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Lopinavir and ritonavir drug combo tested in severe COVID-19

Researchers from China and the United Kingdom have collaborated to conduct a clinical trial looking at the efficacy of a combination of two anti-HIV drugs lopinavir and ritonavir to combat severe cases of COVID-19. Their study titled, “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe COVID-19,” was published in the latest issue of the New England Journal of Medicine (NEJM).

19 Mar 2020

Research aimed at increasing shelf life of radiation drugs offers hope for cancer patients

People with hard-to-reach cancers in the kidney, gut and prostate will have improved hope for early diagnosis and treatment with new research aimed at increasing the shelf life of revolutionary radiation drugs.

19 Mar 2020

Revolutionary technology could help identify more effective cancer drug combinations

A revolutionary new technology has been applied to reveal the inner workings of individual cancer cells - potentially identifying more effective treatment combinations for people with cancer.

19 Mar 2020

Study helps predict which ovarian cancer patients will not benefit from immune-PARP combo

In patients with advanced ovarian cancer, a combination of drugs known as immune checkpoint inhibitors and PARP inhibitors can produce powerful remissions, clinical trials have shown, but up until now investigators haven't been able to predict which patients won't benefit from the treatment and should explore other options.

19 Mar 2020

Study paves way for identifying ovarian cancer patients who will not benefit from combination therapy

A study suggests it may be possible to identify those who will not benefit from drug combination for advanced ovarian cancer.

19 Mar 2020

First-of-its kind study identifies the hidden costs of avoidable deficiencies in heart failure

Today, the first investigation of its kind, published in Open Heart, has identified the hidden costs of heart failure (HF) due to under-managed but treatable iron deficiency (ID) and iron deficiency anaemia (IDA). Leading UK clinicians assessed the one-year data of around 80,000 people with HF as part of the analysis.

19 Mar 2020

Bacteria-trapping protein may contribute to breast cancer metastasis

The protein peptidyl arginine deiminase 4 (PAD4), which enables some immune cells to trap bacteria, promoted breast cancer metastasis in mice when expressed in cancer cells, according to data published in Molecular Cancer Research, a journal of the American Association for Cancer Research.

19 Mar 2020

Consistent guidelines for treating urinary tract infections

They are among the most common ailments for those residing at post-acute and long-term care (PALTC) centers, yet diagnosing and managing urinary tract infections (UTIs) remains a challenging prospect for caregivers at these facilities.

19 Mar 2020

Cryo-electron microscopy helps visualize ball-and-chain inactivation of ion channels

Ion channels, which allow potassium and sodium ions to flow in and out of cells, are crucial in neuronal 'firing' in the central nervous system and for brain and heart function.

19 Mar 2020

Identification of 'Hodor' in the gut lining highlights potential way to curb mosquito populations

The identification of an insect-specific metal-sensing receptor in the gut lining highlights a possible new way to curb populations of disease-transmitting insects such as mosquitoes.

18 Mar 2020

Singapore researchers find common therapeutic vulnerability for a deadly blood cancer

CML is a blood cancer that can be controlled by continuously taking an expensive type of medicine called a tyrosine kinase inhibitor (TKI). In almost all patients, stopping TKI treatment results in recurrence of CML.

18 Mar 2020

Viewpoint: Could infectious pathogens play a role in Alzheimer's disease?

For researchers investigating Alzheimer's Disease (AD), a devastating neurodegenerative illness afflicting close to 6 million Americans, it is the best and worst of times.

18 Mar 2020

Key COVID-19 information for gastroenterologists and patients with digestive conditions

A paper published today in Clinical Gastroenterology and Hepatology by clinicians at Icahn School of Medicine at Mount Sinai outlines key information gastroenterologists and patients with chronic digestive conditions need to know about COVID-19, or coronavirus.

18 Mar 2020

Why is the tobacco industry supporting wider access to medical cannabis?

A new study published in the BMJ reveals disturbing connections between organizations and groups that are lobbying for broader access to medical cannabis and those who are fighting for the legalization of recreational cannabis. This raises questions as to the reasons behind the industry’s support for measures that will make it easier for patients to gain access to medical cannabis – is it because of the knowledge that by so doing, they will also be able to market the drug for recreational use in the UK?

18 Mar 2020

Listening to music for 30 minutes a day provides benefits after heart attack

Listening to music can be enjoyable, but is it also good for your heart? Patients who suffered episodes of chest pain soon after a heart attack, known as early post-infarction angina, had significantly lower levels of anxiety and pain if they listened to music for 30 minutes a day, according to a study presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology

18 Mar 2020

People with a cancer history have increased risk of developing atrial fibrillation

People with a history of cancer have an over two-fold risk of developing atrial fibrillation (AFib), the most common heart rhythm disorder, compared to the general population, according to research presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology

18 Mar 2020

Ibuprofen could increase risk of coronavirus complications

The UK’s National Health Service says that people who have COVID-19 and are self-quarantined should rest and drink plenty of fluids. So far, so good. However, it goes on to advise that they take paracetamol or ibuprofen to keep down fever and pain.

17 Mar 2020

Engineered botox more effective

A new study reports on an engineered botulinum neurotoxin (botox) that is more effective as well as safer to use in various medical procedures. The study was published in March 2020 in the open-access journal PLOS Biology.

17 Mar 2020

Bentham Science announces new journal to cover latest research on coronaviruses

Bentham Science announces a new journal, "Coronaviruses" to cover the latest research on coronaviruses, related outbreak and the methods employed to treat coronavirus infections.

17 Mar 2020

Scientists develop single-step method to produce water-soluble fullerene compounds for medicine

Scientists from the Skoltech Center for Energy Science and Technology and the Institute for Problems of Chemical Physics of Russian Academy of Sciences in collaboration with researchers from the Catholic University of Leuven developed a single-step method to obtain water-soluble fullerene compounds with remarkable biological properties, such as the ability to effectively suppress the human immunodeficiency virus

17 Mar 2020

Drugs News and Research

Lopinavir and ritonavir drug combo tested in severe COVID-19

Research aimed at increasing shelf life of radiation drugs offers hope for cancer patients

Revolutionary technology could help identify more effective cancer drug combinations

Study helps predict which ovarian cancer patients will not benefit from immune-PARP combo

Study paves way for identifying ovarian cancer patients who will not benefit from combination therapy

First-of-its kind study identifies the hidden costs of avoidable deficiencies in heart failure

Bacteria-trapping protein may contribute to breast cancer metastasis

Consistent guidelines for treating urinary tract infections

Cryo-electron microscopy helps visualize ball-and-chain inactivation of ion channels

Identification of 'Hodor' in the gut lining highlights potential way to curb mosquito populations

Singapore researchers find common therapeutic vulnerability for a deadly blood cancer

Viewpoint: Could infectious pathogens play a role in Alzheimer's disease?

Key COVID-19 information for gastroenterologists and patients with digestive conditions

Why is the tobacco industry supporting wider access to medical cannabis?

Listening to music for 30 minutes a day provides benefits after heart attack

People with a cancer history have increased risk of developing atrial fibrillation

Ibuprofen could increase risk of coronavirus complications

Engineered botox more effective

Bentham Science announces new journal to cover latest research on coronaviruses

Scientists develop single-step method to produce water-soluble fullerene compounds for medicine

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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