covid 19 News and Research

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Simplified glycan modeling of the SARS-CoV-2 spike protein

In a research paper recently uploaded to the preprint server bioRxiv* by Gecht et al. (August 4th, 2021), a new method of representing glycan conformers on static protein structures is explored, named GlycoSHIELD.

6 Aug 2021

Full dose anticoagulation with heparin improves outcomes for moderately ill COVID-19 patients

Collaborative international clinical trials testing full dose anticoagulation with heparin (a blood thinner) in both moderately ill and critically ill patients has found the treatment improves outcomes and reduces the need for vital organ support such as mechanical ventilation in moderately ill patients.

6 Aug 2021

Researchers identify genetic markers linked to COVID-19 severity and susceptibility

In collaboration with Northwestern Medicine investigators, an international multi-center study has identified genetic factors associated with SARS-CoV-2 infection and COVID-19 severity, according to findings published in Nature.

6 Aug 2021

Dialysis patients' response to COVID19 vaccine type

The researchers at Standford University evaluated the humoral vaccination response of 2,099 fully vaccinated patients undergoing dialysis.

5 Aug 2021

Multivalent nanobodies show improved neutralization activity against SARS-CoV-2

A state-of-the-art engineering approach toward improving the neutralizing activity of a cross-reactive nanobody, previously generated against the original SARS virus, showed it can be an attractive and viable option against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The study is published in the journal Advanced Therapeutics.

5 Aug 2021

New method for producing pseudotyped virus particles bearing spike protein of SARS-CoV-2

A new study discusses the development of an improved protocol based on cell lines that can consistently express S proteins.

5 Aug 2021

Activation of NLRP3 inflammasome by the N protein of SARS-CoV-2 to induce hyperinflammation

A new study has revealed the mechanism by which the SARS-CoV-2 N protein activates NLRP3 inflammasomes to induce hyperinflammation.

5 Aug 2021

New longevity metric: Average human lifespan reduced drastically by COVID-19

At its peak, COVID-19 drastically reduced the average human lifespan — by as much as 9 years in one U.S. state — according to a new longevity metric developed at UCLA.

5 Aug 2021

Nightlife industry joins national effort to drive COVID-19 vaccine uptake among young people

Leading figures of the nightlife industry - including venues Ministry of Sound and Heaven - have joined the national effort to get the country vaccinated as they urge young people to get a COVID-19 vaccine.

5 Aug 2021

Zoonotic disease surveillance must be integrated into health security intelligence systems, experts say

The surveillance of zoonotic diseases must be integrated into health security intelligence systems, if future pandemics are to be handled effectively, according to global health practitioners writing in the Journal of the Royal Society of Medicine.

5 Aug 2021

COVID vaccines generate antibodies in saliva

Researchers in the United States and Canada have conducted a study showing that the vaccines developed by Pfizer-BioNTech and Moderna to protect against coronavirus disease 2019 (COVID-19) generate local antibody responses in the salivary gland that are independent of the systemic immune response.

5 Aug 2021

Vaccination may protect against SARS-CoV-2 infection at the eye surface

Researchers in Australia have conducted a study showing that vaccination against coronavirus disease 2019 (COVID-19) induces key antibodies at the eye surface that may help to protect against the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

5 Aug 2021

COVID-19 vaccination offers significant protection for solid organ transplant recipients

In a Brief Communication, published July 29, 2021 in the journal Transplant Infectious Disease, a team of physician-scientists at University of California San Diego School of Medicine found that solid organ transplant recipients who were vaccinated experienced an almost 80 percent reduction in the incidence of symptomatic COVID-19 compared to unvaccinated counterparts during the same time.

5 Aug 2021

Scientists urge increased attention to persistent COVID-19 infections in immunocompromised people

In an article in the New England Journal of Medicine, scientists from Fred Hutchinson Cancer Research Center, Johns Hopkins Bloomberg School of Medicine, the U.S. Military HIV Research Program and the Institute for Global Health and Infectious Diseases at the University of North Carolina urged increased attention to persistent COVID-19 infections in immunocompromised people.

5 Aug 2021

Specific and sensitive biomarker in the blood predicts symptomatic COVID-19 infection

Researchers remain perplexed as to why some patients infected with SARS-CoV-2, the virus responsible for COVID-19, remain asymptomatic while other patients develop severe disease symptoms.

5 Aug 2021

Nine things parents should know about the Delta variant to keep children safe as schools reopen

Despite the rise in Delta variant cases, increased hospitalizations and reinstated mask mandates, many schools are set to reopen as early as next week.

5 Aug 2021

Using two different CRISPR enzymes to develop a faster and easier COVID-19 diagnostic test

Frequent, rapid testing for COVID-19 is critical to controlling the spread of outbreaks, especially as new, more transmissible variants emerge.

5 Aug 2021

Digital technology may become a standard tool for neuropsychological evaluations after COVID-19

The COVID-19 pandemic has significantly altered the delivery of health care including neuropsychological evaluations.

5 Aug 2021

KHN’s ‘What the Health?’: Delta blues

The U.S. is experiencing another surge of covid-19, particularly in Southern states where vaccination rates are generally lower than in other regions. But partisan fights rage on over what role government should play in trying to tamp down the highly contagious delta variant.

5 Aug 2021

A correlation study between time-from-vaccine and SARS-CoV-2 breakthrough infections

A new retrospective study compares the incidence rates of breakthrough infections between different time points at which individuals were vaccinated.

5 Aug 2021

covid 19 News and Research

Simplified glycan modeling of the SARS-CoV-2 spike protein

Full dose anticoagulation with heparin improves outcomes for moderately ill COVID-19 patients

Researchers identify genetic markers linked to COVID-19 severity and susceptibility

Dialysis patients' response to COVID19 vaccine type

Multivalent nanobodies show improved neutralization activity against SARS-CoV-2

New method for producing pseudotyped virus particles bearing spike protein of SARS-CoV-2

Activation of NLRP3 inflammasome by the N protein of SARS-CoV-2 to induce hyperinflammation

New longevity metric: Average human lifespan reduced drastically by COVID-19

Nightlife industry joins national effort to drive COVID-19 vaccine uptake among young people

Zoonotic disease surveillance must be integrated into health security intelligence systems, experts say

COVID vaccines generate antibodies in saliva

Vaccination may protect against SARS-CoV-2 infection at the eye surface

COVID-19 vaccination offers significant protection for solid organ transplant recipients

Scientists urge increased attention to persistent COVID-19 infections in immunocompromised people

Specific and sensitive biomarker in the blood predicts symptomatic COVID-19 infection

Nine things parents should know about the Delta variant to keep children safe as schools reopen

Using two different CRISPR enzymes to develop a faster and easier COVID-19 diagnostic test

Digital technology may become a standard tool for neuropsychological evaluations after COVID-19

KHN’s ‘What the Health?’: Delta blues

A correlation study between time-from-vaccine and SARS-CoV-2 breakthrough infections

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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