Macrophage News and Research

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A macrophage is a type of white blood cell that surrounds and kills microorganisms, removes dead cells, and stimulates the action of other immune system cells.

Researchers create vaccine that protects against malaria in mouse models

A Yale-led team of researchers have created a vaccine that protects against malaria infection in mouse models, paving the way for the development of a human vaccine that works by targeting the specific protein that parasites use to evade the immune system.

13 Jul 2018

Study demonstrates new therapeutic targets for inflammation-associated colon cancer

Scientists headed by ICREA researcher Angel R. Nebreda at the Institute for Research in Biomedicine (IRB Barcelona) report a new mechanism that contributes to the development of inflammation-associated colon cancer and points to new therapeutic targets. The study has been published in the journal EMBO Molecular Medicine.

12 Jul 2018

New clinical trial to evaluate virotherapy and immunotherapy combination for ovarian, colorectal cancers

Ludwig Cancer Research and the Cancer Research Institute announce the initiation of a clinical trial to evaluate the combination of ONCOS-102, an experimental anti-tumor virotherapy, with the checkpoint blockade antibody IMFINZI (durvalumab) for advanced ovarian and colorectal cancers.

12 Jul 2018

Scientists pinpoint new therapeutic targets for inflammation-associated colon cancer

Scientists headed by ICREA researcher Angel R. Nebreda at the Institute for Research in Biomedicine report a new mechanism that contributes to the development of inflammation-associated colon cancer and points to new therapeutic targets

11 Jul 2018

Study reveals how M. tuberculosis escapes death in macrophages

The bacteria that cause the devastating disease tuberculosis have the ability to escape destruction and grow after they are engulfed by lung macrophages, the immune cells that are supposed to destroy pathogens.

10 Jul 2018

New TSPO-targeted PET imaging more fully evaluates extent of rheumatoid arthritis

A new positron emission tomography imaging method more fully evaluates the extent of rheumatoid arthritis by targeting translocator protein expression in the synovium (joint lining tissue).

10 Jul 2018

Scientists discover new target to treat blood vessel damage in diabetes

In diabetes, both the tightly woven endothelial cells that line our blood vessels and the powerhouses that drive those cells start to come apart as early steps in the destruction of our vasculature.

9 Jul 2018

Non-opioid drug shows promise for treating pain by targeting receptors on immune cells

Faced with the epidemic of opioid addiction, researchers have been charged with finding other strategies to treat pain. Their efforts largely have focused on nerve cells that transmit pain signals to the spinal cord and brain.

6 Jul 2018

Scientists take a deep dive into differences between Zika and dengue virus

More than two years after reports of skyrocketing Zika rates surfaced worldwide, questions still loom about this complicated virus.

6 Jul 2018

Scientists use stem cells to uncover why the Zika virus is so infective

Researchers have made an important discovery about the Zika virus that could lead to the development of more effective measures to protect people.

5 Jul 2018

Seeing the Unexpected: Regulatory T Cells and Basophils

Dr. Jagadeesh Bayry from INSERM discusses his recent research in the field of immunology, and how T regulatory cells activate, rather than suppress, basophils.

4 Jul 2018

Scientists discover way to increase efficiency of mature blood production in a dish

Scientists at Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago discovered a way to increase the efficiency of mature blood production in a dish.

29 Jun 2018

Review discusses complexity of immune-suppressive mechanisms in tumor milieu of cancers

Cancers control immune systems and evade immune detection using mediators consisting of immune checkpoint molecules and cellular systems associated with immune suppression.

29 Jun 2018

Scientists discover protein crucial for activating inflammation

Researchers from the University of Illinois at Chicago have identified a protein that is crucial for activating inflammation - both the good kind of inflammation that leads to healing wounds and fighting infection, as well as excessive inflammation where the immune system can damage tissues and organs.

27 Jun 2018

Research provides new target to help treat chemotherapy-induced diarrhea

Some 50 to 80 percent of cancer patients taking powerful chemotherapy drugs develop diarrhea, which can be severe and in some cases life-threatening.

27 Jun 2018

Targeting proteins in semen could prevent sexually transmitted spread of Ebola virus

Protein fragments, called amyloid fibrils, in human semen significantly increase Ebola virus infection and protect the virus against harsh environmental conditions such as heat and dehydration. Researchers from the Perelman School of Medicine at the University of Pennsylvania report these findings in a study published this week in the Proceedings of the National Academy of Sciences.

26 Jun 2018

Macrophage News and Research

Further Reading

Researchers create vaccine that protects against malaria in mouse models

Study demonstrates new therapeutic targets for inflammation-associated colon cancer

New clinical trial to evaluate virotherapy and immunotherapy combination for ovarian, colorectal cancers

Scientists pinpoint new therapeutic targets for inflammation-associated colon cancer

Study reveals how M. tuberculosis escapes death in macrophages

New TSPO-targeted PET imaging more fully evaluates extent of rheumatoid arthritis

Scientists discover new target to treat blood vessel damage in diabetes

Non-opioid drug shows promise for treating pain by targeting receptors on immune cells

Scientists take a deep dive into differences between Zika and dengue virus

Scientists use stem cells to uncover why the Zika virus is so infective

Seeing the Unexpected: Regulatory T Cells and Basophils

Scientists discover way to increase efficiency of mature blood production in a dish

Review discusses complexity of immune-suppressive mechanisms in tumor milieu of cancers

Scientists discover protein crucial for activating inflammation

Research provides new target to help treat chemotherapy-induced diarrhea

Targeting proteins in semen could prevent sexually transmitted spread of Ebola virus

New studies on fat cell filling, history of biochemistry, and ketogenic diet

New study shows how vitamin A effectively supports lung immunity against TB

Scientists discover protective mechanism against atherosclerosis

Mice study shows beneficial effect of MANF treatment on reversal of stroke-induced behavioral deficits

Microbiology eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo