Heart Attack (Myocardial Infarction) News and Research

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A Heart Attack (Myocardial Infarction) occurs when blood flow to a section of heart muscle becomes blocked. If the flow of blood isn’t restored quickly, the section of heart muscle becomes damaged from lack of oxygen and begins to die.

Heart attack is a leading killer of both men and women in the United States. But fortunately, today there are excellent treatments for heart attack that can save lives and prevent disabilities. Treatment is most effective when started within 1 hour of the beginning of symptoms. Heart attacks occur most often as a result of a condition called coronary artery disease (CAD). In CAD, a fatty material called plaque (plak) builds up over many years on the inside walls of the coronary arteries (the arteries that supply blood and oxygen to your heart). Eventually, an area of plaque can rupture, causing a blood clot to form on the surface of the plaque. If the clot becomes large enough, it can mostly or completely block the flow of oxygen-rich blood to the part of the heart muscle fed by the artery.

Simvastatin linked to protection against endothelial dysfunction in diabetic rats

Almost two years ago, the diabetes arm of the Heart Protection Study, the largest-ever study using a cholesterol-lowering medication, found that diabetics who took a daily dose of the statin drug simvastatin over five years reduced the risk of a first nonlethal heart attack by 37 percent and risk of a first nonfatal or fatal stroke by 24 percent, regardless of their cholesterol or glucose levels.

3 Apr 2005

Discovery could lead to new drug targets for heart disease

Mice with glowing green hearts have yielded the latest clue in the search for molecules involved in structural heart disease. Vanderbilt University Medical Center investigators found that blocking the activity of a single protein, called CaM kinase, in the mouse heart protects against the damaging effects of a heart attack.

30 Mar 2005

Important link between kidney damage and cardiac problems

Scientists have identified an important link between kidney damage and cardiac problems, creating new possibilities for treating the primary cause of death in kidney disease patients.

29 Mar 2005

Optical coherence tomography (OCT) can successfully identify the characteristics of coronary plaques

A catheter-based imaging technology called optical coherence tomography (OCT) can successfully identify the characteristics of coronary plaques in patients with various cardiac symptoms. The report from researchers at Massachusetts General Hospital (MGH) will appear in the journal Circulation.

29 Mar 2005

Pcsk9 gene - new target for cholesterol-lowering drugs

Mice lacking a key protein involved in cholesterol regulation have low-density lipoprotein, or "bad" cholesterol, levels more than 50 percent lower than normal mice, and researchers suggest that inhibiting the same protein in humans could lead to new cholesterol-lowering drugs.

29 Mar 2005

Heart attacks can be triggered by physical exertion and emotional stress

Philip Strike and Andrew Steptoe of University College London, in a review published in the current issue of Psychosomatic Medicine, of dozens of studies done between 1970 and 2004 have come up with compelling evidence that indicates that people with a history of heart disease, can trigger heart attacks, some of them fatal, by physical exertion and emotional stress.

23 Mar 2005

Treatment of cardiac lesions without anaesthesic

Navarre University Hospital has introduced a novel technique for the treatment of congenital heart defects and involving the percutaneous closure of the patent foramen ovale (PFO) with monitoring through intracavernous ecography.

23 Mar 2005

Physical exertion and emotional stress can trigger heart attacks in people with a history of heart disease

Authors Philip Strike and Andrew Steptoe of University College London point out that the triggers for heart attacks may be quite different from the factors that lead to development of coronary heart disease over the long term, such as cigarette smoking, lack of exercise, work stress, social isolation, anxiety and depression.

22 Mar 2005

Bush intervenes in Terri Schiavo case

Terri Schiavo, has been in a permanent vegetative state which is far more severe than a coma, since she had a heart attack in 1990 that deprived her brain of oxygen.

21 Mar 2005

Calls to regionalize the care of patients with heart attacks are premature

Calls to regionalize the care of patients with heart attacks are premature, and do not account for potential unintended consequences, according to a commentary by Yale researchers published in the Journal of the American Medical Association (JAMA).

21 Mar 2005

Rapid rise in obesity may reverse life expectancy trend

It's been assumed that U.S. life expectancy would rise indefinitely, but a new data analysis, published as a special report in the March 17 New England Journal of Medicine, suggests that this trend is about to reverse itself -- due to the rapid rise in obesity, especially among children.

21 Mar 2005

Link between C-reactive protein, heart disease and stroke

The cells that line the arteries are able to produce C-reactive protein, according to a study funded by the National Institutes of Health and published in the April issue of American Journal of Pathology.

16 Mar 2005

Antidepressants not the culprit in depression linked to heart attacks

The increased risk of heart attack associated with taking antidepressants may be caused by the depression itself rather than the drugs themselves, suggests new research reported in the current issue in the British Medical Journal. At least one in 10 older people are prescribed antidepressants.

15 Mar 2005

Drug therapy may be comparable to invasive cardiac procedures for elderly patients with heart attack

Although the type and intensity of treatment for acute myocardial infarction (AMI) [heart attack] varies widely across the country, elderly patients who receive intensive medical treatment may have comparable survival as those who undergo invasive cardiac procedures (such as angioplasty and bypass surgery), according to a study in the March 16 issue of JAMA.

15 Mar 2005

Research, advocacy and education must "close the gaps" in cardiovascular health disparities

Research, advocacy and education must "close the gaps" in cardiovascular health disparities among races, an American Heart Association writing group reports in today's special disparities issue of Circulation: Journal of the American Heart Association.

15 Mar 2005

Knowledge of stroke warning signs remains low among U.S. women

Knowledge of stroke warning signs remains low among U.S. women, particularly among racial and ethnic minorities, according to a national survey reported in a special disparities themed issue of Circulation: Journal of the American Heart Association.

15 Mar 2005

Blacks less likely to get expensive, newer heart treatments

Blacks who suffer the most common type of cardiac ischemia – non-ST-elevation acute coronary syndrome – are less likely than whites to receive expensive or newer evidence-based treatments, according to a report in a special disparities themed issue of Circulation: Journal of the American Heart Association.

15 Mar 2005

Health care report cards may increase racial/ethnic disparities in bypass operations

Medical "report cards" intended to improve the quality of health care may sometimes reduce it for racial and ethnic minorities, according to a report in a special disparities themed issue of Circulation: Journal of the American Heart Association.

15 Mar 2005

Community care tops medical care at preventing heart disease in black Americans

Upgraded community health services, including checkups by phone or in person with a local nurse practitioner at a neighborhood clinic, and free charge cards for medications are almost nine times more likely to benefit black Americans at greater risk of heart disease than full-service physician care alone.

15 Mar 2005

Heart disease risk in older women identified by simple blood test

Postmenopausal women who are not identified by traditional cardiovascular risk factors, could benefit from a simple blood test to show their white blood cell (WBC) count which may predict cardiovascular events and risk of death.

15 Mar 2005