Therapy News and Research

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Diet high in refined carbohydrates may trigger insomnia

An estimated 30% of adults experience insomnia, and a new study by researchers at Columbia University Vagelos College of Physicians and Surgeons suggests that diet may be partly to blame.

11 Dec 2019

University Of Iowa wins $18 million grant to continue study on Huntington's disease

Peg Nopoulos, MD, chair of psychiatry and professor of psychiatry, neurology, and pediatrics in the University of Iowa Carver College of Medicine, has received a five-year, $18 million grant from the National Institute of Neurological Disorders and Stroke to continue and expand a decade-long study on brain development in children at risk for developing Huntington's Disease.

11 Dec 2019

Yale scientists flip the script on novel cancer therapy to find new insights into lupus

In the last decade, scientists discovered that blocking a key regulator of the immune system helped unleash the body's natural defenses against several forms of cancer, opening up a new era of cancer immunotherapy.

11 Dec 2019

Immune cells repair damaged gut in children with IBD

According to a new study published in the journal Gastroenterology, immune cells of a certain kind which regulate inflammatory processes and even help restore normal gut function after inflammation could be of great use to treat children with inflammatory bowel disease (IBD).

11 Dec 2019

Epigenome editing could repair genetic brain disorder

A new study published in the journal Nature Communications shows that it may be possible to reverse gene mutations that cause brain disorders, using a very precisely targeted epigenome editing technique. This type of gene editing does not change the gene’s DNA sequence itself but is focused on correcting epigenome changes only. The condition that was corrected in the study is called the WAGR syndrome and is associated with obesity and intellectual disability in people.

11 Dec 2019

Health risks associated with NSAIDs as a factor for increased opioid prescribing

Patients with chronic pain caught between cardiovascular concerns about non-opioid analgesics and addiction risks of opioids, likely causing significant unmet need for pain relief.

11 Dec 2019

New drug combo promises help for triple negative breast cancer patients

A new preclinical study on triple negative breast cancer (TNBC) reports that an experimental polo-like kinase 1 (PLK1) inhibitor shrank tumor four times more powerfully when used along with standard drugs than alone. The study, reported in the journal PLOS ONE, opens up a new door of opportunity for patients with this disease.

11 Dec 2019

Help for teenagers who want to quit smoking

A new study published in the journal JAMA Pediatricsreports on the use of varenicline, a drug that helps smokers quit. The study is unique in that it targeted teenagers who wanted to quit. While confirming the low overall efficacy of the drug, it shows that it may perhaps help teenage smokers to quit faster and to stay smoke-free longer.

11 Dec 2019

Non-drug therapies may reduce adverse outcomes in service members with chronic pain

A new study based on Veterans Affairs health records finds that non-drug therapies given to military service members with chronic pain may reduce the risk of long-term adverse outcomes, such as alcohol and drug disorder and self-induced injuries, including suicide attempts.

11 Dec 2019

New system enables real-time observations of individual cells in the colon

Biomedical engineers at Duke University have developed a system that allows for real-time observations of individual cells in the colon of a living mouse.

11 Dec 2019

Efforts to prevent new HIV transmissions must also focus on people already living with HIV

Efforts to prevent new HIV transmissions in the United States must be accompanied by advances in addressing HIV-associated comorbidities to improve the health of people already living with HIV, National Institutes of Health experts assert in the third of a series of JAMA commentaries.

11 Dec 2019

Researchers develop 'scar in a dish' model to closely mimic progressive organ scarring

Every organ in the body is capable, to some extent, of repairing itself after an injury. As part of this process, scar tissue forms and then recedes to make room for normal tissue when healing is complete.

11 Dec 2019

New therapy shows dramatic effect against worst types of leukaemias

A collaborative research effort by Australian and US scientists has led to the discovery of a promising new approach to treating some of the worst types of leukaemia, including an aggressive leukaemia that mostly affects babies.

11 Dec 2019

Jefferson hotspotting program uses team-based model to addresses hospital 'super utilizers'

The United States faces a crisis in providing complex care for high-need, high-cost individuals--people who often suffer economic, mental and physical challenges.

11 Dec 2019

Treatment combination improves survival in advanced HER2-positive breast cancer patients

Researchers from The University of Texas MD Anderson Cancer Center today reported study results showing the addition of tucatinib to capecitabine (Xeloda) and trastuzumab (Herceptin) significantly improved progression-free survival (PFS) and overall survival (OS) in patients with advanced HER2-positive breast cancer, with and without brain metastasis according to results of the HER2CLIMB clinical trial.

11 Dec 2019

Research suggests new strategies for developing psoriasis therapies

Psoriasis is a skin disorder that affects at least 100 million individuals worldwide. Its economic impact is more than $10 billion annually in the U.S. alone.

11 Dec 2019

Low-dose aspirin not associated with reduced risk of heart attack among African Americans

Low-dose aspirin was not associated with a reduced risk of a fatal heart attack among African Americans, according to an observational study published in the Journal of the American Heart Association, the open access journal of the American Heart Association.

11 Dec 2019

Researchers create 'lab on a chip' devices to help medics monitor patients’ health in real-time

Researchers have identified a way of allowing medics to use tiny laboratories to monitor their patients’ health in real-time and deliver a greater level of personal care than ever before.

11 Dec 2019

Genetic variant mainly found in individuals of African ancestry increases odds of heart failure

A genetic variant in the gene transthyretin (TTR)- which is found in about 3 percent of individuals of African ancestry- is a more significant cause of heart failure than previously believed, according to a multi-institution study led by researchers at Penn Medicine.

10 Dec 2019

Study may help explain why deep-brain stimulation does not work for everyone

People with severe Parkinson's disease or other neurological conditions that cause intractable symptoms such as uncontrollable shaking, muscle spasms, seizures, obsessive thoughts and compulsive behaviors are sometimes treated with electric stimulators placed inside the brain.

10 Dec 2019

Therapy News and Research

Diet high in refined carbohydrates may trigger insomnia

University Of Iowa wins $18 million grant to continue study on Huntington's disease

Yale scientists flip the script on novel cancer therapy to find new insights into lupus

Immune cells repair damaged gut in children with IBD

Epigenome editing could repair genetic brain disorder

Health risks associated with NSAIDs as a factor for increased opioid prescribing

New drug combo promises help for triple negative breast cancer patients

Help for teenagers who want to quit smoking

Non-drug therapies may reduce adverse outcomes in service members with chronic pain

New system enables real-time observations of individual cells in the colon

Efforts to prevent new HIV transmissions must also focus on people already living with HIV

Researchers develop 'scar in a dish' model to closely mimic progressive organ scarring

New therapy shows dramatic effect against worst types of leukaemias

Jefferson hotspotting program uses team-based model to addresses hospital 'super utilizers'

Treatment combination improves survival in advanced HER2-positive breast cancer patients

Research suggests new strategies for developing psoriasis therapies

Low-dose aspirin not associated with reduced risk of heart attack among African Americans

Researchers create 'lab on a chip' devices to help medics monitor patients’ health in real-time

Genetic variant mainly found in individuals of African ancestry increases odds of heart failure

Study may help explain why deep-brain stimulation does not work for everyone

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