Organoids News and Research

RSS

Organoids are three-dimensional cell cultures from embryonic stem cells or induced pluripotent stem cells that model important features of whole organs.

Researchers use organoids to study the earliest moments of electrical activity in the brain

Humans have long wondered when and how we begin to form thoughts. Are we born with a pre-configured brain, or do thought patterns only begin to emerge in response to our sensory experiences of the world around us? Now, science is getting closer to answering the questions philosophers have pondered for centuries.

24 Nov 2025

Novel nanowire platform mimics brain tissue to study astrocytes

Scientists have engineered a nanowire platform that mimics brain tissue to study astrocytes, the star-shaped cells critical for brain health, for the first time in their natural state.

24 Nov 2025

Dexamethasone shows potential to fight therapy-resistant breast cancer metastases

The drug dexamethasone supplements cancer treatments to alleviate side effects of chemotherapy such as nausea or inflammation.

24 Nov 2025

Immune system abnormalities identified as core mechanism in major depressive disorder

Major depressive disorder (MDD) is characterized by a lowered mood and loss of interest, contributing not only to difficulties in academic and professional life but also as a major cause of suicide in South Korea.

21 Nov 2025

Novel therapy reduces tumor growth in models of triple-negative breast cancer

Researchers at the University of California San Diego School of Medicine have identified a promising new therapy for triple-negative breast cancer (TNBC), which is among the most aggressive and difficult-to-treat forms of the disease.

18 Nov 2025

New human-cell bone marrow model offers alternative to animal experiments

Our body's "blood factory" consists of specialized tissue made up of bone cells, blood vessels, nerves and other cell types.

18 Nov 2025

Innovative research reveals FGD3 as a key player in breast cancer cell death

A naturally occurring protein that tends to be expressed at higher levels in breast cancer cells boosts the effectiveness of some anticancer agents, including doxorubicin, one of the most widely used chemotherapies, and a preclinical drug known as ErSO, researchers report.

13 Nov 2025

Breakthrough in bone regeneration using nanoparticle-stem cell hybrid

A research team in South Korea has successfully developed a novel technology that combines nanoparticles with stem cells to significantly improve 3D bone tissue regeneration.

12 Nov 2025

Scientists turn human stomach cells into insulin-producing beta cells

Type 1 diabetes is caused by an insufficient production of the hormone insulin by cells in the pancreas called beta cells and estimated to affect 9.5 million people worldwide.

6 Nov 2025

New method brings hope for personalized treatment of inflammatory bowel disease

Patients with inflammatory bowel disease often have to wait a long time to find the right medicine. But the methods of a large interdisciplinary research team offer hope.

5 Nov 2025

Japanese study finds widespread reluctance to donate cells for brain organoid research

Research on human brain organoids (HBOs) is directly challenging how biobanks and biomedical institutes recruit volunteers.

4 Nov 2025

Stress hormones may silence crucial neuronal genes through specific RNA molecules

What if the brain's response to stress could be read not in fleeting neurotransmitter bursts, but in the quieting of genes deep inside chromatin? Researchers at the University of Alabama at Birmingham have now shown that stress hormones may silence crucial neuronal genes through an unexpected class of RNA molecules that operate not by encoding proteins, but by reshaping the genome's architecture.

4 Nov 2025

Study highlights bioengineered models as key to early cancer detection

Scientists are exploring leading-edge technologies that could transform how cancer is studied, detected and treated by catching it earlier, when it's more treatable and survival rates are highest.

3 Nov 2025

Pioneering technology enables scalable production of human kidney organoids

A research team led by the Institute for Bioengineering of Catalonia (IBEC) and collaborating with the Biomedical Research Institute of A Coruña (INIBIC), as well as other international research groups, has developed pioneering technology that enables human kidney organoids to be produced in a scalable manner.

31 Oct 2025

Lab-grown organoid offers a platform to study how liver scarring develops

As chronic liver disease becomes more widespread, researchers at Science Tokyo have developed a lab-grown organoid that replicates a regenerating liver, offering new hope for future treatments.

31 Oct 2025

Merck partners with Promega to advance 3-D cell dug discovery technologies

Merck, a leading science and technology company, has entered into a partnership with Promega Corporation, a global life science solutions and service leader based in Madison, Wisconsin in the US, to co-develop novel technologies that advance drug screening and discovery.

From Merck 30 Oct 2025