Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

Rigaku Acquires Life Science Imaging Equipment Manufacturer MILabs

Rigaku Corporation (Headquarters: Akishima-shi, Tokyo; President: Toshiyuki Ikeda; "Rigaku"), a leading manufacturer of X-ray analysis equipment, has acquired all issued shares of MILabs B.V. (Headquarters: Houten, The Netherlands; CEO and CSO: Dr. Frederik Beekman; “MILabs”)

From Rigaku Corporation 4 Aug 2021

Next-Generation Sequencing and the Diagnosis of Disease

In this interview, Professor John Rossen talks about next-generation sequencing and it's implications for the diagnosis of disease.

From Tecan 4 Aug 2021

Discovery may enable the development of new therapies to kill aggressive cancer cells

Vanderbilt faculty and researchers are looking for the "Achilles' heel" of the cancer cells that survive initial chemotherapy.

3 Aug 2021

NSF awards $441,028 to address the workforce needs of regenerative medicine

Regenerative medicine is a cross-disciplinary field that aims to repair or replace abnormal organs by growing tissues in the laboratory or cells for therapy.

3 Aug 2021

What is the potential of microphysiological systems in COVID-19 research?

In a recently published review article in the journal Drug Discovery Today, scientists have described the utility of human-based microphysiological systems MPSs in understanding the pathophysiology of SARS-CoV-2 infection and developing effective therapeutic interventions. Moreover, they have described the establishment of a global working group to synchronize recent developments around MPSs and COVID-19 research.

3 Aug 2021

Latin American and Caribbean research contributions to tackle challenges posed by brain diseases

Every year there are nearly ten million new cases of dementia globally, of which Alzheimer's Disease (AD) is the most common form, accounting for around 60-70% of cases.

2 Aug 2021

Next generation automation lab achieves huge productivity gains

Eli Lilly and Company and their industry partners, including sample management specialists – Ziath, are speeding the discovery of new medicines through the fully automated Lilly Life Sciences Studio lab in San Diego, USA.

From Ziath Ltd 30 Jul 2021

Study could lead to blood-based diagnostic test for schizophrenia

Scientists at Sanford Burnham Prebys have discovered how levels of a protein could be used in the future as a blood-based diagnostic aid for schizophrenia.

27 Jul 2021

Metrion Biosciences appoints Nick Foster as Chief Commercial Officer and Head of Global Business Development

Metrion today announced the appointment of Nick Foster as Chief Commercial Officer and Head of Global Business Development.

26 Jul 2021

Researchers identify an unexpected effect for already characterized active substances

Every innovative drug starts with the search for an active substance targeting key players in disease-related processes.

23 Jul 2021

ATN framework can be extended to detect frontotemporal degeneration

Alzheimer's disease and related diseases can still only be confirmed in deceased patients' brains via autopsy.

20 Jul 2021

Researchers use appendiceal cancer organoids to study personalized immunotherapy response

Wake Forest researchers and clinicians are using patient-specific tumor 'organoid' models as a preclinical companion platform to better evaluate immunotherapy treatment for appendiceal cancer, one of the rarest cancers affecting only 1 in 100,000 people.

19 Jul 2021

New live cell models lay the groundwork for studies into mitochondrial diseases

The mitochondrion has garnered quite the reputation for its role as the "powerhouse of the cell." These tiny, but mighty organelles play various life-sustaining roles, from powering our own cells and organs to fueling chemical and biological processes.

15 Jul 2021

UH researchers report new gut–liver drug recycling process

A team of University of Houston pharmaceutical researchers is reporting a newly recognized process of drug metabolism in the intestines - followed by recycling through the liver - that could have important implications for developing treatments for intestinal diseases and for taking multiple medications at the same time.

14 Jul 2021

Curia to Acquire US-based LakePharma, Expanding End-to-End R&D Capabilities and Scale for Biologics

Curia today announced it has entered into a definitive agreement to acquire LakePharma Inc.

From Curia 14 Jul 2021

New approach that uses machine learning could transform drug development

Writing in the July 12, 2021 online issue of Nature Communications, researchers at University of California San Diego School of Medicine describe a new approach that uses machine learning to hunt for disease targets and then predicts whether a drug is likely to receive FDA approval.

12 Jul 2021

Untargeted metabolomics profiling can improve diagnosis of metabolic disorders in newborns

A team led by researchers at Baylor College of Medicine found that a screening method known as untargeted metabolomics profiling can improve the diagnostic rate for inborn errors of metabolism, a group of rare genetic conditions, by about seven-fold when compared to the traditional metabolic screening approach.

12 Jul 2021

Repurposed drugs for COVID-19 treatment identified through virtual screening and cell-based assays

A joint research group from KAIST and Institut Pasteur Korea has identified repurposed drugs for COVID-19 treatment through virtual screening and cell-based assays.

8 Jul 2021

Novel technique allows to individually select droplets for contact in droplet-array sandwiching

Miniaturization is rapidly reshaping the field of biochemistry, with emerging technologies such as microfluidics and "lab-on-a-chip" devices taking the world by storm. Chemical reactions that were normally conducted in flasks and tubes can now be carried out within tiny water droplets not larger than a few millionths of a liter.

8 Jul 2021

Using AI to find new pharmaceutical applications for natural products

Artificial intelligence (AI) is able to recognize the biological activity of natural products in a targeted manner, as researchers at ETH Zurich have demonstrated.

7 Jul 2021

Drug Discovery News and Research

Further Reading

Rigaku Acquires Life Science Imaging Equipment Manufacturer MILabs

Next-Generation Sequencing and the Diagnosis of Disease

Discovery may enable the development of new therapies to kill aggressive cancer cells

NSF awards $441,028 to address the workforce needs of regenerative medicine

What is the potential of microphysiological systems in COVID-19 research?

Latin American and Caribbean research contributions to tackle challenges posed by brain diseases

Next generation automation lab achieves huge productivity gains

Study could lead to blood-based diagnostic test for schizophrenia

Metrion Biosciences appoints Nick Foster as Chief Commercial Officer and Head of Global Business Development

Researchers identify an unexpected effect for already characterized active substances

ATN framework can be extended to detect frontotemporal degeneration

Researchers use appendiceal cancer organoids to study personalized immunotherapy response

New live cell models lay the groundwork for studies into mitochondrial diseases

UH researchers report new gut–liver drug recycling process

Curia to Acquire US-based LakePharma, Expanding End-to-End R&D Capabilities and Scale for Biologics

New approach that uses machine learning could transform drug development

Untargeted metabolomics profiling can improve diagnosis of metabolic disorders in newborns

Repurposed drugs for COVID-19 treatment identified through virtual screening and cell-based assays

Novel technique allows to individually select droplets for contact in droplet-array sandwiching

Using AI to find new pharmaceutical applications for natural products

eBook: Mastering plate reader assays for drug discovery eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo