Immune System News and Research

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New lab method accelerates diagnosis of genetic disorders of the immune system

A new laboratory method developed by researchers at Columbia University Vagelos College of Physicians and Surgeons may now help physicians more quickly diagnose patients with suspected genetic disorders of the immune system, many who have been trapped in diagnostic limbo for years.

20 Jun 2025

Cord blood proteins help detect early sepsis in preterm infants

Scientists from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago and colleagues identified several proteins from the umbilical cord blood of preterm newborns that signal acute systemic inflammation as an immune response to infection, providing objective and noninvasive means to diagnose early onset sepsis.

20 Jun 2025

Immune changes predict heart risks in cancer patients on checkpoint inhibitors

New research has uncovered immune changes in cancer patients that could help identify which patients are most at risk of dangerous heart complications from cancer drugs, known as immune checkpoint inhibitors.

20 Jun 2025

AI reveals how H5N1 virus is evolving to evade human immunity

The H5N1 avian influenza virus has infected birds and mammals around the world. As of June 2025, 70 people have been infected, and 1 person has died in the United States.

20 Jun 2025

Inflammation and immune dysregulation drive breast cancer in aging women

Age-related and postmenopausal breast cancer progression remains a significant challenge, with growing evidence pointing to the role of pro-inflammatory cytokines and CXC chemokines in tumor development and immune system modulation.

20 Jun 2025

Autoantibodies against vinculin linked to childhood kidney disease

Idiopathic nephrotic syndrome (INS) is a serious kidney disease in children with no clear cause. In a recent study, researchers have identified a novel autoantibody targeting vinculin—a protein crucial for kidney cell structure—as a significant factor in INS.

19 Jun 2025

Weight loss surgery leads to significant boost in self esteem

Self-esteem scores more than doubled within one year of weight-loss surgery, according to a new study* presented today at the American Society for Metabolic and Bariatric Surgery (ASMBS) 2025 Annual Scientific Meeting.

19 Jun 2025

Chemical pairing of BPA and retinoic acid disrupts brain development

Synthetic chemicals and plastics are useful and indispensable in our lives. On the other hand, the world is grappling with plastic pollution-clogging oceans, threatening wildlife, and leaching into ecosystems.

19 Jun 2025

Rapamycin offers life-extending benefits comparable to eating less

The anti-aging drug Rapamycin has the same life-extending effect as eating less, according to new research from the University of East Anglia and University of Glasgow.

19 Jun 2025

Research reveals how a microscopic parasite disrupts brain function

A team of scientists at the University of California, Riverside, explains in a paper published in PLOS Pathogens how a microscopic parasite, Toxoplasma gondii, can significantly disrupt brain function, even when it infects only a small number of neurons.

19 Jun 2025

T cells play key role in early stages of Parkinson’s disease

Your T cells work hard to fight disease. Unfortunately, "friendly fire" from T cells can sometimes harm the body's healthy tissues.

19 Jun 2025

C-Path’s TRxA awards $250,000 grant to develop novel treatment for type 1 diabetes

Critical Path Institute's (C-Path) Translational Therapeutics Accelerator (TRxA) proudly announced today a $250,000 grant award aimed at developing a novel treatment for type 1 diabetes (T1D).

19 Jun 2025

New dual-adjuvant vaccine strategy offers hope in the fight against HIV

In the quest to develop an effective HIV vaccine, scientists from Scripps Research have made a significant leap forward. They found that a two-part delivery strategy can train the immune system to produce a stronger response to HIV, offering new hope in the fight against one of the world's most elusive viruses.

19 Jun 2025

Kupffer cell reprogramming in embryos explains metabolic disorders in offspring

Children born to obese mothers are at higher risk of developing metabolic disorders, even if they follow a healthy diet themselves.

18 Jun 2025

Inhibiting RNA Polymerase 1 suppresses tumor growth in hard-to-treat cancers

Researchers at the Johns Hopkins Kimmel Cancer Center and Department of Radiation Oncology and Molecular Radiation Sciences uncovered a new tumor-suppressive response that could lead to novel therapies targeting hard-to-treat cancers.

18 Jun 2025

Stanford study identifies gene signature that predicts immune health

At the start of the COVID-19 pandemic, information began to trickle in about who was at higher risk of a dangerous outcome from infection. Men. Those over 65. Smokers. Those with obesity.

18 Jun 2025

CAR T-cell therapy successfully treats rare autoimmune disease of the peripheral nervous system

Physicians from Bochum have used a cancer treatment method to treat severe autoimmune diseases.

18 Jun 2025

Interferon pathway genes linked to treatment success in juvenile arthritis

A set of genes that could be used to help doctors predict which children will respond well to treatment for juvenile idiopathic arthritis (JIA) have been identified by researchers at UCL and Great Ormond Street Hospital for Children (GOSH), who are part of the CLUSTER Consortium.

18 Jun 2025

Compound-level diet analysis sheds light on hidden triggers in IBD

Dutch researchers identified specific food compounds that influence remission and flare risk in patients with inflammatory bowel disease. The study shows compound-level dietary analysis could help personalize IBD management and clarify conflicting advice about diet.

18 Jun 2025

OCCAM Immune and Cancer Research Institute join forces to advance immunotherapy

In a new collaboration that could transform how cancer is treated, OCCAM Immune-a Mount Sinai initiative focused on understanding the immune system's role in disease-is partnering with the Cancer Research Institute (CRI) to unlock the secrets of how the immune system responds to advanced therapies.

17 Jun 2025