Super resolution microscopy News and Research

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Super-resolution tools have made it possible to break the diffraction barrier and resolve objects as small as 10-20 nm.

Worldwide Protein Data Bank symposium focuses on multi-scale structural biology

The symposium titled with "Integrative Structural Biology with Hybrid Methods" is held focusing on the multi-scale structural biology, which aims to analyze structures of protein molecules and their assemblies, cellular machines, organelle, and even living cells and organisms by the hybrid methods, integrating many different technologies, such as chemical cross-links, MS spectrometry, FRET, Super-resolution microscopy, X-ray diffraction, NMR, and Computer modeling, in addition to Cryo-electron microscopy that has been attracting much attention these days.

10 Sep 2015

Trio of Andor EMCCD cameras chosen to unravel the inner structure of Herpes simplex virus

Although super-resolution light microscopy has broken new ground in our understanding of subcellular structures and the movement of individual molecules within cells, its use to investigate virus particles is in its infancy...

From Andor Technology Ltd. 14 Apr 2015

Super-resolution microscopes reveal the link between genome packaging and cell pluripotency

In 1953 Watson and Crick first published the discovery of the double helix structure of the DNA. They were able to visualize the DNA structure by means of X-Ray diffraction. Techniques, such as electron microscopy, allowed scientists to identify nucleosomes, the first and most basic level of chromosome organisation

13 Mar 2015

Accessible TIRF solutions for every application

Olympus expands its range of cellTIRF illuminators and accessories with the new economic one-line illuminator (cellTIRF-1L), which complements the high-end, 4- and 2-line (cellTIRF MITICO 4L/2L) illuminators.

From Evident Corporation - Life Sciences 10 Feb 2015

Smart route to confocal Super Resolution microscopy introduced by Olympus

Thanks to a novel software upgrade from Olympus, an optical resolution of up to 120 nm is now achieved in cell and tissue imaging. With the new Olympus FV-OSR software, the FluoView FV1200 is transformed into a powerful system for confocal Super Resolution microscopy.

From Evident Corporation - Life Sciences 3 Oct 2014

Live cell imaging solution launched by QImaging

QImaging™ today launched a new, all-in-one camera package that supports demanding live cell fluorescence imaging requirements. The Live Cell Imaging Package provides researchers with the sensitivity of EMCCD and the versatility of sCMOS camera technologies by combining QImaging’s Rolera™ Thunder EMCCD and optiMOS™ sCMOScameras. Now, researchers can address their unique imaging needs for a broader, more diverse set of scientific applications.

21 Aug 2014

New fluorescent molecule paves way for easier and higher quality imaging of cells

Like our own bodies, cells have their own skeletons called 'cytoskeletons' and are made of proteins instead of bones.

26 May 2014

Self-assembling DNA cages hold potential promise in drug delivery

Move over, nanotechnologists, and make room for the biggest of the small. Scientists at the Harvard's Wyss Institute have built a set of self-assembling DNA cages one-tenth as wide as a bacterium.

17 Mar 2014

GE announces winners of the GE Healthcare 2013 Cell Imaging Competition

GE Healthcare Life Sciences (NYSE:GE) today announced Vanessa Auld from Canada, Martin Barr from Ireland and Graham Wright from Singapore as the winners of the GE Healthcare 2013 Cell Imaging Competition.

12 Mar 2014

New super-resolution microscopy method could spot dozens of distinct types of biomolecules

A new microscopy method could enable scientists to generate snapshots of dozens of different biomolecules at once in a single human cell, a team from the Wyss Institute of Biologically Inspired Engineering at Harvard University reported Sunday in Nature Methods.

4 Feb 2014

Study quantifies photoactivation efficiency of fluorescent proteins

To know how many proteins assemble together at the nanoscale is fundamental for understanding protein function. Sometimes, proteins must be in an "oligomeric" state to be functional, although "oligomerization" of certain proteins can also lead to diseases. The ability to determine protein stoichiometry and monitor changes in the balance between monomeric, dimeric and multi-meric proteins can allow scientists to see the differences between a properly functioning cell and a diseased cell. Therefore, there is a great interest in being able to count proteins and determine their stoichiometry.

7 Jan 2014

Harvard University receives $3.5M grant to develop super-resolution microscopy technique

A team at the Wyss Institute for Biologically Inspired Engineering at Harvard University has been awarded a special $3.5 million grant from the National Institutes of Health (NIH) to develop an inexpensive and easy-to-use new microscopy method to simultaneously spot many tiny components of cells.

4 Oct 2013

Indiana researcher uses OMX light microscope to image mitosis process

Like a pair of dancers sheathed in blue, two chromosomes take the cell's center stage in this scene from the elegant—and usually perfectly performed—process of mitosis.

22 Apr 2013

Super-resolution microscopy highlights bacterial biofilms

A multi-fluorescent labeling strategy combined with super-resolution light microscopy has allowed researchers to observe the development of a bacterial biofilm in realtime.

18 Jul 2012

DRCRF names 21 new Damon Runyon Fellows

The Damon Runyon Cancer Research Foundation, a non-profit organization focused on supporting innovative early career researchers, named 21 new Damon Runyon Fellows at its spring Fellowship Award Committee review.

11 Jul 2012

Super-resolution microscopy technique reveals how and why cell's defenses fail against plague

Researchers at Sandia National Laboratories have developed a super-resolution microscopy technique that is answering long-held questions about exactly how and why a cell's defenses fail against some invaders, such as plague, while successfully fending off others like E.coli.

17 May 2011

GE Healthcare reaches agreement to acquire Applied Precision

GE Healthcare, a unit of General Electric Company, today announced it has reached an agreement to acquire Applied Precision, Inc., a supplier of innovative cellular imaging technologies for the fast-growing cell biology and biomedical research sectors.

28 Apr 2011

Bessel beam plane illumination microscopy reveals 3-D structures of living cells

A new microscope invented by scientists at Howard Hughes Medical Institute's Janelia Farm Research Campus will let researchers use an exquisitely thin sheet of light -- similar to that used in supermarket bar-code scanners -- to peer inside single living cells, revealing the three-dimensional shapes of cellular landmarks in unprecedented detail.

5 Mar 2011

Malaria parasite caught in action on film for the first time

Australian researchers have managed to take pictures of microscopic malaria parasite as it invades a human red blood cell. This will provide a deeper understanding of the parasite’s behaviour and may help fight it. Up to 10% of the world’s population contract malaria every year and a million people, mostly pregnant women and children, die as a result of the parasite transmitted by infected mosquitoes.

19 Jan 2011

Applied Precision installs 4 DeltaVision OMX super- resolution imaging systems in 8 weeks

Applied Precision, a leader in life science imaging solutions, is proud to announce the installation of four of its revolutionary DeltaVision OMX® super- resolution imaging system in a record timeframe of eight weeks.

12 Nov 2010