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St. John's wort extract shows potent antiviral activity against SARS-CoV-2 and its variants

Scientists from Germany have recently identified Hypericum perforatum, a widespread herbal plant known as St. John's wort, as a potential antiviral agent against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The study is published in the journal Pharmaceuticals.

27 Apr 2022

The potency of halicin against the main protease of SARS-CoV-2

A new paper published in Current Research in Chemical Biology discusses the potential of a molecule called halicin against SARS-CoV-2.

26 Apr 2022

Quercetin and other plant flavonols show anti-SARS-CoV-2 activity

A new study discusses the potential of certain plant compounds to block SARS-CoV-2 replication within host cells.

24 Apr 2022

New tool delivers and electrically stimulates stem cells to promote stroke recovery

More than 10 million strokes occur worldwide every year, leaving at least half of patients with life-altering disabilities.

22 Apr 2022

Radioconjugates could transform the future of cancer care

Many current cancer treatments make patients very sick because even the most targeted treatments kill healthy cells as well as cancer cells. But a new type of treatment called a radioconjugate is getting the attention of oncologists.

20 Apr 2022

Leica Microsystems wins distinctive Red Dot design award

Leica Microsystems, a leading provider of microscopy and scientific instruments, has won a 2022 Red Dot Award for its digital inspection microscope, Emspira 3.

From Leica Microsystems GmbH 20 Apr 2022

Copycat cannabis edibles could be attractive to children and increase risk for accidental ingestion

Some cannabis edibles look remarkably like popular snack foods and may be easily confused for them, finds a new study led by researchers at NYU School of Global Public Health published in Drug and Alcohol Dependence.

19 Apr 2022

Using customized 'mini-antibodies' to mitigate chronic inflammation

Researchers at the Universities of Bonn and Sao Paulo have succeeded in mitigating chronic inflammation in mice using customized "mini-antibodies."

19 Apr 2022

Study predicts that different statins exhibit divergent effects on host response to SARS-CoV-2 infection

A new study explores the possibility that different statins may exhibit different effects within the host and may differ in their outcomes while treating COVID-19 patients.

18 Apr 2022

The preclinical potential of S. miltiorrhiza extracts for the treatment of COVID-19

In a recent study, researchers assessed the anti-COVID-19 efficacy of Salvia miltiorrhiza Bunge.

14 Apr 2022

Innovative imaging technique may pave the way for better understanding and treatment of spinal cord injury

A research team led by scientists from the Hong Kong University of Science and Technology has developed an innovative technology for in vivo imaging of the important biological processes involved in the injury and repair of spinal cords, paving the way for a better understanding of the pathology and potential treatment of spinal cord injury (SCI).

12 Apr 2022

Research using kidney organoids may lead to new targets to help prevent or treat CKD

To a certain extent, kidneys have the capacity to repair themselves after being injured, but a switch can occur from such intrinsic repair to incomplete repair that leads to irreversible damage and chronic kidney disease (CKD).

12 Apr 2022

New research provides a scientific framework to allow the use of psilocybin for therapeutic reasons

A new paper by an Oregon State University-led research team provides a scientific framework to help shape the rollout of a program in Oregon that will legally permit the use of psilocybin for therapeutic reasons.

11 Apr 2022

Magic mushroom compound helps to 'open up' depressed people's brains after use

Psilocybin, the psychedelic compound found in magic mushrooms, helps to "open up" depressed people's brains, even after use, enabling brain regions to talk more freely to one another.

11 Apr 2022

S-Nitrosylation of ACE2 inhibits binding of SARS-CoV-2 spike protein

In a recent study posted to the bioRxiv* preprint server, researchers developed aminoadamantane nitrates compounds that inhibit the ion channels formed by the envelope (E) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and enable targeted drug delivery of nitric oxide (NO)-related group for S-nitrosylation of host angiotensin-converting enzyme 2 (ACE2), which would inhibit ACE2 binding with the viral spike (S) protein and thereby inhibit viral replication in the host.

11 Apr 2022

A novel PLpro inhibitor as a broad-spectrum anti-coronavirus agent

Researchers identify a potentially effective compound against COVID-19 against the SARS-CoV-2 PLpro.

10 Apr 2022

Curcumin released from magnetic hydrogels promotes the secretion of vascular endothelial growth factor

A finding by UC Riverside bioengineers could hasten development of lab-grown blood vessels and other tissues to replace and regenerate damaged tissues in human patients. The results are published in ACS Applied Materials and Interfaces.

6 Apr 2022

Cryo-EM imaging of a key immune protein reveals previously unrecognized binding site

Imaging at near-atomic resolution of a key immune protein commonly known as STING has revealed a previously unrecognized binding site that appears to be pivotal for launching immune attacks, UT Southwestern scientists report in a new study.

6 Apr 2022

Developing and manufacturing custom recombinant antibodies for R&D

In this interview, Dr. Linlin Zhang, technical specialist for Sino Biological Europe, discusses how Sino is expanding its product offerings into the European market and outlines its process for developing and manufacturing custom recombinant antibodies for their clients.

From Sino Biological Inc. 6 Apr 2022

Sodium thiosulfate shows no benefits for reducing heart damage following a heart attack

Sodium thiosulfate showed no benefits for reducing injury to damaged areas of heart muscle following a heart attack, in a study presented at the American College of Cardiology's 71st Annual Scientific Session.

5 Apr 2022

Compound News and Research

St. John's wort extract shows potent antiviral activity against SARS-CoV-2 and its variants

The potency of halicin against the main protease of SARS-CoV-2

Quercetin and other plant flavonols show anti-SARS-CoV-2 activity

New tool delivers and electrically stimulates stem cells to promote stroke recovery

Radioconjugates could transform the future of cancer care

Leica Microsystems wins distinctive Red Dot design award

Copycat cannabis edibles could be attractive to children and increase risk for accidental ingestion

Using customized 'mini-antibodies' to mitigate chronic inflammation

Study predicts that different statins exhibit divergent effects on host response to SARS-CoV-2 infection

The preclinical potential of S. miltiorrhiza extracts for the treatment of COVID-19

Innovative imaging technique may pave the way for better understanding and treatment of spinal cord injury

Research using kidney organoids may lead to new targets to help prevent or treat CKD

New research provides a scientific framework to allow the use of psilocybin for therapeutic reasons

Magic mushroom compound helps to 'open up' depressed people's brains after use

S-Nitrosylation of ACE2 inhibits binding of SARS-CoV-2 spike protein

A novel PLpro inhibitor as a broad-spectrum anti-coronavirus agent

Curcumin released from magnetic hydrogels promotes the secretion of vascular endothelial growth factor

Cryo-EM imaging of a key immune protein reveals previously unrecognized binding site

Developing and manufacturing custom recombinant antibodies for R&D

Sodium thiosulfate shows no benefits for reducing heart damage following a heart attack

Advancing therapeutic biopolymer development eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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