Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

Study identifies key role of TLK1 and TLK2 enzymes in DNA replication

During cell growth, cells copy their DNA through a process called DNA replication. For this process to be accurate, the genetic and epigenetic information must be copied flawlessly.

9 Aug 2018

Silencing of GULP1 gene expression plays important role in ovarian carcinogenesis

Johns Hopkins researchers in collaboration with Insilico Medicine, a biotechnology company based in Rockville Maryland, identify that silencing of the GULP1 gene expression by methylation plays an important role in ovarian carcinogenesis.

7 Aug 2018

Offspring fed with low-protein diet during pregnancy more likely to develop prostate cancer

The offspring of females fed a low-protein diet during pregnancy and lactation are significantly more likely to develop prostate cancer as they age.

7 Aug 2018

Claudia Langenberg wins Helmholtz International Fellow Award

"Claudia Langenberg is known for her research on genetic causes of insulin resistance, type 2 diabetes and related metabolic disorders," explains Dr. Gabi Kastenmüller, acting head of the Institute of Bioinformatics and Systems Biology.

3 Aug 2018

Cancer cells proliferate less when their internal pH is lowered, study shows

A new computational model has allowed researchers to identify new therapeutic targets that can attack cancer cells by lowering their intracellular pH. The study, which is the result of collaboration between IRB Barcelona, the Moffitt Cancer Center, and the University of Maryland, has been published in Nature Communications.

31 Jul 2018

Pungent compound contained in ginger ensures fresh breath

The pungent compound 6-gingerol, a constituent of ginger, stimulates an enzyme contained in saliva - an enzyme which breaks down foul-smelling substances.

30 Jul 2018

Researchers discover novel antibiotic from leaf of common weed

Researchers working on an SNSF project have discovered novel, antibiotically active chemical substances in a previously rarely explored site: the leaf of a common field weed.

27 Jul 2018

Novel tool predicts genes that cause disease due to production of truncated proteins

Predicting genes that can cause disease due to the production of truncated or altered proteins that take on a new or different function, rather than those that lose their function, is now possible thanks to an international team of researchers, including researchers from Baylor College of Medicine, that has developed a new analytical tool to effectively and efficiently predict such candidate genes.

20 Jul 2018

Top AI companies join hands to discover novel drugs for DMD

Insilico Medicine a leader in artificial intelligence for drug discovery, biomarker development and aging research, announced a research collaboration agreement with A2A Pharmaceuticals, Inc. A2A is a biotechnology company headquartered in New York and focused on development of novel drugs for unmet needs in oncology, drug resistant bacterial infections, and other life threatening diseases.

20 Jul 2018

Bioengineers, diabetes researchers convene to discuss future concepts for precision medicine

New technologies enable deeper insights into the causes of major diseases such as diabetes, obesity or cancer and open the way to a new generation of diagnostics and therapies.

17 Jul 2018

New research lays foundation to create standards for RNA sequencing

The idea of testing blood or urine to find markers that help diagnose or treat disease holds great promise. But as technology has improved to allow researchers to examine tiny fragments of RNA, one major problem has led to limited success.

17 Jul 2018

Study demonstrates new therapeutic targets for inflammation-associated colon cancer

Scientists headed by ICREA researcher Angel R. Nebreda at the Institute for Research in Biomedicine (IRB Barcelona) report a new mechanism that contributes to the development of inflammation-associated colon cancer and points to new therapeutic targets. The study has been published in the journal EMBO Molecular Medicine.

12 Jul 2018

Novel informatics tool helps predict genomic features associated with specific drug responses

The rise of genomics, the shift from considering genes singly to collectively, is adding a new dimension to medical care; biomedical researchers hope to use the information contained in human genomes to make better predictions about individual health, including responses to therapeutic drugs.

12 Jul 2018

Scientists pinpoint new therapeutic targets for inflammation-associated colon cancer

Scientists headed by ICREA researcher Angel R. Nebreda at the Institute for Research in Biomedicine report a new mechanism that contributes to the development of inflammation-associated colon cancer and points to new therapeutic targets

11 Jul 2018

Researchers attempt to create better diagnostic test for radiation exposure

Researchers at the University of Arizona College of Medicine - Phoenix are attempting to create a better diagnostic test for radiation exposure that potentially could save thousands of lives.

11 Jul 2018

Researchers develop first comprehensive atlas of lung tumor cells

Researchers from VIB, Leuven University and University Hospital Leuven studied thousands of healthy and cancerous lung cells to create the first comprehensive atlas of lung tumor cells.

10 Jul 2018

Widespread transfer of genes between species appears to be key driver of evolution

Far from just being the product of our parents, University of Adelaide scientists have shown that widespread transfer of genes between species has radically changed the genomes of today's mammals, and been an important driver of evolution.

9 Jul 2018

Cleara Biotech creates three public-private partnerships to discover and develop new therapeutics

Cleara Biotech B.V., a Netherlands-based biopharmaceutical company, announced today the creation of three public-private partnerships to discover and develop new therapeutics.

6 Jul 2018

Mother's diet during pregnancy may impact baby's gut microbiome, shows study

A mother's diet during pregnancy may have an effect on the composition of her baby's gut microbiome - the community of bacteria living in the gut - and the effect may vary by delivery mode, according to study published in the open access journal Microbiome.

5 Jul 2018

New algorithm predicts patients who will benefit from high blood pressure treatment

Using data from large clinical trials, UT Southwestern researchers developed a way to predict which patients will benefit most from aggressive high blood pressure treatment.

3 Jul 2018

Bioinformatics News and Research

Further Reading

Study identifies key role of TLK1 and TLK2 enzymes in DNA replication

Silencing of GULP1 gene expression plays important role in ovarian carcinogenesis

Offspring fed with low-protein diet during pregnancy more likely to develop prostate cancer

Claudia Langenberg wins Helmholtz International Fellow Award

Cancer cells proliferate less when their internal pH is lowered, study shows

Pungent compound contained in ginger ensures fresh breath

Researchers discover novel antibiotic from leaf of common weed

Novel tool predicts genes that cause disease due to production of truncated proteins

Top AI companies join hands to discover novel drugs for DMD

Bioengineers, diabetes researchers convene to discuss future concepts for precision medicine

New research lays foundation to create standards for RNA sequencing

Study demonstrates new therapeutic targets for inflammation-associated colon cancer

Novel informatics tool helps predict genomic features associated with specific drug responses

Scientists pinpoint new therapeutic targets for inflammation-associated colon cancer

Researchers attempt to create better diagnostic test for radiation exposure

Researchers develop first comprehensive atlas of lung tumor cells

Widespread transfer of genes between species appears to be key driver of evolution

Cleara Biotech creates three public-private partnerships to discover and develop new therapeutics

Mother's diet during pregnancy may impact baby's gut microbiome, shows study

New algorithm predicts patients who will benefit from high blood pressure treatment

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