Physiology News and Research

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Human physiology is the science of the mechanical, physical, and biochemical functions of humans in good health, their organs, and the cells of which they are composed. The principal level of focus of physiology is at the level of organs and systems. Most aspects of human physiology are closely homologous to corresponding aspects of animal physiology, and animal experimentation has provided much of the foundation of physiological knowledge. Anatomy and physiology are closely related fields of study: anatomy, the study of form, and physiology, the study of function, are intrinsically tied and are studied in tandem as part of a medical curriculum.

Review: Phenotypes and origins of myeloid-derived suppressor cells

A new review was published in Oncotarget's Volume 13 on November 17, 2022, entitled, "Myeloid-derived suppressor cells: Cancer, autoimmune diseases, and more."

30 Nov 2022

Endogenous system may be responsible for delayed onset of diabetic retinopathy

About one third of patients with diabetes mellitus (DM) develop diabetic retinopathy (DR), a leading cause of blindness in working-age individuals. DR typically develops after many years of DM, and some patients do not develop DR for more than 50 years.

29 Nov 2022

UAB and Menkes International Association sign a donation agreement to boost research in Menkes disease

These funds, coming from the Menkes International Association, will allow a research project to search for new biomarkers to establish administration and monitoring protocols for a new drug that could improve the lives of children suffering from this rare disease.

29 Nov 2022

New microfluidic Organ Chip platform replicates the human vaginal tissue microenvironment

The human microbiome has been a hot topic over the last decade, with research pointing to disrupted bacterial communities as culprits for a host of maladies including irritable bowel syndrome, eczema, and autoimmune diseases.

28 Nov 2022

Simultaneous radiation and immunotherapy can benefit mNSCLC patients with high tumor aneuploidy

In many cancer types, cancer cells try to survive by escaping attack from the immune system. These cancer cells hijack mechanisms called immune checkpoints to trick the immune system into thinking they are healthy cells.

28 Nov 2022

Study provides first direct evidence of caffeine's ergogenicity on sprint running in athletics

At the international level of sport, even the smallest advantage can take an athlete from being a mere participant to a podium finisher.

28 Nov 2022

How micro(nano)plastics interact with human gut microbiota

In a recent study published in the Microbial Biotechnology journal, researchers explored the health effects of micro(nano)plastics and their degraded products on the gut microbiome.

27 Nov 2022

Astrocytes in the brains of epileptic mice exhibit an acid response with intensified seizures

Researchers at Tohoku University have shown that astrocytes in the mouse brain exhibit an acid response with intensified epileptic seizures.

25 Nov 2022

Study provides a key link between the social environment and healthy brains

As people age, maintaining a positive and predictable social environment becomes more and more important. For instance, keeping close ties with friends and family has been identified as one of the key ingredients to healthy aging.

24 Nov 2022

Repetitive stress induces features of accelerated aging in the eye

New research from the University of California, Irvine, suggests aging is an important component of retinal ganglion cell death in glaucoma, and that novel pathways can be targeted when designing new treatments for glaucoma patients.

21 Nov 2022

Gene mutation associated with autism causes an overstimulation of brain cells

Scientists looking to understand the fundamental brain mechanisms of autism spectrum disorder have found that a gene mutation known to be associated with the disorder causes an overstimulation of brain cells far greater than that seen in neuronal cells without the mutation.

21 Nov 2022

MIT researchers develop new technique for genome-wide studies of the liver

The liver’s ability to regenerate itself is legendary. Even if more than 70 percent of the organ is removed, the remaining tissue can regrow an entire new liver.

21 Nov 2022

UCF researcher examines the mechanisms of COVID-19 pathogenesis in patients with diabetes

Can a COVID-19 infection have long-term health effects on people with diabetes, including advancing their risk for heart disease?

20 Nov 2022

Dietary change could be a key to enhancing colon cancer treatment

A dietary change could be a key to enhancing colon cancer treatment, a new study from the University of Michigan Rogel Cancer Center finds.

20 Nov 2022

Gut microbiome in mice gets stressed within 24 hours on a high-fat diet

In a recent study published in the journal Cell Reports, researchers in Cincinnati, USA, assessed the impact of dietary alteration to a high-fat diet (HFD) on the intestine.

17 Nov 2022

Study reveals novel therapeutic targets for airway relaxation

Bronchial constriction is what makes many lung diseases like asthma so dangerous. Researchers have discovered a new signaling pathway that causes the airways to widen.

17 Nov 2022

Potential effects of nonoral versus oral gender-affirming estrogen therapy

A comprehensive review of research into the delivery method of estrogen treatment (e.g., oral, intramuscular injection, transdermal patch, etc.) and cardiovascular risk in transgender women and gender-diverse people found that treatment route may affect heart health, but there is not enough available data for metanalysis. The study is published ahead of print in the American Journal of Physiology-Heart and Circulatory Physiology. It was chosen as an APSselect article for November.

17 Nov 2022

Inhibitory neuron dysfunction emerges as a modulable mechanism of hyperexcitability

A small group of brain cells linked in a circuit is responsible for setting off whole-brain seizures in a rare form of epilepsy affected by blood sugar levels, a study led by UT Southwestern researchers suggests. The finding, published in Science Translational Medicine, could lead to new treatments for other metabolic disorders in the brain, the authors said.

17 Nov 2022

Diet containing excess salt can contribute to increased levels of stress, study shows

A diet containing lots of salt can contribute to increased levels of stress, a new study shows.

16 Nov 2022

Researchers identify potential lead compounds for the treatment of neuropsychiatric disorders

Currently, various classes of drugs are available for the treatment of mental illnesses - such as depression and anxiety disorders. However, although these drugs confer benefits, they are also associated with adverse side-effects.

15 Nov 2022

Physiology News and Research

Review: Phenotypes and origins of myeloid-derived suppressor cells

Endogenous system may be responsible for delayed onset of diabetic retinopathy

UAB and Menkes International Association sign a donation agreement to boost research in Menkes disease

New microfluidic Organ Chip platform replicates the human vaginal tissue microenvironment

Simultaneous radiation and immunotherapy can benefit mNSCLC patients with high tumor aneuploidy

Study provides first direct evidence of caffeine's ergogenicity on sprint running in athletics

How micro(nano)plastics interact with human gut microbiota

Astrocytes in the brains of epileptic mice exhibit an acid response with intensified seizures

Study provides a key link between the social environment and healthy brains

Repetitive stress induces features of accelerated aging in the eye

Gene mutation associated with autism causes an overstimulation of brain cells

MIT researchers develop new technique for genome-wide studies of the liver

UCF researcher examines the mechanisms of COVID-19 pathogenesis in patients with diabetes

Dietary change could be a key to enhancing colon cancer treatment

Gut microbiome in mice gets stressed within 24 hours on a high-fat diet

Study reveals novel therapeutic targets for airway relaxation

Potential effects of nonoral versus oral gender-affirming estrogen therapy

Inhibitory neuron dysfunction emerges as a modulable mechanism of hyperexcitability

Diet containing excess salt can contribute to increased levels of stress, study shows

Researchers identify potential lead compounds for the treatment of neuropsychiatric disorders

Industry Focus eBook - Cell biology (5th edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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