Autoimmune Disease News and Research

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Autoimmune Disease is a condition in which the body recognizes its own tissues as foreign and directs an immune response against them.

Study suggests possible link between immune system and schizophrenia

Nancy Buccola, MSN, APRN, PMHCNS-BC, CNE, Assistant Professor of Clinical Nursing at LSU Health Sciences Center New Orleans School of Nursing, contributed samples used in a study reporting new locations of genetic material associated with schizophrenia and also suggesting a possible link between the immune system and schizophrenia.

23 Jul 2014

Thirteen scientists receive grant to identify new treatments, cure for psoriasis

Thirteen scientists received a total of $1.05 million in funding from the National Psoriasis Foundation for projects that aim to identify new treatments and a cure for psoriasis—an autoimmune disease that appears on the skin, affecting 7.5 million Americans—and psoriatic arthritis—an inflammatory arthritis that affects the joints and tendons, occurring in up to 30 percent of people with psoriasis.

16 Jul 2014

Virobay announces closing of expanded Series B second tranche financing

Virobay, Inc., a clinical stage pharmaceutical company with a platform of cathepsin protease inhibitors being developed for the treatment of neuropathic pain, autoimmune disease and fibrosis, today announced the closing of an expanded Series B second tranche financing of $8.0 million.

16 Jul 2014

Rigel initiates Phase 3 clinical program for fostamatinib in patients with ITP

Rigel Pharmaceuticals, Inc. today announced the initiation of a Phase 3 clinical program for its oral SYK inhibitor, fostamatinib, in patients with ITP (immune thrombocytopenic purpura).

16 Jul 2014

Researchers reveal molecular interplay between Roquin and RNA

The Roquin protein, discovered in 2005, controls T-cell activation and differentiation by regulating the expression of certain mRNAs. In doing so, it helps to guarantee immunological tolerance and prevents immune responses against the body's own structures that can lead to autoimmune disease.

16 Jul 2014

Hydroxychloroquine treatment not effective for primary Sjögren syndrome

Among patients with the systemic autoimmune disease primary Sjögren syndrome, use of hydroxychloroquine, the most frequently prescribed treatment for the disorder, did not improve symptoms during 24 weeks of treatment compared with placebo, according to a study in the July 16 issue of JAMA.

16 Jul 2014

Study to understand molecular interplay between Roquin and RNA to treat autoimmune diseases

Scientists at the Helmholtz Zentrum München, the Ludwig-Maximilians University of Munich (LMU) and the Technische Universität München (TUM) have moved an important step closer to understanding molecular mechanisms of autoimmune diseases.

14 Jul 2014

Portable, microchip-based test for diagnosing type-1 diabetes

An inexpensive, portable, microchip-based test for diagnosing type-1 diabetes could improve patient care worldwide and help researchers better understand the disease, according to the device's inventors at the Stanford University School of Medicine.

14 Jul 2014

National Psoriasis Foundation to double the number of researchers studying psoriasis

National Psoriasis Foundation will double the number of researchers studying psoriasis and psoriatic arthritis while also cutting in half the number of people who say these chronic conditions are a problem in their daily lives as part of its new five-year strategic plan and mission to cure psoriatic disease and improve the lives of those affected.

10 Jul 2014

Maternal inflammation in maternal blood linked with greater risk for schizophrenia in offspring

Maternal inflammation as indicated by the presence in maternal blood of early gestational C-reactive protein-an established inflammatory biomarker-appears to be associated with greater risk for schizophrenia in offspring, according to researchers at Columbia University's Mailman School of Public Health, Columbia University Medical Center, and the New York State Psychiatric Institute.

8 Jul 2014

Screening genetically susceptible infants can help detect celiac disease at a very early age

Physicians from the University of Colorado School of Medicine in collaboration with an international team of researchers have demonstrated that screening of genetically susceptible infants can lead to the diagnosis of celiac disease at a very early age.

3 Jul 2014

Researchers discover a way to restore corneal surface

A Boston-based scientific collaborative, led by Harvard Stem Cell Institute researchers, has discovered a way to collect the best cell type for regenerating a damaged cornea-the clear membrane that covers the pupil and directs light into the back of the eye.

3 Jul 2014

Wyatt Technology highlights protein-protein interactions study investigated by dynamic light scattering

Wyatt Technology Corporation, the world leader in absolute macromolecular characterization instrumentation, is pleased to highlight a study recently authored by Martin Skov Neergaard from the Faculty of Health and Medical Sciences at the University of Copenhagen, “Protein-Protein Interactions Investigated by DLS: Determination at High and Low Protein Concentration.”

From Waters | Wyatt Technology 1 Jul 2014

Researchers find unique cell type that can protect against uveitis

Researchers at the National Eye Institute (NEI) have found a unique cell type that, in tests on mice, can protect against uveitis—a group of inflammatory diseases that affect the eye and can cause vision loss.

1 Jul 2014

BioLineRx announces in-licensing of BL-1110 compound for treatment of neuropathic pain

BioLineRx Ltd., a clinical-stage biopharmaceutical company dedicated to identifying, in-licensing and developing promising therapeutic candidates, announced today it has in-licensed BL-1110, a novel compound for the treatment of neuropathic pain.

23 Jun 2014

Researchers find shared genetic link in autoimmune response among PV patients

Autoimmune disease occurs when the body's own natural defense system rebels against itself. One example is pemphigus vulgaris (PV), a blistering skin disease in which autoantibodies attack desmoglein 3 (Dsg3), the protein that binds together skin cells.

19 Jun 2014

Evolution of multiple sclerosis treatments: an interview with Mike Panzara, Head of MS & Neurology Clinical Development, Genzyme

The last 20 years have been defined by progress and innovation in the multiple sclerosis (MS) field, with now 10 approved treatment options available for people living with relapsing MS, the most common form of the disease.

17 Jun 2014

Discovery may lead to new treatments for common autoimmune diseases

Researchers at the University of Georgia report in the Journal of Biological Chemistry that an enzyme known as Tumor Progression Locus 2, or Tpl2, plays a key role in directing and regulating several important components of the body's immune system.

17 Jun 2014

Infliximab biosimilar CT-P13 improves disease activity in patients with Ankylosing Spondylitis

New data presented today at the European League Against Rheumatism Annual Congress (EULAR 2014) show that the newly-approved infliximab biosimilar CT-P13 achieves statistically similar improvements in disease activity, disability and mobility in patients with Ankylosing Spondylitis (AS) compared to its original reference product infliximab (INX).

13 Jun 2014

BRI researchers use tetramer technology to find T cells that drive rheumatoid arthritis

Researchers at Benaroya Research Institute at Virginia Mason used cutting-edge tetramer technology developed at BRI to find the T cells that drive rheumatoid arthritis (RA). "By using tetramer technology, we were able to examine whether T cells in people with rheumatoid arthritis were increased in number or were unique in other ways," says BRI Associate Director Jane Buckner, MD, who led the study with BRI Tetramer Core Laboratory Manager Eddie James, PhD.

12 Jun 2014

Autoimmune Disease News and Research

Further Reading

Study suggests possible link between immune system and schizophrenia

Thirteen scientists receive grant to identify new treatments, cure for psoriasis

Virobay announces closing of expanded Series B second tranche financing

Rigel initiates Phase 3 clinical program for fostamatinib in patients with ITP

Researchers reveal molecular interplay between Roquin and RNA

Hydroxychloroquine treatment not effective for primary Sjögren syndrome

Study to understand molecular interplay between Roquin and RNA to treat autoimmune diseases

Portable, microchip-based test for diagnosing type-1 diabetes

National Psoriasis Foundation to double the number of researchers studying psoriasis

Maternal inflammation in maternal blood linked with greater risk for schizophrenia in offspring

Screening genetically susceptible infants can help detect celiac disease at a very early age

Researchers discover a way to restore corneal surface

Wyatt Technology highlights protein-protein interactions study investigated by dynamic light scattering

Researchers find unique cell type that can protect against uveitis

BioLineRx announces in-licensing of BL-1110 compound for treatment of neuropathic pain

Researchers find shared genetic link in autoimmune response among PV patients

Evolution of multiple sclerosis treatments: an interview with Mike Panzara, Head of MS & Neurology Clinical Development, Genzyme

Discovery may lead to new treatments for common autoimmune diseases

Infliximab biosimilar CT-P13 improves disease activity in patients with Ankylosing Spondylitis

BRI researchers use tetramer technology to find T cells that drive rheumatoid arthritis

eBook: Integrated solutions for autoimmune disease drug development eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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