Worldwide Protein Data Bank symposium focuses on multi-scale structural biology

The symposium titled with "Integrative Structural Biology with Hybrid Methods" is held focusing on the multi-scale structural biology, which aims to analyze structures of protein molecules and their assemblies, cellular machines, organelle, and even living cells and organisms by the hybrid methods, integrating many different technologies, such as chemical cross-links, MS spectrometry, FRET, Super-resolution microscopy, X-ray diffraction, NMR, and Computer modeling, in addition to Cryo-electron microscopy that has been attracting much attention these days.

By the invited speakers to the symposium, their researches with the hybrid methods are introduced, and construction of a new database with data validation and putative applications to drug discovery will be discussed.

This Symposium is held as an outreach of The wwPDB Foundation (The worldwide Protein Data Bank Foundation) for its educational and social contributions.

The participation fees or prior registrations are not necessary. Your participation is highly welcome.


8:30 Open of the Auditorium
9:00 Opening Remarks Haruki Nakamura (PDBj, Osaka Univ)

Session 1: Integrative Structural Biology as a New Trend of Life Science
Chair John L. Markley (BMRB, Univ Wisconsin)
9:10 Helen M. Berman (wwPDB, Rutgers Univ)
9:40 Andrej Sali (UCSF)
10:10 Wah Chiu (Baylor College of Medicine)

10:40 - 11:00 Coffee Break

Session 2: Power of Current Cryo-Electron Microscopy Chair Manju Bansal (Indian Inst of Science)
11:00 Takashi Fujii (Osaka Univ)
11:30 Helen Saibil (Birkbeck College)
12:00 Kenji Iwasaki (Osaka Univ)

12:30 - 14:00 Lunch

Session 3: Applications of Hybrid Methods Chair Cynthia Wolberger (Johns Hopkins Univ)
14:00 Angela Gronenborn (Univ Pittsburgh)
14:30 Florence Tama (RIKEN)
15:00 Takeshi Kawabata (Osaka Univ)

15:30 - 15:50 Coffee Break

Session 4: Applications and Validations of Hybrid Methods Chair Edward Baker (Univ Auckland)
15:50 Mitsunori Ikeguchi (Yokohama City Univ)
16:20 Paul Adams (Lawrence Berkeley Laboratory)
16:50 Gerard Kleywegt (PDBe, EBI)
17:20 R. Andrew Byrd (NCI at Frederick)

17:50 Closing Remarks Stephen K Burley (RCSB-PDB, Rutgers Univ)


Osaka University


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