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Genetic inheritance and life experience leave distinct epigenetic marks in immune cells

The COVID-19 pandemic gave us tremendous perspective on how wildly symptoms and outcomes can vary between patients experiencing the same infection.

29 Jan 2026

Study reveals a link between oral microbiota and cognitive performance in schizophrenia

An association between oral microbiota and cognitive performance in schizophrenia has been reported by researchers at Science Tokyo.

29 Jan 2026

Genetic variants associated with rare inherited growth disorder identified in two prehistoric individuals

Researchers led by the University of Vienna and Liège University Hospital Centre have identified genetic variants associated with a rare inherited growth disorder in two prehistoric individuals who lived more than 12,000 years ago.

29 Jan 2026

Study uncovers genes and proteins likely to play a causal role in Type 2 diabetes

An international study co-led by researchers from the University of Massachusetts Amherst and Helmholtz Munich in Germany has uncovered hundreds of genes and proteins likely to play a causal role in Type 2 diabetes, many of which would have been missed by studies relying on blood samples alone.

29 Jan 2026

Sharing thoughts and feelings may enhance recovery in stroke survivors

Stroke survivors who were uncomfortable sharing their thoughts and feelings about their condition and future had slower physical and cognitive recovery after their stroke, according to a preliminary study to be presented at the American Stroke Association's International Stroke Conference 2026.

29 Jan 2026

Umbilical cord blood markers may predict future type 1 diabetes

One day, there could be a new test to screen for type 1 diabetes, now that scientists have found markers in the blood of the umbilical cords of children who were later diagnosed with the disease.

29 Jan 2026

How DNA and life experiences leave distinct marks on the human immune system

Using single-cell epigenomic profiling of immune cells from 110 individuals, researchers show that genetic variation and environmental exposures shape the human immune system through distinct DNA methylation mechanisms. Genetic effects concentrate within gene bodies of memory cells, while environmental exposures primarily remodel regulatory regions in naive immune cells.

28 Jan 2026

Zebrafish can play a decisive role in clinical interpretation of spinal muscular atrophy

The tiny zebrafish is helping researchers rapidly determine whether a newborn's genetic mutation is likely to cause spinal muscular atrophy (SMA), one of the leading causes of infant mortality worldwide.

28 Jan 2026

Redefining early detection for type 1 diabetes

Researchers have identified a protein pattern that, already at birth, looks markedly different in those who later go on to develop type 1 diabetes. The findings show that a combination of several factors during pregnancy increases the risk of the child later developing the disease. The study is published in Nature Communications and was led by researchers at Linköping University, Sweden, and the University of Florida, USA.

28 Jan 2026

New discovery may aid in early detection of rare genetic disease

Virginia Tech researchers discovered an indication hidden in the brain that may help doctors identify children suffering from a rare genetic disease earlier. Their findings were published recently in EMBO Molecular Medicine.

28 Jan 2026

Following the EAT-Lancet diet lowers chronic kidney disease risk

Research shows the EAT-Lancet diet may lower chronic kidney disease risk, emphasizing the importance of diet quality and personalized nutrition in prevention.

28 Jan 2026

Research finds scientists view ELNs as “glorified filing cabinets,” driving frustration, duplication and shadow AI use

Sapio Sciences, the science-aware™ AI lab informatics platform, today announced the results of new research examining scientists’ sentiment around electronic lab notebooks (ELNs) and AI tools in modern laboratory environments.

From Sapio Sciences 27 Jan 2026

Study isolates mania-specific genetic architecture in bipolar disorder

Researchers at King's College London and the University of Florence have, for the first time, identified the specific genetic blueprint of mania, the defining feature of bipolar disorder.

27 Jan 2026

First topical CRISPR gene therapy corrects disease-causing mutations in human skin

Gene-editing tools like CRISPR have unlocked new treatments for previously uncurable diseases. Now, researchers at the University of British Columbia are extending those possibilities to the skin for the first time.

27 Jan 2026

Antibody-producing plasma cells shape effectiveness of PD-1 immunotherapy

Scientists at the Icahn School of Medicine at Mount Sinai have identified an important immune response that helps explain why some cancer patients benefit from immunotherapy while others do not.

27 Jan 2026

Tracking antibiotic resistance across environmental systems using advanced metagenomic tools

Antibiotic resistance is often framed as a hospital problem, but a growing body of evidence shows that the environment plays an equally critical role in the global spread of drug resistant bacteria.

27 Jan 2026

Gut problems may shape Parkinson’s disease progression through the gut-brain axis

This narrative review examines how gastrointestinal dysfunction, gut dysbiosis, and altered gut-brain axis signaling are closely associated with the onset and progression of Parkinson’s disease. It synthesizes evidence supporting a possible bottom-up disease model while highlighting integrative, gut-targeted strategies as adjuncts to symptom management rather than proven disease-modifying therapies.

27 Jan 2026

Scientists offer new insight into how common parasite T. gondii causes disease

A University of California, Riverside team of scientists has found that Toxoplasma gondii, a common parasite affecting up to one-third of the global population, is far more complex than previously believed.

27 Jan 2026

Study identifies genes, smoking, and obesity as pneumonia risk factors

Researchers at the University of Oulu have identified genes that increase susceptibility to pneumonia. Alongside inherited risk factors, smoking and higher body mass were also found to raise the risk of developing the disease.

27 Jan 2026

New atlas of brain lysosomes sheds light on neurodegenerative disorders

Functioning brain cells need a functioning system for picking up the trash and sorting the recycling. But when the cellular sanitation machines responsible for those tasks, called lysosomes, break down or get overwhelmed, it can increase the risk of Alzheimer's, Parkinson's, and other neurological disorders.

27 Jan 2026

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Genetic News and Research

Genetic inheritance and life experience leave distinct epigenetic marks in immune cells

Study reveals a link between oral microbiota and cognitive performance in schizophrenia

Genetic variants associated with rare inherited growth disorder identified in two prehistoric individuals

Study uncovers genes and proteins likely to play a causal role in Type 2 diabetes

Sharing thoughts and feelings may enhance recovery in stroke survivors

Umbilical cord blood markers may predict future type 1 diabetes

How DNA and life experiences leave distinct marks on the human immune system

Zebrafish can play a decisive role in clinical interpretation of spinal muscular atrophy

Redefining early detection for type 1 diabetes

New discovery may aid in early detection of rare genetic disease

Following the EAT-Lancet diet lowers chronic kidney disease risk

Research finds scientists view ELNs as “glorified filing cabinets,” driving frustration, duplication and shadow AI use

Study isolates mania-specific genetic architecture in bipolar disorder

First topical CRISPR gene therapy corrects disease-causing mutations in human skin

Antibody-producing plasma cells shape effectiveness of PD-1 immunotherapy

Tracking antibiotic resistance across environmental systems using advanced metagenomic tools

Gut problems may shape Parkinson’s disease progression through the gut-brain axis

Scientists offer new insight into how common parasite T. gondii causes disease

Study identifies genes, smoking, and obesity as pneumonia risk factors

New atlas of brain lysosomes sheds light on neurodegenerative disorders

Sequencing & Genomics: Elevating Science and Healthcare eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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