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Human gut microbiome: A source of new antibiotic peptides

Researchers identified 323 peptide-based antimicrobials from the human microbiome, with 71% showing significant antibacterial activity, and the lead peptide, prevotellin-2, matching the efficacy of polymyxin B in both in vitro and in vivo models.

25 Aug 2024

Wake Forest Institute for Regenerative Medicine joins new NSF-funded pandemic prediction initiative

The Wake Forest Institute for Regenerative Medicine is proud to be part of a new initiative, supported by an $18 million grant from the U.S. National Science Foundation (NSF), aimed at enhancing global pandemic prediction and prevention capabilities.

23 Aug 2024

Investigating the benefits of refined bamboo vinegar in anti-acne cosmetic formulations

Bamboo vinegar is a concentrated liquid obtained from bamboo under high temperature and anaerobic conditions.

23 Aug 2024

Protein from gut worms accelerates skin regeneration and reduces scarring

Researchers at Rutgers University in New Jersey have discovered that a protein produced by parasitic worms in the gut enhances wound healing in mice.

23 Aug 2024

Understanding the mechanisms post-surgery pain

An international research group led by MedUni Vienna and IMBA - Institute of Molecular Biotechnology, Vienna, has made significant progress in understanding the mechanisms that influence the sensation of pain after surgery.

23 Aug 2024

IU researchers secure $4 million for veterans' health research

Indiana University School of Medicine researchers have cumulatively been awarded nearly $4 million in grant funding through the U.S. Department of Veterans Affairs' Merit Review Award and Career Development programs to support research on diabetes, skin inflammation, cancer and aging.

23 Aug 2024

Defective ZNRF3 gene causes opposing brain sizes and potential tumor risk

A gene called ZNRF3, known to be involved in cancer, also messes with the mind. The human brain relies on two copies of this gene to build a right-sized brain. If one of the copies is defective, the brain will be either too small or too large - known as mirror effect -, leading to various neurological symptoms.

23 Aug 2024

Risankizumab outperforms ustekinumab in treating moderate-to-severe Crohn’s disease

Researchers compare the therapeutic efficacy of risakizumab and ustekinumab for the treatment of moderate-to-severe Crohn’s disease.

23 Aug 2024

New Mpox strain sparks global health alert

On Wednesday, August 14th, 2024, in response to the active circulation of clade 1 monkeypox virus (MPXV) in Central Africa and the recent expansion of a subtype (1b) thought to be more lethal and transmissible in East Africa, the World Health Organization (WHO) declared a public health emergency of international concern (PHEIC), paving the way for enhanced coordination between regional health systems and the active engagement of stakeholders to tackle this global outbreak. The following day, Thursday August 15, Sweden reported the first positive case of clade 1b mpox on European soil. This led the French government to place the French health system on maximum alert on Friday, August 16, and the French authorities have now begun to re-evaluate the health recommendations established in 2022 during the previous mpox outbreak in preparation for the probable emergence of cases in the country.

23 Aug 2024

The impact of stem cells on the epigenetic clock

How old are you, really? Your chronological age is the number of years you have been alive. Your biological age is how old your cells are which scientists believe may better assess one's age-related health and disease risk. People biologically age at different rates, depending on genetic and environmental factors, so that a person's chronological age does not necessarily match their biological age. In recent years, direct-to-consumer biological age tests have become increasingly accessible and popular as interest has increased in this nascent science.

23 Aug 2024

Mosquitoes detect infrared radiation for host seeking

While a mosquito bite is often no more than a temporary bother, in many parts of the world it can be scary. One mosquito species, Aedes aegypti, spreads the viruses that cause over 100,000,000 cases of dengue, yellow fever, Zika, and other diseases every year. Another, Anopheles gambiae, spreads the parasite that causes malaria. The World Health Organization estimates that malaria alone causes more than 400,000 deaths every year. Indeed, their capacity to transmit disease has earned mosquitoes the title of deadliest animal.

23 Aug 2024

Study shows frequent mitochondrial DNA insertion in the brain cells

As direct descendants of ancient bacteria, mitochondria have always been a little alien.

22 Aug 2024

Maintaining healthy weight could lower risk of immune-mediated skin diseases in kids

Childhood obesity can contribute to the development of common immune-mediated skin diseases (IMSDs), such as alopecia areata, atopic dermatitis, and psoriasis, new research finds.

21 Aug 2024

New index identifies school-age children likely to have long COVID

A research team led by the National Institutes of Health's RECOVER Initiative and supported by its Clinical Science Core (CSC) at NYU Langone Health, has designed a new way to identify which school-age children and adolescents most likely have Long COVID.

21 Aug 2024

Hair follicles use unique sensor system to clean up dead cells

Billions of our cells die every day to make way for the growth of new ones. Most of these goners are cleaned up by phagocytes - mobile immune cells that migrate where needed to engulf problematic substances.

21 Aug 2024

Spatial transcriptomics unlocks malaria's liver stage secrets

For the malaria parasite to reach the blood of its human host, it must first enter the liver, where only a small number of parasites differentiate and replicate for upwards of seven days, making it a bottleneck in the parasite's lifecycle. This bottleneck makes the liver stage an optimal target for effective and long-lasting vaccines against the disease. Using Spatial Transcriptomics and single-cell RNA-sequencing technologies, researchers at Stockholm University have for the first time managed to create a spatio-temporal map of malaria infection in the mouse liver. A study that was recently published in Nature Communications.

21 Aug 2024

Engineered heart tissues uncover new mechanisms in lupus-related heart damage

Cardiovascular disease is the leading cause of death in patients suffering from lupus, an autoimmune disease in which our immune system attacks our own tissues and organs, the heart, blood, lung, joints, brain, and skin.

20 Aug 2024

UofL researchers receive $3.6 million to study the role of arsenic exposure in causing health problems

University of Louisville researchers have received $3.6 million in new grant funding to study the role of arsenic exposure in causing cancer and other major health concerns.

20 Aug 2024

UC Davis Health experts urge wildfire preparedness action plans to support patients with respiratory diseases

A multidisciplinary team of UC Davis Health experts are calling on health systems to create wildfire preparedness action plans to support patients with preexisting respiratory diseases.

19 Aug 2024

Researchers identify possible candidates for multipotent stem cells in the sea anemone

The sea anemone Nematostella vectensis is potentially immortal. Using molecular genetic methods, developmental biologists led by Ulrich Technau from the University of Vienna have now identified possible candidates for multipotent stem cells in the sea anemone for the first time.

19 Aug 2024