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Study establishes link between Piezo1 and intracellular cholesterol levels during neural development

A new University of California, Irvine-led study reveals how mechanical forces and tissue mechanics influence the morphology of the developing brain, and establishes a direct link in neural stem cells between Piezo1, a mechanically-activated ion channel, and intracellular cholesterol levels during neural development.

8 Sep 2022

Administering immunotherapy drug before surgery for oral cavity cancer did not increase complications

A University of Cincinnati study found administering an immunotherapy drug before surgery for oral cavity cancer did not lead to increased rates of complications during and after surgery.

7 Sep 2022

Research shows how orderly regeneration is activated after injury

The phenomenon of regeneration was discovered over 200 years ago in the freshwater polyp Hydra. Until now, however, it was largely unclear how the orderly regeneration of lost tissues or organs is activated after injury.

2 Sep 2022

3 shots in 1: How microparticles could be used to deliver self-boosting vaccines

In this interview, we speak to Morteza Sarmadi from MIT about his labs latest research that developed microparticles able to deliver self-boosting vaccines.

30 Aug 2022

High-throughput proteomics reveals pregnancy-specific responses to COVID-19

Researchers evaluated pregnancy-specific responses to SARS-CoV-2 infection.

29 Aug 2022

Researchers discover the vital role of immune cells in liver regeneration

If liver tissue has to be removed due to cancer or another liver disease, the organ usually regenerates quickly, soon becoming fully functional once again.

24 Aug 2022

Cornea implant made of collagen from pig’s skin restores vision

In this interview, News-Medical speaks to Professors Neil Lagali and Mehrdad Rafat about their latest research, which detailed a bioengineered corneal tissue for minimally invasive vision restoration in advanced keratoconus in two clinical cohorts.

23 Aug 2022

Study shows how the same protein that is key for brain development can also be the cause for the spread of cancer

Researchers at Queen's University Belfast have revealed how the pathway of an identified protein could lead to early diagnosis and targeted treatment for several cancers and brain disorders.

10 Aug 2022

Aberrant levels of three microRNAs may impair healing in venous ulcers, study shows

The study, which includes the first resource detailing the role of microRNAs in the wound-repair process, shows that aberrant levels of a trio of microRNAs may impair healing in venous ulcers.

9 Aug 2022

Vitamin A supplementation is missed by two in five children in India, analysis finds

Two in five eligible children in India are missing out on preventive vitamin A supplementation designed to ward off the health problems associated with deficiency of the vitamin, finds an analysis of representative survey data, published in the open access journal BMJ Global Health.

29 Jul 2022

New technology converts discarded bullfrog skin into wound healing products

A new clinical-grade collagen made from discarded bullfrog skin is leapfrogging from the lab bench to clinics soon.

27 Jul 2022

Tissue nanotransfection technology can serve as a non-viral, topical, gene-editing delivery device, research shows

The Indiana Center for Regenerative Medicine and Engineering (ICRME) at Indiana University School of Medicine is home to tissue nanotransfection (TNT) regenerative medicine technology that achieves functional tissue reprogramming in the live body.

19 Jul 2022

Chemokine-DNA nanoparticles can induce chronic, dysfunctional immune responses

Small proteins, called chemokines, that direct immune cells toward sites of infection can also form DNA-bound nanoparticles that can induce chronic, dysfunctional immune responses, according to a new study by researchers at Weill Cornell Medicine and Hospital for Special Surgery (HSS).

15 Jul 2022

The role of myostatin in female fertility

A new study discusses some of the key functions of myostatin in female reproductive health and disease.

6 Jul 2022

How does obesity affect the immune system?

A new study summarizes new findings on the immunoregulatory effects of excessive fat stores or malnutrition through Th2 cells.

4 Jul 2022

Researchers develop new method based on magneto-active polymers to study cellular behavior

Scientists from 4D-BIOMAP, an ERC research project at the Universidad Carlos III de Madrid (UC3M), have developed a new experimental method, based on magneto-active polymers, to study cellular behavior.

28 Jun 2022

Researchers highlight the impact of macrophage subtypes on acute kidney injury to CKD transition

Acute kidney injury (AKI) is a condition in which kidneys are unable to filter waste from the blood effectively, leading to various health complications.

20 Jun 2022

AKT inhibitor miransertib could be a promising new treatment against low-flow vascular malformations

A team of researchers led by Dr. Sandra Castillo and Dr. Mariona Graupera, from the Josep Carreras Leukaemia Research Institute and member of the CIBERONC, have found the AKT inhibitor miransertib could be a new molecular treatment effective against low-flow vascular malformations, a long-awaited milestone.

14 Jun 2022

Electro-chemical bandages could be an effective alternative to antibiotics for managing wound infections

According to new research by investigators at the Mayo Clinic and Washington State University, e-bandages could be an effective alternative to antibiotics for managing wound infections. The findings are presented at ASM Microbe 2022, the annual meeting of the American Society for Microbiology.

13 Jun 2022

Biodegradable piezoelectric film could help regenerate the native cartilage after knee damage

Osteoarthritis – a painful condition that results from the deterioration of the cartilage in our joints – affects millions of people worldwide.

3 Jun 2022