Immune System News and Research

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Mitochondrial dysfunction drives cerebellar damage in multiple sclerosis

Multiple sclerosis (MS) affects an estimated 2.3 million people worldwide. Approximately 80% of people with MS have inflammation in the cerebellum, the part of the brain that helps control movement and balance, potentially leading to tremors, poor coordination, and trouble with motor control.

16 Jun 2025

Paper-based devices show high accuracy in detecting asymptomatic malaria

Devices made with cheap strips of paper have outperformed two other testing methods in detecting malaria infection in asymptomatic people in Ghana – a diagnostic advance that could accelerate efforts to eliminate the disease, researchers say.

16 Jun 2025

Deep B cell depletion offers new hope for rheumatologic and musculoskeletal diseases

CD19-CAR T-cell treatment is a novel option of deep B cell depletion with promising results across different rheumatologic and musculoskeletal diseases (RMD).

15 Jun 2025

Short peptides show promise in blocking breast cancer metastasis

A surgeon can excise breast cancer from the body, but even the most skilled scalpel may not be able to remove every cell - especially when the cells have spread from the original disease site elsewhere in the body.

13 Jun 2025

Low-dose vitamin D supplements can increase effectiveness of chemotherapy in breast cancer patients

A study conducted at the Botucatu School of Medicine at São Paulo State University (FMB-UNESP) in Brazil has shown that low-dose vitamin D supplementation can increase the effectiveness of chemotherapy treatment in women with breast cancer.

13 Jun 2025

Engineered lymph node model advances human immune system research

Scientists with the Fralin Biomedical Research Institute at VTC have created an engineered model of the supportive tissue found within a lymph node to study human health.

12 Jun 2025

Lab-grown mini intestines reveal how Shigella infects human gut

Thanks to lab-grown miniature intestines, researchers at Uppsala University have successfully mapped how aggressive Shigella bacteria infect the human gut.

12 Jun 2025

Cholesterol shields cancer cells from heat treatment in hyperthermia therapy

Hyperthermia, a cancer treatment using controlled heat to kill tumor cells, shows promise but faces limitations due to some tumor cells' unexpected heat resistance.

12 Jun 2025

Lower oral microbiome diversity linked to higher depression symptoms

A rich and varied mix of microbes in the mouth, particularly bacteria, is not only important for our oral health, but may hold clues for other conditions.

12 Jun 2025

Exercise and omega-3 reduce oral inflammation in animal study

A study published in the journal Scientific Reports indicates that physical exercise combined with omega-3 supplementation considerably improves the immune response and reduces the severity of chronic apical periodontitis.

11 Jun 2025

New cancer vaccine shows promise against deadly pancreatic tumors

Pancreatic cancer has a five-year survival rate of just 13%, making it the deadliest cancer, according to the American Cancer Society.

11 Jun 2025

Difficult childhood experiences linked to increased risk of endometriosis later in life

A new study from Karolinska Institutet involving over a million women links difficult childhood experiences to the risk of being diagnosed with endometriosis later in life.

11 Jun 2025

Targeting metabolic reprogramming in breast cancer treatment

Breast cancer remains the most prevalent malignancy among women worldwide, posing a critical challenge to global health.

11 Jun 2025

Italian researcher sheds light on the lasting psychiatric impact of childhood trauma

In a revealing Genomic Press Interview published today in Brain Medicine, Sara Poletti, PhD, senior researcher at IRCCS Ospedale San Raffaele Milan, illuminates the profound connections between childhood adversity and lifelong vulnerability to psychiatric disorders through persistent neuroinflammation pathways and alterations in brain structure.

11 Jun 2025

Eva1 targeted CAR T cells successfully eliminate tumors in preclinical study

CAR-T cells are specialized immune cells genetically modified to recognize and attack cancer cells. Researchers at Nagoya University in Japan and their collaborators have developed new CAR-T cells to target malignant tumors.

11 Jun 2025

Study reveals a unique vulnerability in melanoma patients with neurofibromin 1 mutations

Increased activity in a specific biological pathway may explain why many patients with a deadly form of skin cancer do not respond to the latest cancer treatments, a new study shows.

10 Jun 2025

COVID boosters do not harm T-cell function in the vulnerable

Findings indicate that frequent COVID-19 booster shots do not weaken T-cell responses, alleviating concerns for vulnerable groups facing new variants.

9 Jun 2025

Study reveals mechanisms behind antibiotic-related immune disruptions in infants

In 2017, scientists at Cincinnati Children's revealed that using antibiotics to protect newborns from dangerous infections often comes with a long-term consequence-a permanently underdeveloped immune system that can make children prone to poor outcomes from future lung infections.

9 Jun 2025

Glycan mapping reveals what keeps the vaginal microbiome healthy

Glycan-bacteria binding profiles in the vaginal microbiome provide insights into reproductive health, highlighting targets for infection prevention strategies.

9 Jun 2025

Study offers new insights into how the body clears dead cells during stress

A new study from The University of Texas at Arlington details a novel strategy for how the body clears out dead cells during stress, revealing unexpected roles for well-known stress-response genes-a discovery that could help scientists better understand diseases affecting the immune system, brain and metabolism.

9 Jun 2025