Oncology News and Research

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Oncology, meaning bulk, mass, or tumor, and the suffix ''-logy'', meaning "study of") is a branch of medicine that deals with tumors (cancer). A medical professional who practices oncology is an ''oncologist''.

Targeting CD47 protein could improve colorectal cancer treatment

A new study from the USC Norris Comprehensive Cancer Center has found evidence that targeting CD47, a protein that is part of the innate immune system, could be a key step in fighting colorectal cancer.

7 Nov 2024

UAB team develops a combined score to predict cancer treatment success

In 1937, President Franklin Roosevelt signed the National Cancer Act, launching a nationwide effort to combat the disease.

7 Nov 2024

Study highlights long-term risks of prostate cancer treatment

The risks of adverse effects and complications from treatment for prostate cancer are substantial and continue for years after treatment ends.

7 Nov 2024

New NCCN guidelines include expanded genetic risk assessment for various cancers

The National Comprehensive Cancer Network (NCCN) - an alliance of leading cancer centers focusing on maintaining evidence-based expert consensus driven guidelines for care - announces the publication of the expanded NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Genetic/Familial High-Risk Assessment: Breast, Ovarian, Pancreatic, and Prostate.

7 Nov 2024

New SCLC biomarkers enable advances in precision medicine approaches

A new research paper was published in Oncotarget's Volume 15 on October 11, 2024, entitled "Relationship between the expressions of DLL3, ASC1, TTF-1 and Ki-67: First steps of precision medicine at SCLC"

6 Nov 2024

Stanford researchers unveil the key role of extrachromosomal DNA in cancer

A trio of research papers from Stanford Medicine researchers and their international collaborators transforms scientists' understanding of how small DNA circles - until recently dismissed as inconsequential - are major drivers of many types of human cancers.

6 Nov 2024

Researchers uncover immune mechanism behind myocarditis from cancer immunotherapy

Some patients being treated with immune checkpoint inhibitors, a type of cancer immunotherapy, develop a dangerous form of heart inflammation called myocarditis.

6 Nov 2024

New insights into the role of innate immunity in tumor initiation

Along with defending against pathogens, the body's innate immune system helps to protect the stability of our genomes in unexpected ways - ways that have important implications for the development of cancer, researchers at Memorial Sloan Kettering Cancer Center (MSK) are discovering.

5 Nov 2024

New research uncovers 16 genes that aid breast cancer survival

Scientists at the Johns Hopkins Kimmel Cancer Center have identified 16 genes that breast cancer cells use to survive in the bloodstream after they've escaped the low-oxygen regions of a tumor.

5 Nov 2024

$2.5 million grant supports lung cancer screening for marginalized communities

A multidisciplinary team of experts in lung cancer screening and implementation science from the UCLA Health Jonsson Comprehensive Cancer Center, the David Geffen School of Medicine at UCLA and the UCLA Fielding School of Public Health was awarded a $2.5 million grant from the Bristol Myers Squibb Foundation, an independent charitable organization, to spearhead a new initiative aimed at reducing disparities in lung cancer screening across Los Angeles County.

4 Nov 2024

Unexpected immunotherapy success in rare pancreatic cancer

A new case report was published in Oncotarget's Volume 15 on October 11, 2024, entitled "A case of adenosquamous pancreatic cancer with a KRAS G12C mutation with an exceptional response to immunotherapy"

4 Nov 2024

NCCN leaders collaborate to enhance cancer care in Vietnam

As part of ongoing work to define and advance high-quality cancer care globally, leaders from the National Comprehensive Cancer Network (NCCN) - an alliance of leading cancer centers in the United States - will be in Vietnam today to collaborate on improving cancer care standards throughout the country.

1 Nov 2024

Quitting smoking after cancer diagnosis can add years to patient lives

Quitting smoking within six months after a cancer diagnosis adds an average of two years to a patient's life.

1 Nov 2024

3D tumor mapping reveals new insights into cancer biology and treatment

A new analysis led by researchers at Washington University School of Medicine in St. Louis has revealed detailed 3D maps of the internal structures of multiple tumor types. These cancer atlases reveal how different tumor cells - and the cells of a tumor's surrounding environment - are organized, in 3D, and how that organization changes when a tumor spreads to other organs.

1 Nov 2024

Mapping tumor microenvironments: Uncovering spatial subclones for improved cancer treatment

Researchers investigate the spatial organization of cancer cells and the tumor microenvironment.

31 Oct 2024

Research identifies key factors in initiating tumor dormancy

A new research paper was published in Oncotarget's Volume 15 on October 11, 2024, entitled "Initiation of tumor dormancy by the lymphovascular embolus."

30 Oct 2024

3D-printed bone model offers new possibilities for surgery

University of Texas at Dallas mechanical engineers have designed a 3D-printed femur that could help doctors prepare for surgeries to repair bones and develop treatments for bone tumors.

30 Oct 2024

Successful treatment of metastatic malignant glomus tumor with BRAF and MEK inhibitors

A new case report was published in Oncotarget's Volume 15 on October 11, 2024, entitled "Complete response to encorafenib plus binimetinib in a BRAF V600E-mutant metastasic malignant glomus tumor."

29 Oct 2024

Researchers develop new approach to predict immunotherapy response in breast cancer patients

Using computational tools, researchers from the Johns Hopkins Kimmel Cancer Center and the Johns Hopkins University School of Medicine have developed a method to assess which patients with metastatic triple-negative breast cancer could benefit from immunotherapy.

29 Oct 2024

Tiny particles deliver combined heat and chemotherapy to tumors

Patients with late-stage cancer often have to endure multiple rounds of different types of treatment, which can cause unwanted side effects and may not always help.

29 Oct 2024