Hippocampus News and Research

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The hippocampus is a part of the forebrain, located in the medial temporal lobe. It belongs to the limbic system and plays major roles in short term memory and spatial navigation. Humans and other mammals have two hippocampi, one in each side of the brain.

New study reveals significance of critical periods in early-life learning on brain development

A new study on infantile memory formation in rats points to the importance of critical periods in early-life learning on functional development of the brain.

19 Jul 2016

Genes linked to Alzheimer's disease may show effects on the brain from childhood

A gene associated with Alzheimer's disease and recovery after brain injury may show its effects on the brain and thinking skills as early as childhood, according to a study published in the July 13, 2016, online issue of Neurology, the medical journal of the American Academy of Neurology.

14 Jul 2016

Western-style diet impairs memory inhibition leading to dietary excess

Obesity may ultimately be a disease of the brain, involving a progressive deterioration of various cognitive processes that influence eating.

12 Jul 2016

Scientists reveal how manipulating novel target in the brain could lead to new therapies for depression

Northwestern Medicine scientists have shown how manipulating a novel target in the brain using gene therapy could lead to new treatments for depression.

12 Jul 2016

Extra-coding RNA modulates neuronal DNA methylation patterns

The creation of memories in the brain involves addition or removal of methyl groups at precise spots on chromosomal DNA. But what controls the careful targeting of these neuronal DNA methylation dynamics?

8 Jul 2016

Hippocampal inflammation linked to depressive symptoms in patients with multiple sclerosis

Patients with multiple sclerosis have higher rates of depression than the general population, including people with other life-long disabling diseases. Symptoms of multiple sclerosis arise from an abnormal response of the body's immune system.

7 Jul 2016

Genetic risk score may help detect Alzheimer's disease risk in healthy young adults

New research shows that a genetic risk score may detect those at higher risk for Alzheimer's disease long before symptoms appear—even possibly in healthy young adults, according to a study published in the July 6, 2016, online issue of Neurology, the medical journal of the American Academy of Neurology.

7 Jul 2016

Scientists reveal how new adult-born neurons evolve in olfactory bulb of mice

Scientists from the Institut Pasteur and the CNRS were able to make real-time observations over a period of several months that reveal how new adult-born neurons are formed and evolve in the olfactory bulb of mice.

4 Jul 2016

Researchers uncover how dysfunction of brain circuit may contribute to memory loss

Two interconnected brain areas - the hippocampus and the entorhinal cortex - help us to know where we are and to remember it later.

30 Jun 2016

Study links dopamine D2 receptor to long-term episodic memory

A European study led by Umea University Professor Lars Nyberg, has shown that the dopamine D2 receptor is linked to the long-term episodic memory, which function often reduces with age and due to dementia.

29 Jun 2016

Why does appetite loss occur during illness? An interview with Prof. Conti and Prof. Francesconi

Appetite, as a word, come from the Latin appetitus, meaning "desire for.” Therefore, appetite can be defined as a pleasurable sensation or the desire to eat. This sensation is coordinated by several brain areas associated with reward processing such amygdala, hippocampus, ventral pallidum, nucleus accumbens and striatum, and others.

28 Jun 2016

Positive environment can reverse trauma-related behavioral alterations in mice

Traumatic experiences in childhood increase the risk of developing behavioral and psychiatric disorders later in life. It is also known that the consequences of a trauma can likewise be observed in the children of people affected even if those children have themselves not experienced any trauma.

24 Jun 2016

Study shows skill-related memory persists in amnesia patients

She no longer recognizes a Van Gogh, but can tell you how to prepare a watercolor palette.

23 Jun 2016

Study finds link between pontosubicular necrosis and placental pathology

Pediatric and Developmental Pathology – A stillbirth occurs when a baby is born without any signs of life. Placental pathology is found to be related to the cause of death in a significant number of pregnancies that result in stillbirth

20 Jun 2016

Researchers aim to explore whether cell transplantation can treat temporal lobe epilepsy

Researchers at Cardiff University's School of Medicine are about to explore whether it's possible to treat human temporal lobe epilepsy (TLE) by transplanting immature neuron cells into the brain.

16 Jun 2016

Researchers find new method to replicate one of earliest changes in Alzheimer’s disease

Researchers at the Babraham Institute have found a way to replicate one of the earliest changes in Alzheimer's disease in a dish. This means that it should now be possible to find out a lot more about why it happens - and how to stop it. The new findings are published in the journal Molecular Neurodegeneration and supported by the charity Alzheimer's Research UK.

15 Jun 2016

New technique may help replace brain cells, restore memory

Although brains—even adult brains—are far more malleable than we used to think, they are eventually subject to age-related illnesses, like dementia, and loss of cognitive function.

15 Jun 2016

NMNAT2 enzyme may help protect against debilitating effects of neurodegenerative disorders

A study led by biomedical researchers at Indiana University has found evidence that an enzyme known as NMNAT2 may help protect against the debilitating effects of certain degenerative brain diseases, including Alzheimer's.

3 Jun 2016

Researchers shed more light on how brain rhythms organize memories across time

Just as members of an orchestra need a conductor to stay on tempo, neurons in the brain need well-timed waves of activity to organize memories across time. In the hippocampus--the brain's memory center--temporal ordering of the neural code is important for building a mental map of where you've been, where you are, and where you are going.

31 May 2016

Miniature microscope helps neuroscientists identify how the brain links different memories over time

Using a miniature microscope that opens a window into the brain, UCLA neuroscientists have identified in mice how the brain links different memories over time. While aging weakens these connections, the team devised a way for the middle-aged brain to reconnect separate memories.

24 May 2016