Lymph Node News and Research

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Lymph is clear or white fluid that travels through vessels, moves within tissues and work to keep all the parts of the body clean. After passing through the channels of the lymphatic system they drain into the lymph nodes. The lymph nodes act as filters along the lymphatic system. These nodes trap germs like bacteria, viruses, toxins as well as cancer cells and ensure that these are removed from the body.

Herceptin results "quite remarkable"

The targeted drug trastuzumab, or Herceptin, previously shown to prolong survival in advanced breast cancer, dramatically reduced the chances of recurrence in patients with early-stage disease when given for one year following standard chemotherapy.

19 Oct 2005

Majority of women with breast cancer do not need chemotherapy

Researchers are now saying that chemotherapy with drugs called aromatase inhibitors is unnecessary after lumpectomy, radiation and 5 years of Tamoxifen, for the vast majority of women with breast cancer.

19 Oct 2005

Patients with head and neck cancer may be spared the risk and expense of surgery by undergoing a CT scan

Researchers with the UF Shands Cancer Center have identified criteria doctors can use to evaluate CT scans four weeks after patients undergo initial treatment. If these criteria are met, there is a 94 percent likelihood a patient's lymph nodes are cancer free, said Stanley L. Liauw, M.D., a resident in radiation oncology.

18 Oct 2005

Evidence is mounting to link toxoplasmosis with schizophrenia

Keep pet cats inside, stop feeding strays, cook meat sufficiently and reconsider the way the veterinary profession and public health agencies think - and teach - about the zoonotic pathogen Toxoplasma gondii.

18 Oct 2005

Researchers shed light on a key molecular switch in T helper cells

Defects in immune system cells called T helper cells may lead to diseases characterized by a faulty inflammatory response such as autoimmunity and asthma. Understanding the molecular steps involved in how T helper cells mature may help researchers develop treatments for these diseases.

17 Oct 2005

Performing a sentinel node biopsy prior to mastectomy and reconstruction gives best results

Altering the standard step-by-step procedure that takes women facing a mastectomy from diagnosis to surgery to reconstruction can improve the process and help in determining if immediate reconstruction is the best course of action, according to new research from the University of North Carolina at Chapel Hill.

10 Oct 2005

Minimally invasive needle breast biopsies and sentinel node biopsies should be performed more routinely than they currently are

Physicians should strive to replace traditional, invasive procedures for diagnosing breast cancer with proven, less-invasive diagnostic methods, according to an international panel of breast cancer experts convened at the Keck School of Medicine of the University of Southern California.

9 Oct 2005

Americans' risk of dying from cancer continues to decline

The nation's leading cancer organizations report that Americans' risk of dying from cancer continues to decline and that the rate of new cancers is holding steady. The "Annual Report to the Nation on the Status of Cancer, 1975-2002," published in the Oct. 5, 2005, issue of the Journal of the National Cancer Institute, shows observed cancer death rates from all cancers combined dropped 1.1 percent per year from 1993 to 2002.

4 Oct 2005

Rapid weight gain between the ages of 25 and 40 doubles likelihood of prostate cancer recurrence

Men who gain weight rapidly between the ages of 25 and 40 are twice as likely to have recurrence of prostate cancer after surgery as men without rapid rates of weight gain, researchers from University of Texas M. D. Anderson Cancer Center reported in the October 1 issue of "Clinical Cancer Research."

4 Oct 2005

Compounds secreted by frog skin are potent blockers of HIV infection

The findings could lead to topical treatments for preventing HIV transmission, and they reinforce the value of preserving the Earth's biodiversity.

3 Oct 2005

Discovery of mechanism in the body that could lead to autoimmune diseases

Researchers at National Jewish Medical and Research Center have discovered a mechanism in the body that could lead to autoimmune diseases, such as lupus, rheumatoid arthritis, or diabetes.

3 Oct 2005

Steroids significantly reduce heart damage in children with Kawasaki's disease

When added to standard treatment, steroids significantly reduce the odds of developing heart damage in children with Kawasaki's disease, according to a study in the October issue of Pediatrics. These findings address a gap in knowledge.

3 Oct 2005

State-of-the-art treatment program increases survival from the aggressive uterine papillary serous carcinoma

"Our study defines a standard of care for this aggressive and growing form of uterine cancer," said Schwartz, who is also assistant chief of obstetrics and gynecology at Yale-New Haven Hospital. The procedure more accurately determines the complete stage and appropriate treatment and reduces the recurrence of the cancer.

26 Sep 2005

Surprising immune system cells discovery

Immune system cells are connected to each other by an extensive network of tiny tunnels that, like a building's hidden pneumatic tube system, are used to shoot signals to distant cells.

26 Sep 2005

Abnormal leakage of lymph fluid from the ruptured lymphatic vessels stimulates the accumulation of fat

Leaky lymphatic vessels are the leading cause of the adult onset obesity observed in a laboratory model developed by investigators at St. Jude Children's Research Hospital.

26 Sep 2005

Snail, a molecule normally important in embryonic development, can promote breast cancer recurrence

Using a recently developed mouse model of breast cancer, a team from the University of Pennsylvania School of Medicine has shown that Snail, a molecule normally important in embryonic development, can promote breast cancer recurrence.

20 Sep 2005

Does surgery induce angiogenesis in dormant breast cancer?

Analysis of breast-cancer relapse patterns from two independent databases provides indirect evidence for the theory that surgery to remove the primary tumor may initiate formation of a new blood supply (angiogenesis) in formerly dormant metastases, accounting for a pattern of early relapse in younger women.

12 Sep 2005

Combining radiation, chemotherapy and liver transplantation increases survival in bile duct cancer patients

A new treatment for patients with a type of bile duct cancer promises a greater chance at survival by combining radiation, chemotherapy and liver transplantation, Mayo Clinic physicians report in the September issue of the Annals of Surgery.

12 Sep 2005

Letrozole following tamoxifen may benefit women with breast cancer

Switching to the drug letrozole following 5 years of treatment with tamoxifen reduces the risk of hormone-dependent breast cancer recurrence, but not overall survival, among postmenopausal women, according to a new study in the September 7 issue of the Journal of the National Cancer Institute.

7 Sep 2005

Profile of immune cells in axillary lymph nodes predicts disease-free survival in breast cancer

Breast cancer often spreads through the lymph nodes in the arm pits (so-called axillary lymph nodes), and whether these lymph nodes are tumor-free or contain small metastases is an important factor in the decision of how aggressively to treat a patient.

6 Sep 2005

Lymph Node News and Research

Further Reading

Herceptin results "quite remarkable"

Majority of women with breast cancer do not need chemotherapy

Patients with head and neck cancer may be spared the risk and expense of surgery by undergoing a CT scan

Evidence is mounting to link toxoplasmosis with schizophrenia

Researchers shed light on a key molecular switch in T helper cells

Performing a sentinel node biopsy prior to mastectomy and reconstruction gives best results

Minimally invasive needle breast biopsies and sentinel node biopsies should be performed more routinely than they currently are

Americans' risk of dying from cancer continues to decline

Rapid weight gain between the ages of 25 and 40 doubles likelihood of prostate cancer recurrence

Compounds secreted by frog skin are potent blockers of HIV infection

Discovery of mechanism in the body that could lead to autoimmune diseases

Steroids significantly reduce heart damage in children with Kawasaki's disease

State-of-the-art treatment program increases survival from the aggressive uterine papillary serous carcinoma

Surprising immune system cells discovery

Abnormal leakage of lymph fluid from the ruptured lymphatic vessels stimulates the accumulation of fat

Snail, a molecule normally important in embryonic development, can promote breast cancer recurrence

Does surgery induce angiogenesis in dormant breast cancer?

Combining radiation, chemotherapy and liver transplantation increases survival in bile duct cancer patients

Letrozole following tamoxifen may benefit women with breast cancer

Profile of immune cells in axillary lymph nodes predicts disease-free survival in breast cancer

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