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Study provides new hope for future treatment of intestinal condition IBS

Researchers at örebro University in Sweden have made a significant advance in understanding the intestinal condition IBS.

2 Dec 2025

Generative AI aids discovery of ISM3830's novel scaffold

Casitas B-lineage lymphoma-b (CBLB) is an E3 ubiquitin–protein ligase that functions as an intracellular checkpoint and master negative regulator of T‑cell and natural killer (NK) cell activation, playing a central role in modulating T-cell activation and immune tolerance, and its inhibition enhances T cells and NK cells function, also provides a strategy for the function restoration of exhausted T cells.

1 Dec 2025

Study links endocrine-disrupting chemicals to hidradenitis suppurativa

A Johns Hopkins Medicine study involving a dozen people with the inflammatory skin disease hidradenitis suppurativa (HS), which mostly affects skin folds, is believed to be the first to provide evidence that hormone-disrupting chemicals commonly found in ultra-processed food and single-use water bottles may contribute to the development of or worsen the condition in some people.

1 Dec 2025

Study reveals ATM kinase as the key driver of replicative senescence

After a finite number of divisions, cells simply give up. As each round of replication trims their telomeres-the protective caps at the chromosome ends-those caps eventually become too short to prevent chromosome ends from being recognized as DNA breaks.

1 Dec 2025

Machine learning tool identifies compounds that induce cancer cells into senescence

A new research paper featured on the cover of Volume 17, Issue 11 of Aging-US was published on October 30, 2025, titled "SAMP-Score: a morphology-based machine learning classification method for screening pro-senescence compounds in p16 positive cancer cells."

1 Dec 2025

Latent antimicrobial resistance found to be more widespread across the world

A team of researchers has discovered that latent antimicrobial resistance is more widespread across the world than known resistance.

1 Dec 2025

Tiny metal particles can kill cancer cells while leaving healthy cells unharmed

An international research team led by RMIT University have created tiny particles, known as nanodots, made from a metallic compound that can kill cancer cells while leaving healthy cells largely unharmed.

1 Dec 2025

Why green tea delivers the strongest health benefits

This review examines tea's health effects, highlighting green tea's benefits for heart health and cognition, and warns about risks in processed tea products.

1 Dec 2025

New AI tools offer hope for global TB elimination

Researchers have unveiled new AI tools, from smartphone cough analysis to child-friendly screening systems, which could transform how tuberculosis is detected, monitored and prevented.

1 Dec 2025

Measles deaths plummet but infections surge worldwide

Global immunization efforts have led to an 88% drop in measles deaths between 2000 and 2024, according to a new report from the World Health Organization (WHO). Nearly 59 million lives have been saved by the measles vaccine since 2000.

29 Nov 2025

Fanconi anemia patients show striking metabolic differences

Experts at Cincinnati Children's have uncovered striking metabolic differences in people with Fanconi anemia (FA), a rare genetic disorder that causes bone marrow failure and dramatically increases cancer risk.

29 Nov 2025

Early-infancy infection with RSV increases the risk of developing childhood asthma

Belgian scientists from VIB and Ghent University (UGent), together with Danish collaborators, have uncovered compelling evidence that early-infancy infection with respiratory syncytial virus (RSV) significantly increases the risk of developing childhood asthma-especially in children with a family history of allergy or asthma.

29 Nov 2025

Fu's subcutaneous needling offers a safe non-pharmacological therapy for muscle-related pain

Chronic muscle tension is a common underlying factor in many pain disorders, causing reduced arterial blood flow, tissue hypoxia, and the release of inflammatory mediators.

28 Nov 2025

Blocking a ‘gerozyme’ reverses cartilage loss in mice

An injection that blocks the activity of a protein involved in aging reverses naturally occurring cartilage loss in the knee joints of old mice, a Stanford Medicine-led study has found.

28 Nov 2025

Fever-resistant bird flu viruses pose a significant threat to humans

Bird flu viruses are a particular threat to humans because they can replicate at temperatures higher than a typical fever, one of the body's ways of stopping viruses in their tracks, according to new research led by the universities of Cambridge and Glasgow.

28 Nov 2025