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Investigational anti-interleukin-6 monoclonal antibody achieves durable inflammatory biomarker reductions

The investigational anti-interleukin-6 (IL-6) monoclonal antibody pacibekitug produced sustained reductions in inflammation-related biomarkers through six months in patients with chronic kidney disease and elevated inflammatory risk associated with heart disease.

29 Aug 2026

Pacibekitug safely reduces inflammatory biomarkers in kidney disease patients

The interleukin-6 (IL-6) antibody, pacibekitug, produced sustained reductions in inflammatory biomarkers in patients with chronic kidney disease at high inflammatory risk, according to results from the phase II TRANQUILITY trial presented in a Hot Line session today at ESC Congress 2026.

29 Aug 2026

Researchers identify early molecular warning signs of inflammatory bowel disease

Researchers have uncovered early molecular warning signs of inflammatory bowel disease, revealing the condition can begin before symptoms appear and continue silently even when patients appear well.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 29 Aug 2026

FDA approves daraxonrasib for metastatic pancreatic cancer following landmark clinical trial led by Dana-Farber

The U.S. Food and Drug Administration (FDA) has approved daraxonrasib, an oral multi-selective RAS(ON) inhibitor, for adults with metastatic pancreatic adenocarcinoma who have received at least one prior systemic therapy or are not candidates for multiagent systemic therapy.

From Dana-Farber Cancer Institute, Inc. 29 Aug 2026

New stroke guidelines could help pave the way for precision rehabilitation

A University of Maryland School of Medicine (UMSOM) stroke rehabilitation specialist helped develop new recommendations for studying molecular biomarkers associated with recovery from stroke.

28 Aug 2026

Specialized blood vessel cells found to actively drive lung fibrosis

Millions of people worldwide are affected by diseases that cause scarring of the lungs, often leading to breathing difficulties and reduced quality of life.

28 Aug 2026

Cell proliferation gene plays a distinct role in cells that no longer proliferate

In a tale of identities as divergent as "The Prince and the Pauper," a well-known cancer-causing gene also influences cells in a zombie-like state meant to prevent cancer.

28 Aug 2026

Study identifies role for peroxisomes in protecting insulin and maintaining beta cell health

Researchers at LSU's Pennington Biomedical Research Center have identified a previously underappreciated role for tiny structures inside cells called peroxisomes in protecting insulin and maintaining the health and maturity of insulin-producing pancreatic beta cells.

28 Aug 2026

Probiotics for mental health? A new review finds promising signals and major gaps

This narrative review examines how psychobiotics may influence anxiety, depression, bipolar disorder, and schizophrenia through gut-brain pathways involving neurotransmitters, inflammation, immune regulation, gut barrier function, and stress signaling. Specific Lactobacillus and Bifidobacterium strains showed encouraging effects, but wide differences in strains, doses, populations, and study designs currently limit clinical translation.

28 Aug 2026

Scientists reviewed 20 edible and medicinal fungi for clues to better prebiotics

A review of 20 non-toxic edible and medicinal fungal species found that their polysaccharides can resist digestion, interact with gut microbes, and influence microbial metabolites linked to intestinal and metabolic health. The evidence suggests potential benefits for conditions including colitis, type 2 diabetes, and obesity, although most findings currently come from laboratory and animal studies.

27 Aug 2026

CAR T-cell therapy successfully reverses severe rheumatoid arthritis

Immunotherapies such as CAR T-cell therapy are used primarily to treat cancer. In the future, these patient-specific therapies, manufactured from patients' own immune cells, could also help cure autoimmune diseases.

27 Aug 2026

New mutant rat model replicates human chronic kidney disease

Chronic kidney disease (CKD) is a major health burden affecting approximately one in ten adults globally. Even with improved treatments, many patients continue to have worsening loss of kidney function, resulting in the need for dialysis or transplantation.

27 Aug 2026

Cellular glue protein found to help clear away dead cells

A protein which sticks cells and tissues together has been found to have a surprising second job: helping cells which are packed into a continuous sealed layer, also known as epithelial cells, engulf nearby dead cells.

27 Aug 2026

Overuse of short-acting bronchodilator linked to increased risk of cardiovascular diseases and death

Overuse of reliever inhalers is associated with higher risks of developing and dying from cardiovascular disease, including heart failure, heart attack and ischemic stroke, in asthma and COPD patients, according to a study published today in ERJ Open Research.

27 Aug 2026

Gut microbiome atlas maps how bacteria establish themselves and shift in inflammatory bowel disease

Researchers created a microbiome-wide atlas mapping more than seven million colonization factor genes across 4,716 human gut microbial species, revealing three putative strategies linked to metabolism, stress resistance, and microbial communication. Applying the framework to inflammatory bowel disease showed that colonization-factor profiles can provide a compact, biologically interpretable view of disease-associated microbiome changes.

27 Aug 2026

FDA approves first RAS-targeted therapy for metastatic pancreatic cancer

27 Aug 2026

Maternal immune response to urinary tract infection may drive preterm birth risk

A new study published in Science Translational Medicine shows that the increased risk of preterm pregnancies associated with urinary tract infection (UTI), is linked to the body's immune response to the infection rather than to the bacteria themselves.

26 Aug 2026

Phytoene in tomatoes may help protect against fatty liver disease

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Inflammation News and Research

Investigational anti-interleukin-6 monoclonal antibody achieves durable inflammatory biomarker reductions

Pacibekitug safely reduces inflammatory biomarkers in kidney disease patients

Researchers identify early molecular warning signs of inflammatory bowel disease

FDA approves daraxonrasib for metastatic pancreatic cancer following landmark clinical trial led by Dana-Farber

New stroke guidelines could help pave the way for precision rehabilitation

Specialized blood vessel cells found to actively drive lung fibrosis

Cell proliferation gene plays a distinct role in cells that no longer proliferate

Study identifies role for peroxisomes in protecting insulin and maintaining beta cell health

Probiotics for mental health? A new review finds promising signals and major gaps

Scientists reviewed 20 edible and medicinal fungi for clues to better prebiotics

CAR T-cell therapy successfully reverses severe rheumatoid arthritis

New mutant rat model replicates human chronic kidney disease

Cellular glue protein found to help clear away dead cells

Overuse of short-acting bronchodilator linked to increased risk of cardiovascular diseases and death

Gut microbiome atlas maps how bacteria establish themselves and shift in inflammatory bowel disease

FDA approves first RAS-targeted therapy for metastatic pancreatic cancer

Maternal immune response to urinary tract infection may drive preterm birth risk

Phytoene in tomatoes may help protect against fatty liver disease

Research improves understanding of biological mechanisms behind cluster headaches

Study links finasteride to fewer complications after heart attack in men

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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