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A single drug stabilizes nearly all mutations of key kidney protein

A study published today in Nature Structural & Molecular Biology is the first time researchers have shown evidence that a single drug, already licensed for medical use, can stabilize nearly all mutated versions of a human protein, regardless of where the mutation is in the sequence.

23 Sep 2025

Scientists use blood chemistry to predict disease years before it strikes

Researchers built the largest plasma metabolome-phenome atlas using 274,241 UK Biobank participants, linking over 73,000 metabolite-trait and 52,000 metabolite-disease associations. The study shows metabolic risk scores can predict diseases years before diagnosis, with strong accuracy for diabetes and kidney complications.

22 Sep 2025

Two-step blood and scan strategy delivers near-perfect accuracy for early Alzheimer's signs

Plasma p-tau217 testing can help detect preclinical Alzheimer disease in cognitively unimpaired adults. Using it as a first-line screen followed by positron emission tomography or cerebrospinal fluid testing boosts accuracy, reduces false positives, and streamlines recruitment.

16 Sep 2025

Inside the lab of the future: Automation, NMR, and the power of integration

Discover how Bruker is changing the future of labs and NMR through its R&D efforts.

From Bruker BioSpin Group 16 Sep 2025

Streamlining CAR T cell production through in vivo therapeutic strategies

This review article highlights the transformative potential of in vivo CAR T cell therapy in addressing the limitations of traditional CAR T cell production.

5 Sep 2025

How raspberry leaf tea reduces insulin surges from table sugar

Trial shows that raspberry leaf tea blunts sucrose-induced glucose and insulin surges, offering a natural strategy for moderating blood sugar without the side effects of pharmaceutical enzyme inhibitors.

2 Sep 2025

Disrupting protein quality control slows tumor growth in pediatric rhabdomyosarcoma

A new research paper was published in Volume 16 of Oncotarget on August 29, 2025, titled "In vivo manipulation of the protein homeostasis network in rhabdomyosarcoma."

29 Aug 2025

Mediterranean diet lowers dementia risk by altering key metabolites

Researchers linked genetics, plasma metabolites, and Mediterranean diet adherence to dementia risk in two large US cohorts, showing APOE4 homozygotes had distinct metabolic pathways. Diet-related metabolites mediated protection, highlighting precision-prevention opportunities.

26 Aug 2025

Synthetic Psychedelics: A Growing Public Health Concern

In this interview, Jonathan Ferguson discusses how knowledge of an emerging public health concern identified at Pittcon 2024 has evolved a year on.

From Pittcon 26 Aug 2025

Fat location, not BMI, drives heart ageing risk in men and women

Researchers using UK Biobank imaging data found that where fat is stored in the body, not just how much, determines cardiovascular ageing. Visceral, liver, and muscle fat accelerate ageing, while gynoid fat protects women before menopause.

25 Aug 2025

How leadership drives inspection readiness from the top down

Discover how proactive leadership sets the tone for inspection readiness across all levels of an organization.

From DSI, a PLG Company 25 Aug 2025

Natural products offer promising solutions in prosthodontics and oral implantology

Infection control is paramount in prosthodontics and oral implantology to prevent complications like denture stomatitis and peri-implantitis.

22 Aug 2025

Investigation raises concerns over tooth stem cell banking claims

Parents are spending thousands of pounds to bank stem cells from their children's milk teeth – but the recipient companies' claims about their future medical value are unproven and potentially misleading, reveals an investigation by The BMJ, published today.

21 Aug 2025

Hybrid reading strategy for screening mammography reduces radiologist workload

A hybrid reading strategy for screening mammography, developed by Dutch researchers and deployed retrospectively to more than 40,000 exams, reduced radiologist workload by 38% without changing recall or cancer detection rates.

19 Aug 2025

FastUKB transforms UK Biobank research with seamless data extraction and analysis

FastUKB is an innovative tool specifically developed to streamline and enhance research workflows utilizing the UK Biobank, effectively addressing key limitations of existing platforms such as the UK Biobank Research Analysis Platform (RAP).

18 Aug 2025

RNA quality control protein PELOTA found to slow aging and extend lifespan

As aging progresses, the quality of DNA and proteins inside cells declines, known to be the cause of various degenerative diseases.

18 Aug 2025

Alzheimer’s gene risks differ by ancestry, major study reveals 133 new variants

Researchers used whole-genome sequencing from diverse populations to identify 156 variants, including 133 novel ones, linked to Alzheimer’s disease and related dementias. The study highlights ancestry-specific genetic risk and protective factors, challenging one-size-fits-all approaches to dementia genetics.

17 Aug 2025

DIVA celebrates 30th anniversary with three milestone product launches and new website debut

DIVA, a professional medical display manufacturer with 30 years of experience, announces three major product developments that reinforce its commitment to high-performance imaging solutions.

From DIVA Labs 13 Aug 2025

EVIDENT to Acquire Pramana, Inc.

Evident announces a definitive agreement to acquire Pramana, Inc., a leading manufacturer of digital pathology solutions.

13 Aug 2025

Microplastics found in all popular UK drinks, with hot beverages worst offenders

Researchers found microplastics in every hot and cold beverage tested in the UK, with higher levels in hot drinks and packaging as the main source. Beverage consumption was shown to significantly increase daily microplastic intake beyond water-only estimates.

11 Aug 2025