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Researchers have coaxed RNA to self-assemble into 3-D arrays

These RNA structures can form a wider variety of shapes than double-stranded DNA can and are easier to manipulate than many protein alternatives.

23 Aug 2004

Computer model of damaged DNA bends the rules

Our knees may become stiff when injured, but banged up DNA becomes flexible, suggests the most detailed computer model of damaged DNA to date. Further, this flexibility explains how the body's enzymes recognize and fix damaged DNA.

23 Aug 2004

Nitroxyl-releasing drugs promise to revive failing hearts

Half a million Americans are diagnosed each year with heart failure, a progressively debilitating condition characterized by the heart's declining ability to pump blood efficiently.

22 Aug 2004

Small molecules as artificial gene regulators

Scientists have been trying for some time to develop molecules that mimic natural regulators of gene expression.

22 Aug 2004

Existing hepatitis drug could lead to the development of new drugs for the treatment of anthrax

Thanks to new screening tools, and some luck, researchers at the University of Chicago have discovered three unrelated compounds that inhibit the two toxins – edema factor and lethal factor -- that have made anthrax one of the most feared of potential bioterror agents.

21 Aug 2004

Newly discovered protein switch may be key to understanding sleep disorders, anxiety, and depression

University of California researchers have found that a newly discovered protein switch which they named neuropeptide S appears to work in the brain to enhance wakefulness and reduce anxiety in laboratory animals. According to Rainer Reinscheid and his colleagues, the protein could help in the understanding of sleep disorders, anxiety, and depression.

18 Aug 2004

Scientists visualise protein complex responsible for looking after out of shape proteins

The structure of the chaperonin complex of the bacteria Thermus thermophilus reveals clues about how the important molecule may do its job of folding new or damaged proteins within cells.

17 Aug 2004

Scientists have uncovered the identity of the last of eight genes known to contribute to Bardet-Biedl syndrome

The identification of the BBS3 gene ends the search for primary BBS-causing genes in families studied for years by a team of scientists from the United States, Canada and the United Kingdom. However, the scientists are still hunting for other, less obvious genetic influences in these families.

16 Aug 2004

The prion appears to function as an evolutionary stepping stone

“This prion,” explains Lindquist, “has a capacity to hide and release genetic information throughout the entire genome that can contribute to new traits in a complex way.”

16 Aug 2004

New imaging technique may help cystic fibrosis sufferers

Now, Jefferson Lab scientists have used their expertise to build a small animal medical imager that's helping researchers develop a new gene therapy technique for cystic fibrosis.

15 Aug 2004

Trick illustrates life’s determination to survive hostile environments

Dipping your hands into 160-degree water is guaranteed to give you an immediate and severe scalding - unless you’re one of the few species of bacteria that manage to thrive in temperatures that would maim or kill the rest of the Earth’s inhabitants.

13 Aug 2004

Researchers map structure of anti-cancer molecule and open the door to the creation of more effective cancer treatments

Scientists at Emory University, in collaboration with researchers at three national laboratories, have solved the structural puzzle of how an emerging class of promising cancer drugs works to halt cell division. The discovery potentially opens the door to the creation of more effective cancer treatments.

13 Aug 2004

Pineal gland which regulates the cycles of sleep and waking evolved to improve vision

The pineal gland - which regulates the cycles of sleep and waking - appears to have evolved as an indirect way to improve vision, by keeping toxic compounds away from the eye

13 Aug 2004

Microscopic scaffolding to house the tiny components of nanotech devices could be built from RNA

Microscopic scaffolding to house the tiny components of nanotech devices could be built from RNA, the same substance that shuttles messages around a cell's nucleus, reports a Purdue University research group.

12 Aug 2004

Self-assembling peptides, a breakthrough with enormous therapeutic potential

In the August 12 issue of the journal Nature, researchers at the University of Pennsylvania detail the creation of a library of small protein-like molecules that can self-assemble to form hollow corkscrew-like pores that could mimic pores seen in living systems.

11 Aug 2004

New service-oriented laboratory focused on bioanalysis and pharmacokinetics

Oregon Health & Science University researchers will more quickly move benchtop discoveries toward drug discoveries with the help of a new, service-oriented laboratory focused on bioanalysis and pharmacokinetics.

11 Aug 2004

Scientists have turned procrastinating primates into workaholics by temporarily suppressing a gene in a brain circuit involved in reward learning

Using a new molecular genetic technique, scientists have turned procrastinating primates into workaholics by temporarily suppressing a gene in a brain circuit involved in reward learning. Without the gene, the monkeys lost their sense of balance between reward and the work required to get it, say researchers at the National Institute of Mental Health .

11 Aug 2004

New direction for research into Sly Syndrome

Findings by a Saint Louis University research team led by the scientist who discovered Sly Syndrome 32 years ago point to a new direction for research into the rare genetic disorder that can cause bone deformities, vision and hearing loss, mental retardation and death in children.

9 Aug 2004

Promising families of drugs combat the spread of tumors in different ways

Pharmaceutical companies seeking to design more effective cancer chemotherapy agents may have an easier road ahead than was previously believed.

9 Aug 2004

New fluorescent dye technique may provide new insight into how cancerous tumors begin and grow

A technique developed by University of California, San Diego biologists, which uses bright fluorescent dyes to reveal the activity of genes in individual cells of an organism, promises to be a boon to developmental biologists, and may provide new insight into how cancerous tumors begin and grow.

6 Aug 2004

Molecule News and Research

Researchers have coaxed RNA to self-assemble into 3-D arrays

Computer model of damaged DNA bends the rules

Nitroxyl-releasing drugs promise to revive failing hearts

Small molecules as artificial gene regulators

Existing hepatitis drug could lead to the development of new drugs for the treatment of anthrax

Newly discovered protein switch may be key to understanding sleep disorders, anxiety, and depression

Scientists visualise protein complex responsible for looking after out of shape proteins

Scientists have uncovered the identity of the last of eight genes known to contribute to Bardet-Biedl syndrome

The prion appears to function as an evolutionary stepping stone

New imaging technique may help cystic fibrosis sufferers

Trick illustrates life’s determination to survive hostile environments

Researchers map structure of anti-cancer molecule and open the door to the creation of more effective cancer treatments

Pineal gland which regulates the cycles of sleep and waking evolved to improve vision

Microscopic scaffolding to house the tiny components of nanotech devices could be built from RNA

Self-assembling peptides, a breakthrough with enormous therapeutic potential

New service-oriented laboratory focused on bioanalysis and pharmacokinetics

Scientists have turned procrastinating primates into workaholics by temporarily suppressing a gene in a brain circuit involved in reward learning

New direction for research into Sly Syndrome

Promising families of drugs combat the spread of tumors in different ways

New fluorescent dye technique may provide new insight into how cancerous tumors begin and grow

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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