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Translating COVID-19 into sound

News-Medical speaks to Professor Markus Buehler about his research into COVID-19 and how he has translated the SARS-CoV-2 virus into sound.

14 Apr 2020

Technologies converge on interacting surfaces in protein complexes

Researchers have fine-tuned a method to pinpoint surfaces within interacting large multi-protein complexes.

14 Apr 2020

Tumors commandeer cell death pathway to avoid immune system attack after radiation

Cancer cells avoid an immune system attack after radiation by commandeering a cell signaling pathway that helps dying cells avoid triggering an immune response, a new study led by UTSW scientists suggests.

13 Apr 2020

Skoltech scientists propose new method to make doping tests quicker

Skoltech scientists and their colleagues proposed a way to simplify the search for traces of medicines, narcotic substances and sports doping drugs in human biological samples by performing two additional tests with the search domain reduced tenfold.

13 Apr 2020

Ebola drug effective against key enzyme of coronavirus that causes COVID-19

Scientists at the University of Alberta have shown that the drug remdesivir is highly effective in stopping the replication mechanism of the coronavirus that causes COVID-19, according to new research published today in the Journal of Biological Chemistry.

13 Apr 2020

Toxic cell atlas can guide discovery of new drugs for neurodegeneration

A common thread in many inflammatory and neurodegenerative diseases, including multiple sclerosis (MS), is damage caused by oxidative stress. Oxidative stress occurs when cells produce toxic substances known as reactive oxygen species, which are damaging nerve cells and other cells in the body.

13 Apr 2020

Could DPP4 inhibitors help treat COVID-19?

Researchers and clinicians are scrambling to find ways to combat COVID-19, including new therapeutics and eventually a vaccine.

13 Apr 2020

Super-charging production of drugs for COVID-19

Researchers are ramping up production of a promising drug that has proven effective in obliterating SARS-CoV in cellular cultures. The team hopes that the drug might also be effective in the fight against SARS's close genetic cousin, the novel coronavirus (COVID-19).

13 Apr 2020

CRISPR may help in kidney-transplants by detecting viruses

An exciting new study published in the journal Nature Biomedical Engineering in April 2020 reports excellent results with a new test for two common viruses that infect kidney transplant patients. The levels of these viruses shoot up during the acute phase of rejection.

13 Apr 2020

UB biologist investigates how foxglove plants create medicinal compounds

Foxglove plants, found in many gardens, are known for the showers of bell-shaped flowers they produce.

13 Apr 2020

New insights into the building blocks of periodontitis

Porphyromonas gingivalis is a major bacterial pathogen which leads to periodontitis also known as gum disease. In Japan, 80% of adults aged 35 and over suffer from this disease. What's more, P. gingivalis has also been linked to rheumatoid arthritis, cardiovascular disease, pancreatic cancer, and even Alzheimer's disease.

13 Apr 2020

Chinese scientists report high-resolution crystal structure of COVID-19 main protease

A team of Chinese scientists has reported the high-resolution crystal structure of the main protease (Mpro) of the COVID-19 virus and has identified drugs that may hold promise in combating the virus.

13 Apr 2020

Exercise enhances muscle-repair capabilities in old mice, Stanford study shows

A nightly jaunt on the exercise wheel enhances muscle-repair capabilities in old mice, according to a new study by researchers at Stanford School of Medicine.

13 Apr 2020

Cost of ‘repurposing’ existing drugs to treat COVID-19

The paper looks at repurposed drugs that might demonstrate efficacy against COVID-19, and if they could be manufactured profitably at very low costs to ensure affordable access to vital treatments for COVID-19 at low prices globally.

13 Apr 2020

Stanford scientists find gene variant that staves off Alzheimer's in some people

Stanford Medicine researchers have found a gene variant that protects carriers of another gene variant, ApoE4, from developing Alzheimer’s disease — the first demonstration of that beneficial effect.

13 Apr 2020

Rockefeller and SNF announce $3 million expansion of partnership for COVID-19 research

The Rockefeller University and the Stavros Niarchos Foundation today announced a $3 million expansion of their longstanding partnership for research and medicine, bolstering Rockefeller's round-the-clock research initiatives related to COVID-19 and the SARS-CoV-2 virus that causes it.

13 Apr 2020

Intermountain Healthcare and University of Utah Health launch two COVID-19 clinical trials

Researchers from Intermountain Healthcare and University of Utah Health in Salt Lake City have launched two vital clinical trials to test the effectiveness and safety of two drugs - hydroxychloroquine and azithromycin - to treat patients with COVID-19.

13 Apr 2020

Chemists identify a drug to rescue winter depression-like behavior

A group of animal biologists and chemists at the Institute of Transformative Bio-Molecules, Nagoya University, has used a chemical genomics approach to explore the underlying mechanism of winter depression-like behavior and identified a drug that rescues winter depression-like behavior in medaka fish.

13 Apr 2020