Brain News and Research

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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

Study explains future ethical implications of brain organoid research

Stem cell research has allowed medicine to go places that were once science fiction. Using stem cells, scientists have manufactured heart cells, brain cells and other cell types that they are now transplanting into patients as a form of cell therapy.

9 Apr 2021

Study: Age-related changes in brain stem cells are more pronounced in male animals

Ageing and age-related brain disease do not affect women and men in the same way. The adult brain constantly generates new brain cells called neurons from stem cells, a process called neurogenesis. This process is important for learning and cognitive function which declines as the brain ages.

9 Apr 2021

Study reveals link between changes of neuronal activities and dyskinesia

Many people with Parkinson's disease develop abnormal movements called L-DOPA induced dyskinesia, a major side effect of long-term medication. The mechanism underlying this side effect has been unknown. In this study, researchers have revealed relation between changes of neuronal activities and dyskinesia.

9 Apr 2021

Supportive partners can buffer the detrimental effects of depression, external stress

Having a responsive, supportive partner minimizes the negative impacts of an individual's depression or external stress on their romantic relationship, according to research by a University of Massachusetts Amherst social psychologist.

9 Apr 2021

Pig brain atlas gives a more precise view of human brain

When scientists need to understand the effects of new infant formula ingredients on brain development, it's rarely possible for them to carry out initial safety studies with human subjects.

8 Apr 2021

Accelerated cellular aging in depressed individuals associated with increased mortality risk

Cells from healthy individuals with major depressive disorder were found to have higher than expected rates of methylation at specific sites on their DNA, when compared to cells from healthy individuals without MDD, according to a study by a multidisciplinary team of Walter Reed Army Institute of Research and University of California San Francisco scientists, in collaboration with others.

8 Apr 2021

Powerful algorithms can 'predict' the biological language of cancer and Alzheimer's

Powerful algorithms used by Netflix, Amazon and Facebook can 'predict' the biological language of cancer and neurodegenerative diseases like Alzheimer's, scientists have found.

8 Apr 2021

Researchers identify nonelectrical cells that transition the brain from plasticity to stability

Researchers exploring the developing central nervous system of fruit flies have identified nonelectrical cells that transition the brain from highly plastic into a less moldable, mature state.

8 Apr 2021

Full assembly of human chromosome 8 reveals novel genes, disease risks

The full assembly of human chromosome 8 is reported this week in Nature. While on the outside this chromosome looks typical, being neither short nor long or distinctive, its DNA content and arrangement are of interest in primate and human evolution, in several immune and developmental disorders, and in chromosome sequencing structure and function generally.

8 Apr 2021

Real-time imaging shines light on the coordination of neural stem cell activation

In all adult vertebrates, neural stem cells can be recruited to produce new neurons in the brain. However, little is known about these so-called "activation" processes.

8 Apr 2021

Study offers a promising blood test for depression, bipolar disorder

Worldwide, 1 in 4 people will suffer from a depressive episode in their lifetime. While current diagnosis and treatment approaches are largely trial and error, a breakthrough study by Indiana University School of Medicine researchers sheds new light on the biological basis of mood disorders, and offers a promising blood test aimed at a precision medicine approach to treatment.

8 Apr 2021

Mutations to autism-associated gene cause a cascade of problems in developing mouse brains

Damage to the autism-associated gene Dyrk1a, sets off a cascade of problems in developing mouse brains, resulting in abnormal growth-factor signaling, undergrowth of neurons, smaller-than-average brain size, and, eventually, autism-like behaviors, a new study from Scripps Research, Florida, finds.

8 Apr 2021

Phase 3 clinical trial tests new treatment for brain metastases from small-cell lung cancer

A new phase 3 randomized clinical trial overseen by CU Cancer Center member Chad Rusthoven, MD, and Vinai Gondi, MD, from Northwestern University, is testing whether a new treatment approach could result in improved outcomes for patients with small cell lung cancer (SCLC) that has spread to the brain.

8 Apr 2021

Study links chronic sinus inflammation with alterations in brain activity

The millions of people who have chronic sinusitis deal not only with stuffy noses and headaches, they also commonly struggle to focus, and experience depression and other symptoms that implicate the brain's involvement in their illness.

8 Apr 2021

Novel mRNA delivery system produces a therapeutic protein that protects neurons from ischemia

A lack of oxygen to brain tissue--known as ischemia--leads to the death of neurons, which results in stroke. Despite considerable research, there are currently no treatments that successfully prevent neuronal death.

8 Apr 2021

Microrna-29 molecule controls brain maturation in mammals

A team led by scientists at the UNC School of Medicine identified a molecule called microRNA-29 as a powerful controller of brain maturation in mammals. Deleting microRNA-29 in mice caused problems very similar to those seen in autism, epilepsy, and other neurodevelopmental conditions.

8 Apr 2021

Leaky gut and microbial dysbiosis could contribute to cytokine storm in severely ill COVID-19 cases

The gut is a well-established route of infection and target for viral damage by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent for COVID-19. This is supported by the clinical observation that about half of COVID-19 patients exhibit gastrointestinal (GI) symptoms.

8 Apr 2021

Anticoagulation should not be regarded as primary cause of intracerebral haemorrhages, finds study

Cardiovascular diseases are usually complex and affect multiple organs simultaneously. Treatments for vascular diseases in the brain may therefore have implications for the treatment of cardiac diseases. It is therefore important to understand the respective causes and effects.

8 Apr 2021

Study: 1 in 10 people still has moderate to severe symptoms after mild COVID-19

Eight months after mild COVID-19, one in ten people still has at least one moderate to severe symptom that is perceived as having a negative impact on their work, social or home life. The most common long-term symptoms are a loss of smell and taste and fatigue.

8 Apr 2021

Study shows how signal propagation circuit is modulated by attention

To effectively perform any daily task, the human brain needs to process information from the outside world using various cognitive functions. This cognitive processing passes through a dense interconnected network of cells whose physiology is specialized.

8 Apr 2021

Brain News and Research

Further Reading

Study explains future ethical implications of brain organoid research

Study: Age-related changes in brain stem cells are more pronounced in male animals

Study reveals link between changes of neuronal activities and dyskinesia

Supportive partners can buffer the detrimental effects of depression, external stress

Pig brain atlas gives a more precise view of human brain

Accelerated cellular aging in depressed individuals associated with increased mortality risk

Powerful algorithms can 'predict' the biological language of cancer and Alzheimer's

Researchers identify nonelectrical cells that transition the brain from plasticity to stability

Full assembly of human chromosome 8 reveals novel genes, disease risks

Real-time imaging shines light on the coordination of neural stem cell activation

Study offers a promising blood test for depression, bipolar disorder

Mutations to autism-associated gene cause a cascade of problems in developing mouse brains

Phase 3 clinical trial tests new treatment for brain metastases from small-cell lung cancer

Study links chronic sinus inflammation with alterations in brain activity

Novel mRNA delivery system produces a therapeutic protein that protects neurons from ischemia

Microrna-29 molecule controls brain maturation in mammals

Leaky gut and microbial dysbiosis could contribute to cytokine storm in severely ill COVID-19 cases

Anticoagulation should not be regarded as primary cause of intracerebral haemorrhages, finds study

Study: 1 in 10 people still has moderate to severe symptoms after mild COVID-19

Study shows how signal propagation circuit is modulated by attention

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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