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Chokeberry juice reduces blood vessel resistance in people with pre-diabetes

A German crossover trial found that drinking polyphenol-rich red berry juice improved peripheral resistance and helped preserve muscle mass in pre-diabetic adults. No significant changes were seen in glucose control or oxidative stress over the 14-day interventions.

12 May 2025

Researchers uncover how Entamoeba histolytica evades the immune system

The single-celled parasite Entamoeba histolytica infects 50 million people each year, killing nearly 70,000. Usually, this wily, shape-shifting amoeba causes nothing worse than diarrhea.

12 May 2025

Intermittent fasting may dampen inflammatory responses in the gums

New research presented today at EuroPerio11, the world's leading congress in periodontology and implant dentistry by the European Federation of Periodontology (EFP), suggests that intermittent fasting could help reduce inflammation in the gums and improve certain health markers, even when oral hygiene is temporarily neglected.

12 May 2025

Millions of women may be unaware of their risk for cardiovascular-kidney-metabolic disease

Millions of women may be unknowingly living with risk factors for heart, kidney and metabolic disease – interconnected conditions that together drive risk for cardiovascular disease, the leading cause of death among women, according to experts with the American Heart Association, a global force changing the future of health for all.

12 May 2025

Research sheds light on the profound connections between diet, inflammation, and gum health

New research presented at EuroPerio11 sheds light on the profound connections between diet, inflammation, and gum health.

12 May 2025

Breakthrough discovery offers hope for treating neurodegenerative diseases

Researchers have discovered how to block cells dying, in a finding that could lead to new treatments for neurodegenerative conditions like Parkinson's and Alzheimer's.

12 May 2025

PhoreMost makes key appointments to Board to advance development of next-generation degrader therapeutics

PhoreMost Ltd., a next-generation targeted protein degradation (TPD) company progressing a pipeline of degrader therapeutics within oncology and inflammation, today announced Barbara Duncan has joined its Board as Chair, and Stephen Dilly as Non-Executive Director.

From PhoreMost 12 May 2025

ELRIG announces keynote speakers for Drug Discovery 2025

ELRIG, a not-for-profit, volunteer-led organization dedicated to the global drug discovery community, has revealed the keynote speakers for its flagship event, Drug Discovery 2025. Taking place at the ACC in Liverpool, UK from 21-22 October, the conference will feature presentations from Professor Heather Pinkett (Northwestern University) and Dr Dafydd Owen (Pfizer Medicine Design).

From ELRIG (UK) Ltd. 12 May 2025

Adverse waist-to-height ratio trajectories during childhood linked to early cardiometabolic risk

New research being presented at this year's European Congress on Obesity (ECO) in Malaga, Spain (11-14 May) reveals that adverse waist-to-height ratio trajectories (a marker for central obesity) during childhood may increase cardiometabolic and cardiovascular risk at 10 years old.

11 May 2025

Scientists link specific gene variants to post-vaccine myocarditis and pericarditis

A genome-wide association study in Sweden identified rare genetic variants near the SCAF11 and LRRC4C genes that may be linked to heart inflammation following COVID-19 mRNA vaccination. The findings shed light on potential biological pathways driving vaccine-associated myocarditis and pericarditis, particularly among younger individuals.

11 May 2025

New AI tool predicts viral mutations to help future-proof COVID vaccines

A novel AI-driven method helps scientists stay ahead of viral evolution by engineering synthetic spike proteins that anticipate future SARS-CoV-2 escape mutations, offering a powerful tool to test and strengthen next-generation vaccines.

11 May 2025

Blocking LSD1 restores immune response in early oral cancer

Oral squamous cell carcinoma (OSCC) is a leading cause of cancer-related deaths, and early detection is key to improving patient outcomes. However, the mechanisms driving the transition from preneoplastic lesions to full-blown cancer are not well understood.

11 May 2025

DNA strand separation requires more force in crowded cellular environments

By creating a more true-to-life representation of DNA's environment, researchers at Northwestern University have discovered that strand separation - the essential process a "resting" double helix undergoes before it can initiate replication or make repairs - may take more mechanical force than the field previously believed.

11 May 2025

Newly identified gene mutation causes severe form of Fanconi anemia

Fanconi anemia is an aggressive, life-threatening disorder. Most individuals living with this rare genetic condition, characterized by bone marrow failure and cancer predisposition, survive into adulthood only with bone marrow transplantation and regular cancer screening.

11 May 2025

MicroRNA breakthrough offers hope for dental bone regeneration

Dental caries, or tooth decay, is a common oral health condition that often causes significant pain and discomfort and may even lead to tooth loss.

8 May 2025

UC engineers develop saliva test to detect depression and anxiety

University of Cincinnati engineers created a new device to help doctors diagnose depression and anxiety.

8 May 2025

Long-acting HIV drug emerges from decades of research and advocacy

In the hunt for a remedy, when the baton is passed from dedicated academic scientists to an innovative company to trusted community advocates, outcomes for society can be especially powerful.

8 May 2025

Obicetrapib slashes LDL cholesterol by over 30% in high-risk heart patients

A large multinational trial published in the New England Journal of Medicine shows that obicetrapib significantly lowers LDL cholesterol in high-risk cardiovascular patients. The CETP inhibitor also improved key lipid parameters with no major safety concerns, supporting its role in future combination therapies.

8 May 2025

New brain imaging method shows promise for early diagnosis of Parkinson's disease

An international team, led by researchers at the Champalimaud Foundation (CF), has shown – for the first time in a realistic way – that it may be possible to diagnose Parkinson's disease (PD) years before it becomes untreatable, by scanning people's brains with functional magnetic resonance imaging (fMRI).

8 May 2025

New workflow enhances detection of low-abundant glycoproteins in blood plasma

A recent study published in Engineering presents a novel approach to analyzing the low-abundant N-glycoproteome in human blood plasma (HBP), which could significantly advance the discovery of plasma biomarkers.

8 May 2025