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First map of DNA modification in the hippocampus and prefrontal cortex created

A UCLA-led study has provided an unprecedented look at how gene regulation evolves during human brain development, showing how the 3D structure of chromatin - DNA and proteins - plays a critical role.

9 Oct 2024

Transposable elements found to be dysregulated in Alzheimer's brains, revealing potential targets for therapy

Study reveals widespread dysregulation of transposable elements (TEs) in aging human brains with Alzheimer's disease, using advanced techniques like CRISPR interference to identify TE-related risk genes.

9 Oct 2024

Study reveals why paternal mitochondria must be removed during early development

It's one of the basic tenets of biology: We get our DNA from our mom and our dad.

9 Oct 2024

Elevated blood glucose levels increase early-onset colorectal cancer risk

Study finds elevated blood glucose levels significantly increase the risk of colorectal cancer, with early-onset cases showing a stronger association. No non-linear relationships were detected.

8 Oct 2024

High-fiber diets transform gut microbiome, improving health across multiple diseases

Researchers identified two competing guilds of gut bacteria, one beneficial and one harmful, which can predict health outcomes and treatment success in diseases like type 2 diabetes.

8 Oct 2024

Relationship between intake of artificial sweeteners and adverse pregnancy outcomes

Researchers identify causal associations between artificial sweeteners and pregnancy outcomes.

8 Oct 2024

Overcoming CRISPR's side effects for therapeutic applications

CRISPR is a revolutionary tool that allows scientists to precisely modify the genome and gene expression of cells in any organism. It's a reagent - a substance that facilitates a reaction - that combines an enzyme with a programmable RNA capable of locating specific genetic sequences. Once guided to the correct spot, the enzyme acts like a pair of scissors, cutting, replacing, or deleting sequences of DNA.

7 Oct 2024

Single-cell genomics unveils secrets of the human microbiome

The human microbiome plays a critical role in our health, influencing everything from disease development to treatment responses.

7 Oct 2024

New deep-learning framework identifies non-addictive pain relief options

An estimated one in five Americans live with chronic pain and current treatment options leave much to be desired.

7 Oct 2024

Oropouche virus spreads in South America as scientists warn of potential outbreaks in the U.S.

Researchers review the reemergence and range expansion of Oropouche virus in South America, highlighting risks of spread to the U.S. and need for improved diagnostic tests. Over 9,000 cases and two deaths were reported in 2024.

4 Oct 2024

UK and Singapore partner on health data

Health Data Research UK (HDR UK) and the National Research Foundation Singapore (NRF) are pleased to have signed a Memorandum of Understanding (MoU) today, that formalizes a collaborative partnership in healthcare and data science.

3 Oct 2024

Scientists uncover two Crohn’s disease subtypes using lab-grown intestines, offering hope for personalized therapies

Researchers used stem-cell derived organoids from Crohn's disease patients to identify two molecular subtypes, paving the way for personalized treatments targeting specific disease characteristics.

2 Oct 2024

CheekAge can accurately predict the risk of mortality, study shows

We don't all age at the same rate. But while some supercentenarians may age exceptionally slowly due to winning the genetics jackpot, a plethora of behavioral and lifestyle factors are known to speed up aging, including stress, poor sleep, poor nutrition, smoking, and alcohol.

1 Oct 2024

Genome News and Research

First map of DNA modification in the hippocampus and prefrontal cortex created

Transposable elements found to be dysregulated in Alzheimer's brains, revealing potential targets for therapy

Study reveals why paternal mitochondria must be removed during early development

Elevated blood glucose levels increase early-onset colorectal cancer risk

High-fiber diets transform gut microbiome, improving health across multiple diseases

Relationship between intake of artificial sweeteners and adverse pregnancy outcomes

Overcoming CRISPR's side effects for therapeutic applications

Single-cell genomics unveils secrets of the human microbiome

New deep-learning framework identifies non-addictive pain relief options

Oropouche virus spreads in South America as scientists warn of potential outbreaks in the U.S.

UK and Singapore partner on health data

Scientists uncover two Crohn’s disease subtypes using lab-grown intestines, offering hope for personalized therapies

CheekAge can accurately predict the risk of mortality, study shows

Genetic study uncovers key drivers of metabolic syndrome with brain tissue links

Epigenetic hallmarks of cancer unveiled in new research

New insights improve genetic classification for hereditary colorectal cancer

Researchers advance ovarian cancer detection using cfDNA fragmentomes and protein biomarkers

Inflammatory proteins linked to higher risk of endometrial cancer

ERS Genomics and Université de Montréal sign CRISPR/Cas9 license agreement

Researchers uncover new disease-linked microbial species through pan-body microbiome analysis

The art of CRISPR: The power and promise of gene editing eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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