adults. Apart from age, it also shows sex-based differences, with women being more at risk. However, the origin of these differences remains unknown.

9 Jan 2026

Scientists discover how stem cells navigate and repair brain damage after stroke

Some parts of our bodies bounce back from injury in fairly short order. The outer protective layer of the eye-called the cornea-can heal from minor scratches within a single day.

8 Jan 2026

Separate neurons for content and context enable flexible human memory

The human brain must be able to link memory content to the circumstances in which it occurs. Researchers in Bonn have now discovered how the human brain uses two different groups of neurons to store content and context separately.

7 Jan 2026

Simple drug treatments could help older brains cope with memory decline and postoperative recovery

Simple pharmaceutical interventions could help older brains cope with memory impairment and recovery after surgery, new studies in mice suggest.

6 Jan 2026

Understanding sevoflurane-induced neurogenesis inhibition and cognitive dysfunction in children

Every year, millions of infants and children undergo surgery under general anesthesia in the world. Sevoflurane is a commonly used pediatric anesthetic. Its exposure during brain development has been shown to inhibit neurogenesis and cause cognitive dysfunction in animal models.

5 Jan 2026

Targeting CSE enzyme may offer new pathways for Alzheimer’s treatment

Scientists at Johns Hopkins Medicine say results of a new National Institutes of Health-funded study are advancing efforts to exploit a new target for Alzheimer's disease: a protein that manufactures an important gas in the brain.

30 Dec 2025

Experimental drug targets early toxic amyloid to slow Alzheimer’s disease

An experimental drug developed at Northwestern University has demonstrated further promise as an early intervention for Alzheimer's disease.

18 Dec 2025

How the brain tracks distance in the dark without landmarks

Whether you are heading to bed or seeking a midnight snack, you don't need to turn on the lights to know where you are as you walk through your house at night.

17 Dec 2025

Scientists reveal how the brain reshapes episodic memories over time

A study from the University of East Anglia is helping scientists better understand how our brains remember past events - and how those memories can change over time.

4 Dec 2025

Hidden cellular layers in the hippocampus' CA1 region revealed

Researchers at the Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC have identified a previously unknown pattern of organization in one of the brain's most important areas for learning and memory.

3 Dec 2025

Chronic drinking weakens the blood-brain barrier through the gut

Chronic alcohol consumption disrupts the blood-brain barrier, but Faecalibacterium prausnitzii shows promise in repairing this damage and improving cognition.

27 Nov 2025

Researchers use "zap-and-freeze" technique to watch hard-to-see brain cell communications

Researchers at Johns Hopkins Medicine say they have used a "zap-and-freeze" technology to watch hard-to-see brain cell communications in living brain tissue from mice and humans.

25 Nov 2025

Deficient ATP release in the brain drives depressive- and anxiety-like behaviors

In a new JNeurosci paper, Tian-Ming Gao and colleagues, from Southern Medical University, explored how adenosine triphosphate (ATP) signaling relates to depression and anxiety using male mice. ATP is a molecule that not only provides energy but also supports communication between neurons.

25 Nov 2025

Arginine slows amyloid buildup and improves brain outcomes in Alzheimer’s disease models

Arginine reduced amyloid beta aggregation in vitro and in both Drosophila and AppNL-G-F mouse models of Alzheimer’s disease, leading to fewer dense-core plaques and improved behavior. The study provides preclinical evidence that oral arginine may modulate amyloid pathology, although high dosing requirements and model limitations constrain human translation.

24 Nov 2025

Study finds GLP-1 drugs improve strength and reverse aging biology in mice

Researchers showed that GLP-1 receptor agonism counteracts aging across multiple organs in mice, improving strength and reversing molecular aging signatures without meaningful effects on body weight. These benefits depended largely on hypothalamic GLP-1R signaling and closely mirrored the anti-aging patterns produced by rapamycin.

23 Nov 2025

Hippocampus News and Research

Further Reading

Study reveals how ketogenic diet protects against epilepsy seizures

Alternative splicing of DOC2A gene shown to drive schizophrenia risk

Deep brain region could be crucial for preserving physical strength during aging

Study sheds new light on how structural brain changes are tied to memory decline in aging

Single-cell analysis reveals gene disruptions in early-onset Alzheimer's brain regions

Sex-based differences and role of BMP signaling in neurogenesis in Alzheimer's mice models

Scientists discover how stem cells navigate and repair brain damage after stroke

Separate neurons for content and context enable flexible human memory

Simple drug treatments could help older brains cope with memory decline and postoperative recovery

Understanding sevoflurane-induced neurogenesis inhibition and cognitive dysfunction in children

Targeting CSE enzyme may offer new pathways for Alzheimer’s treatment

Experimental drug targets early toxic amyloid to slow Alzheimer’s disease

How the brain tracks distance in the dark without landmarks

Scientists reveal how the brain reshapes episodic memories over time

Hidden cellular layers in the hippocampus' CA1 region revealed

Chronic drinking weakens the blood-brain barrier through the gut

Researchers use "zap-and-freeze" technique to watch hard-to-see brain cell communications

Deficient ATP release in the brain drives depressive- and anxiety-like behaviors

Arginine slows amyloid buildup and improves brain outcomes in Alzheimer’s disease models

Study finds GLP-1 drugs improve strength and reverse aging biology in mice

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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