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LYNPARZA Phase III SOLO-1 results show improved outcome for patients with advanced BRCA-mutated ovarian cancer

AstraZeneca and Merck & Co., Inc., Kenilworth, N.J., today announced detailed results from the Phase III SOLO-1 trial testing LYNPARZA (olaparib) 300 mg tablets twice-daily as a maintenance treatment for patients with newly diagnosed advanced BRCA-mutated ovarian cancer who were in complete or partial response following 1st-line standard platinum-based chemotherapy.

22 Oct 2018

Merck presents KEYNOTE-057 trial results for patients with high-risk non-muscle invasive bladder cancer

Merck, known as MSD outside the United States and Canada, today announced the first presentation of results from an interim analysis of KEYNOTE-057, a Phase 2 trial evaluating KEYTRUDA, Merck's anti-PD-1 therapy, for previously treated patients with high-risk non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ or CIS plus papillary disease (Cohort A).

22 Oct 2018

FDA approves update to Rituxan label to include information on treatment of rare forms of vasculitis

Genentech, a member of the Roche Group, announced today that the U.S. Food and Drug Administration has approved an update to the Rituxan® (rituximab) label to include information on follow up treatment of adult patients with Granulomatosis with Polyangiitis and Microscopic Polyangiitis who have achieved disease control with induction treatment.

22 Oct 2018

Vertex gets European CHMP positive opinion for KALYDECO to treat patients with cystic fibrosis

Vertex Pharmaceuticals (Europe) Limited today announces that the European Medicines Agency's Committee for Medicinal Products for Human Use adopted a positive opinion for KALYDECO (ivacaftor) to include the treatment of people with cystic fibrosis (CF) aged 12 to <24 months who have at least one of the following nine mutations in their cystic fibrosis transmembrane conductance regulator gene: G551D, G1244E, G1349D, G178R, G551S, S1251N, S1255P, S549N or S549R.

22 Oct 2018

Takeda announces positive Phase 3 ALTA-1L data in first-line therapy for advanced ALK+ NSCLC

Takeda Pharmaceutical Company Limited today announced that intracranial efficacy data from the Phase 3 ALTA-1L (ALK in Lung Cancer Trial of BrigAtinib in 1st Line) trial showed improved intracranial progression-free survival (PFS) and intracranial objective response rate (ORR) with ALUNBRIG (brigatinib) compared to crizotinib among anaplastic lymphoma kinase-positive (ALK+) non-small cell lung cancer (NSCLC) patients.

22 Oct 2018

Deaths related to air pollution in the U.S. decreased by 47% between 1990 and 2010

Air pollution in the U.S. has decreased since about 1990, and a new study conducted at the University of North Carolina at Chapel Hill now shows that this air quality improvement has brought substantial public health benefits.

20 Oct 2018

Newly discovered compound shows potential for treating Parkinson's disease

A joint research group centered around Professor Hideyuki Okano and Associate Professor Jun Kohyama, Department of Physiology of the Keio University School of Medicine, together with a research group of Eisai Co., Ltd. has identified a compound that has the potential to be a treatment for Parkinson's disease by using dopaminergic neurons differentiated from induced pluripotent stem (iPS) cells from patients with familial Parkinson's disease.

19 Oct 2018

Muscle mass plays a critical role in health, shows research

Adults go to the doctor roughly three times a year. During their visit, vitals are taken such as blood pressure, pulse, and weight, but are these measurements really showing the full picture of a person's overall health?

19 Oct 2018

Cases of Acute Flaccid Myelitis on the rise across U.S.

According to the Centre for Disease Prevention and Control (CDC), cases of dangerous and rare Acute Flaccid Myelitis (AFM) are being noted across United States. This disease manifests similar to acute flaccid paralysis caused by polio virus say the experts. There is at present no treatment for this condition that primarily affects children and leads to paralysis of the limbs.

18 Oct 2018

Mysterious polio-like illness baffles medical experts while frightening parents

A spike in the number of children with a rare neurological disease that causes polio-like symptoms has health officials across the country scrambling to understand the illness. Yet, more than four years after health officials first recorded the most recent uptick in cases, much about the national outbreak remains a mystery.

17 Oct 2018

Reliable Respiratory announces acquisition of Attleboro Area Medical Equipment

Reliable Respiratory, one of New England's leading home respiratory and specialty medical equipment providers, today announced the acquisition of Attleboro Area Medical Equipment of Attleboro, Mass.

17 Oct 2018

Elective induction of labor at 39 weeks may be beneficial option for women and their babies

As the prevalence of maternal and fetal complications increases with advancing pregnancy beyond 39 weeks, induction of labor at 39 weeks has been proposed as a means to ensure optimal maternal and newborn health.

17 Oct 2018

Health effects of smoke-filled atmosphere

Every day, every human on the planet is exposed to one of the most toxic substances we know. However, it's largely invisible and most people don't know whether they need to worry. In new book Particles in the Air, Doug Brugge aims to raise awareness of serious consequences for public health.

16 Oct 2018

Research provides a more complete picture of suffering caused by terrorist attacks

Terrorist attacks injure far more people than they kill, leaving victims with lost limbs, hearing loss, respiratory disease, depression and other issues. But little research has measured the impact of that damage beyond the number of people who are hurt.

15 Oct 2018

Research shows basophils are key players in lung development

Lungs are vital organs required for the uptake of oxygen in exchange for carbon dioxide. However, the enormous complexity of the respiratory organ is often underestimated and deserves a closer look: A broad range of specialized cells work closely together to ensure the proper functioning of the lung and provide the vital gas exchange.

12 Oct 2018

Synspira’s abstracts accepted for presentation at the 32nd Annual NACFC

Synspira, a privately held company developing a new class of inhaled glycopolymer-based therapeutics for the treatment of pulmonary disease, today announced that three abstracts have been accepted for presentation at the 32nd Annual North American Cystic Fibrosis Conference, occurring October 18-20 in Denver, CO.

12 Oct 2018

Respiratory News and Research

LYNPARZA Phase III SOLO-1 results show improved outcome for patients with advanced BRCA-mutated ovarian cancer

Merck presents KEYNOTE-057 trial results for patients with high-risk non-muscle invasive bladder cancer

FDA approves update to Rituxan label to include information on treatment of rare forms of vasculitis

Vertex gets European CHMP positive opinion for KALYDECO to treat patients with cystic fibrosis

Takeda announces positive Phase 3 ALTA-1L data in first-line therapy for advanced ALK+ NSCLC

Deaths related to air pollution in the U.S. decreased by 47% between 1990 and 2010

Newly discovered compound shows potential for treating Parkinson's disease

Muscle mass plays a critical role in health, shows research

Cases of Acute Flaccid Myelitis on the rise across U.S.

Mysterious polio-like illness baffles medical experts while frightening parents

Reliable Respiratory announces acquisition of Attleboro Area Medical Equipment

Elective induction of labor at 39 weeks may be beneficial option for women and their babies

Health effects of smoke-filled atmosphere

Research provides a more complete picture of suffering caused by terrorist attacks

Research shows basophils are key players in lung development

Synspira’s abstracts accepted for presentation at the 32nd Annual NACFC

Basophils play key role in development of macrophages in the lung

Retia Medical Introduces World Renowned Clinical Advisory Board

Researchers identify molecule that plays key role in bacterial communication, infection

Long-term ozone exposure linked to adverse health effects

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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