Small Cell Lung Cancer News and Research

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Small cell lung cancer is a disease in which malignant (cancer) cells form in the tissues of the lung. Small cell lung cancer is an aggressive (fast-growing) cancer that can spread to other parts of the body. The cancer cells look small and oval-shaped when looked at under a microscope.

Machine learning tool predicts cancer treatment response based on genetic mutations

A groundbreaking study led by USC Assistant Professor of Computer Science Ruishan Liu has uncovered how specific genetic mutations influence cancer treatment outcomes-insights that could help doctors tailor treatments more effectively.

11 Feb 2025

Ariceum Therapeutics receives FDA’s Orphan Drug Designation for targeted radionuclide cancer treatment

Ariceum Therapeutics (Ariceum), a private biotech company developing radiopharmaceutical products for the diagnosis and treatment of certain hard-to-treat cancers, today announced that the U.S. Food and Drug Administration (FDA) has granted Orphan Drug Designation (ODD) to 225Ac-SSO110 (satoreotide) for the treatment of patients with Small Cell Lung Cancer (SCLC).

10 Feb 2025

RUFY1-RET fusion identified as mechanism of resistance to lorlatinib in lung cancer

A new case report was published in Volume 16 of Oncotarget on February 5, 2025, titled "Acquired RUFY1-RET rearrangement as a mechanism of resistance to lorlatinib in a patient with CD74-ROS1 rearranged non-small cell lung cancer: A case report."

6 Feb 2025

Microbes in your gut could determine cancer treatment outcomes

Researchers reveal that gut microbiota influence the effectiveness of immune checkpoint inhibitors (ICIs) in cancer treatment, with specific bacterial strains enhancing or inhibiting anti-tumor immunity.

4 Feb 2025

Study could help predict treatment response for KRASG12C-mutant non-small cell lung cancer

A new study from Moffitt Cancer Center could help doctors predict how well patients with a specific type of lung cancer will respond to new therapies.

31 Jan 2025

Real-world data reveals survival benefits of anatomic resections for early-stage lung cancer

New research presented at the 2025 Society of Thoracic Surgeons (STS) Annual Meeting reveals that anatomic lung resections, such as lobectomy and segmentectomy, are associated with improved long-term survival compared to wedge resection for patients with early-stage non-small cell lung cancer (NSCLC).

26 Jan 2025

AstraZeneca receives positive NICE recommendations for lung cancer treatment

AstraZeneca announced that this week it has received two positive recommendations from the National Institute for Health and Care Excellence (NICE) for the treatment of lung cancer patients across England and Wales.

25 Jan 2025

Study finds anti-correlation of KLRG1 and PD-1 expression in tumor fighting T cells

A new research paper was published in Oncotarget's Volume 16 on January 20, 2025, titled "Anti-correlation of KLRG1 and PD-1 expression in human tumor CD8 T cells."

21 Jan 2025

Ultrasensitive ctDNA detection improves risk prediction in early-stage lung cancer

Ultrasensitive ctDNA detection with NeXT Personal shows 81% sensitivity in early-stage lung adenocarcinoma, improving prognostic accuracy and therapy guidance.

15 Jan 2025

NCCN global meeting focuses on cancer care in the MENA region

The National Comprehensive Cancer Network (NCCN)-a global not-for-profit alliance of leading cancer centers-is taking part in a two-day meeting at the Middle East North Africa (MENA)-NCCN Regional Coordinating Center, beginning today.

11 Jan 2025

Medicare Advantage leads to lower cancer drug costs in colorectal cancer

A new study examining the use of high-cost drugs among patients with colorectal cancer and non-small cell lung cancer found those insured through Medicare Advantage received less expensive cancer drugs compared to others on Traditional Medicare.

10 Jan 2025

Machine learning reveals why cancer trials fall short in real-world patients

TrialTranslator uses machine learning to assess cancer RCT generalizability, revealing survival gaps for high-risk patients and enhancing research accuracy.

10 Jan 2025

RNA nanoparticles offer dual action against prostate tumors

Yang Zhang, PhD, and Jinjun Shi, PhD, both of the Center for Nanomedicine and Department of Anesthesiology, Perioperative and Pain Medicine at Brigham and Women's Hospital, are co-senior authors of a paper published in ACS Nanoscience Au, "Lipid Nanoparticle Delivery of mRNA and siRNA for Concurrent Restoration of Tumor Suppressor and Inhibition of Tumorigenic Driver in Prostate Cancer."

10 Jan 2025

Mussel-inspired nanoparticles for targeted lung cancer therapy

Researchers from POSTECH and Kyungpook National University have developed a novel inhalable therapeutic delivery system for lung cancer, leveraging mucoadhesive protein nanoparticles inspired by the adhesive properties of marine mussels.

9 Jan 2025

Stanford researchers develop AI model to enhance cancer prognosis predictions

The melding of visual information (microscopic and X-ray images, CT and MRI scans, for example) with text (exam notes, communications between physicians of varying specialties) is a key component of cancer care.

8 Jan 2025

New AI system aims to improve real-world application of clinical trial results

A new study led by Winship Cancer Institute of Emory University and Abramson Cancer Center of University of Pennsylvania researchers demonstrates that a first-of-its-kind platform using artificial intelligence (AI) could help clinicians and patients assess whether and how much an individual patient may benefit from a particular therapy being tested in a clinical trial.

8 Jan 2025

Small Cell Lung Cancer News and Research

Machine learning tool predicts cancer treatment response based on genetic mutations

Ariceum Therapeutics receives FDA’s Orphan Drug Designation for targeted radionuclide cancer treatment

RUFY1-RET fusion identified as mechanism of resistance to lorlatinib in lung cancer

Microbes in your gut could determine cancer treatment outcomes

Study could help predict treatment response for KRASG12C-mutant non-small cell lung cancer

Real-world data reveals survival benefits of anatomic resections for early-stage lung cancer

AstraZeneca receives positive NICE recommendations for lung cancer treatment

Study finds anti-correlation of KLRG1 and PD-1 expression in tumor fighting T cells

Ultrasensitive ctDNA detection improves risk prediction in early-stage lung cancer

NCCN global meeting focuses on cancer care in the MENA region

Medicare Advantage leads to lower cancer drug costs in colorectal cancer

Machine learning reveals why cancer trials fall short in real-world patients

RNA nanoparticles offer dual action against prostate tumors

Mussel-inspired nanoparticles for targeted lung cancer therapy

Stanford researchers develop AI model to enhance cancer prognosis predictions

New AI system aims to improve real-world application of clinical trial results

New molecular imaging agent can accurately identify crucial cancer biomarker

Chemical compound lights up treatment-resistant cancers on imaging scans

Multi-omic profiling sheds light on chemo-immunotherapy resistance in lung cancer

PROSPECT-Lung trial aims to improve treatment for patients with resectable non-small cell lung cancer

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