Macrophage News and Research

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A macrophage is a type of white blood cell that surrounds and kills microorganisms, removes dead cells, and stimulates the action of other immune system cells.

Researchers find macrophages to be crucial for tissue regeneration in mammals

A team of University of Kentucky researchers has discovered that macrophages, a type of immune cell that clears debris at injury sites during normal wound healing and helps produce scar tissue, are required for complex tissue regeneration in mammals.

16 May 2017

Study findings could pave way for better drugs to fight against parasitic infections

Immune cells, called macrophages, may rely on a compound to signal an attack to beat back attacks from parasitic worms, according to an international team of researchers, including Zissis C. Chroneos, associate professor of pediatrics, and microbiology and immunology at Penn State College of Medicine.

12 May 2017

Scientists reveal how immune cells activate to kill parasitic worms

An international team of researchers including Zissis C. Chroneos, associate professor of pediatrics, and microbiology and immunology at Penn State College of Medicine, reveals how immune cells called macrophages activate to kill parasitic worms.

11 May 2017

Scientists discover natural defense mechanism that kills TB bacteria

A natural mechanism by which our cells kill the bacterium responsible for tuberculosis (TB) has been discovered by scientists at the Francis Crick Institute, which could help in the battle against antibiotic-resistant bacteria.

11 May 2017

Research illuminates how primary colorectal tumors contribute to premetastatic 'niche' formation

Primary colorectal tumors secrete VEGF-A, inducing CXCL1 and CXCR2-positive myeloid-derived suppressor cell (MDSC) recruitment at distant sites and establishing niches for future metastases, report Medical University of South Carolina investigators in an article published online ahead of print on April 28, 2017 by Cancer Research.

10 May 2017

UAB symposium highlights use of tissue engineering to repair broken hearts

The third annual Cardiovascular Tissue Engineering Symposium met at the University of Alabama at Birmingham last month, a gathering of noted physicians and scientists who share the goal of creating new tissues and new knowledge that can prevent or repair heart disease and heart attacks.

9 May 2017

Study: Use of white blood cell boosting drugs found to be safe during chemo-radiotherapy of lung cancer

A late breaking subanalysis of the phase III CONVERT trial presented at the European Lung Cancer Conference shows that white blood cell boosting drugs are safe during concurrent chemo-radiotherapy of small cell lung cancer (SCLC).

5 May 2017

Phagocytosis educates the immune system

Phagocytosis is a biological mechanism whereby specialized cells ingest and degrade old, dead, or damaged cells to prevent tissue damage due to their accumulation.

4 May 2017

Mayo Clinic scientists develop novel nanoparticle to shrink tumors, prevent breast cancer recurrence

A Mayo Clinic research team has developed a new type of cancer-fighting nanoparticle aimed at shrinking breast cancer tumors, while also preventing recurrence of the disease.

2 May 2017

Research offers new way to improve nanopharmaceuticals for personalized medicine

In a newly published study in Nature Nanotechnology, the shape and geometry of nanoparticles can have a significant impact in modulating adverse injection reactions and offer realistic solutions for patients receiving nanopharmaceuticals—drug delivery systems specializing in microscopic-particle drug combinations.

27 Apr 2017

Scientists create new technique for studying how chlamydia interacts with immune system

Scientists at the Wellcome Trust Sanger Institute and their collaborators at the University of British Columbia have created an innovative technique for studying how chlamydia interacts with the human immune system.

25 Apr 2017

IRCM researchers discover how immunotherapy works in some cancer patients

What if our immune system could cure cancer? This logic seems almost too simple to be true, but it forms the basis of an emerging cancer treatment—immunotherapy.

19 Apr 2017

Air pollution may directly affect biology of upper airways to cause chronic sinus problems

Although human population studies have linked air pollution to chronic inflammation of nasal and sinus tissues, direct biological and molecular evidence for cause and effect has been scant.

18 Apr 2017

New study reveals sympathetic nervous system as main driver of thermogenesis

A new study from the Icahn School of Medicine at Mount Sinai provides important insights into how the body regulates its production of heat, a process known as thermogenesis that is currently intensely studied as a target of diabetes and obesity treatment in humans.

17 Apr 2017

Discovery of additional viral reservoir reveals new target for HIV cure research

HIV cure research to date has focused on clearing the virus from T cells, a type of white blood cell that is an essential part of the immune system.

17 Apr 2017

Study of interactions between chemokines pinpoints potential targets for treatment of inflammation

Signal molecules called chemokines often work in tandem to recruit specific sets of immune cells to sites of tissue damage.

7 Apr 2017

Researchers uncover critical pathway that helps pancreatic cancer cells turn off immune system

Researchers at NYU Langone Medical Center and its Perlmutter Cancer Center have uncovered a critical pathway by which pancreatic cancer cells turn off the immune system charged with attacking them. The findings appear in a paper published online in Nature Medicine April 10.

7 Apr 2017

Study explores how to predict and prevent psychiatric morbidity in survivors of ARDS

After surviving acute respiratory distress syndrome, a disease in which fluid begins to leak into the lungs of critically ill patients and makes it difficult to breathe, many patients develop mental illness.

5 Apr 2017

Researchers aim to examine therapeutic effect of iPS-ML producing interferon-β on liver cancer

All causes of the most common form of liver cancer, hepatocellular carcinoma, are not yet known, but the risk of getting it is increased by hepatitis B or C, cirrhosis, obesity, diabetes, a buildup of iron in the liver, or a family of toxins called aflatoxins produced by fungi on some types of food.

29 Mar 2017

LSTM scientists describe new approach to screening potential TB treatments

Scientists from LSTM's Research Centre for Drugs and Diagnostics (RCDD) have described in a paper published today in Scientific Reports, a new way of screening potential treatments for Tuberculosis (TB) which may assist in the identification and prioritisation of new therapies which could potentially reduce the duration of current TB treatment.

29 Mar 2017

Macrophage News and Research

Further Reading

Researchers find macrophages to be crucial for tissue regeneration in mammals

Study findings could pave way for better drugs to fight against parasitic infections

Scientists reveal how immune cells activate to kill parasitic worms

Scientists discover natural defense mechanism that kills TB bacteria

Research illuminates how primary colorectal tumors contribute to premetastatic 'niche' formation

UAB symposium highlights use of tissue engineering to repair broken hearts

Study: Use of white blood cell boosting drugs found to be safe during chemo-radiotherapy of lung cancer

Phagocytosis educates the immune system

Mayo Clinic scientists develop novel nanoparticle to shrink tumors, prevent breast cancer recurrence

Research offers new way to improve nanopharmaceuticals for personalized medicine

Scientists create new technique for studying how chlamydia interacts with immune system

IRCM researchers discover how immunotherapy works in some cancer patients

Air pollution may directly affect biology of upper airways to cause chronic sinus problems

New study reveals sympathetic nervous system as main driver of thermogenesis

Discovery of additional viral reservoir reveals new target for HIV cure research

Study of interactions between chemokines pinpoints potential targets for treatment of inflammation

Researchers uncover critical pathway that helps pancreatic cancer cells turn off immune system

Study explores how to predict and prevent psychiatric morbidity in survivors of ARDS

Researchers aim to examine therapeutic effect of iPS-ML producing interferon-β on liver cancer

LSTM scientists describe new approach to screening potential TB treatments

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