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Iron retention in skin linked to psoriasis: Could hepcidin be the missing piece in treatment?

This study reveals hepcidin's significant role in psoriasis, linking iron retention to inflammation and keratinocyte growth, suggesting new therapeutic targets.

1 Oct 2024

Traditional Chinese medicine shows potential in cancer treatment

Cancer, a pervasive global health concern, remains a leading cause of mortality worldwide. Current cancer treatment modalities encompass surgery, radiotherapy, chemotherapy, immunotherapy, and targeted therapy, all of which have significantly contributed to improving patient survival.

1 Oct 2024

Study finds microplastics in semen and urine, linking PTFE exposure to lower sperm count

Researchers in China found multiple types of microplastics in human semen and urine, with exposure to PTFE significantly linked to reduced sperm quality, highlighting potential reproductive health risks.

1 Oct 2024

New treatment strategy targets somatostatin to prevent blood sugar drops in type 1 diabetes

Inhibiting the hormone somatostatin may be a new treatment strategy to prevent dangerous blood glucose drops in type 1 diabetes.

30 Sep 2024

Regulating iron overload: Liraglutide's potential benefits

Researchers assess the role of liraglutide in regulating iron metabolism in a mouse model of hereditary hemochromatosis.

30 Sep 2024

The consumption of flavonoid-rich foods was associated with a reduced risk of NAFLD among middle-aged adults

Research indicates that high flavonoid intake is linked to a lower risk of NAFLD, with apples and tea showing significant protective effects on liver health.

30 Sep 2024

Study uncovers biological drivers of plasma proteins, offering new insights for disease biomarkers and drug discovery

Researchers mapped the biological influences on 4,775 plasma proteins, revealing the interplay of modifiable and non-modifiable factors, with key implications for disease biomarkers and drug targets.

30 Sep 2024

Glutathione found to significantly reduce acetaldehyde levels and help relieve hangovers

Study demonstrates that glutathione (GSH) significantly reduces acetaldehyde levels, a key factor in hangovers, though subjective symptoms showed little difference between groups. Pharmacokinetic data indicate that GSH accelerates acetaldehyde clearance, providing potential relief from hangover symptoms.

29 Sep 2024

Estrogen found to promote tumor growth in breast cancers without receptors

Estrogens are known to drive tumor growth in breast cancer cells that carry its receptors, but a new study by Duke Cancer Institute researchers unexpectedly finds that estrogens play a role in fueling the growth of breast cancers without the receptors, as well as numerous other cancers.

27 Sep 2024

Why hypoglycemia-induced glucagon secretion becomes impaired in diabetes

Findings indicate that excessive somatostatin inhibits glucagon secretion in type 1 diabetes, offering a novel target for hypoglycemia management strategies.

27 Sep 2024

12-week coffee compound study shows promising results for weight and fat reduction in at-risk individuals

Cafestol may aid in reducing body weight and visceral fat, but its impact on insulin sensitivity and glucose tolerance remains limited, according to the study.

27 Sep 2024

Liver receptor mutations linked to liver dysfunction, cholesterol accumulation, and hepatitis

Damaging LXRα variants are linked to liver cholesterol buildup and hepatitis, emphasizing the receptor's importance in cholesterol sensing and liver function.

27 Sep 2024

Hormone hepcidin identified as potential trigger for psoriasis

Scientists may have uncovered the root cause of psoriasis, a chronic and sometimes debilitating skin disease that affects 2-3% of the global population. The condition is characterized by red, scaly patches that impact the quality of a patient's life and can sometimes be life-threatening.

26 Sep 2024

Global surge in childhood obesity signals an urgent health crisis

Since 1990, the rise in childhood overweight and obesity has surged across every continent, almost doubling in prevalence. While the United States has the highest prevalence, other nations are not far behind.

26 Sep 2024

Why children with Down’s syndrome are predisposed to developing leukaemia

The study uncovers mechanisms linking Down syndrome to leukemia, emphasizing the role of oxidative stress and genetic alterations in fetal blood development.

26 Sep 2024

Understanding the role of TIPS in improving renal function amid cirrhosis

Cirrhosis is one of the leading causes of mortality from non-communicable diseases, with complications arising as liver function deteriorates.

26 Sep 2024

Barcoding technology reveals secrets of cancer metastasis

Metastatic cancer can be a devastating diagnosis. The cancer is spreading. It may travel to multiple organs in the body. This could mean more pain and ultimately, death.

26 Sep 2024

New pipeline of drug candidates offers hope for effective MASLD treatments

Non-alcoholic fatty liver disease (NAFLD), recently reclassified as metabolic dysfunction-associated steatotic liver disease (MASLD), has become the most prevalent chronic liver disease globally.

25 Sep 2024

Study reveals life-changing impact of gene therapy for hemophilia B patients

Adults with hemophilia B saw their number of bleeding episodes drop by an average of 71 percent after a single infusion of gene therapy, according to the results of an international Phase III clinical trial published today in the New England Journal of Medicine by researchers from the University of Pennsylvania Perelman School of Medicine and a multicenter group of investigators.

25 Sep 2024

Study sheds light on mechanisms behind liver fibrosis and potential therapies

New research from the University of Pittsburgh School of Pharmacy sheds light on the processes that lead to liver fibrosis and suggests a novel treatment approach for this common and serious condition.

25 Sep 2024

Liver News and Research

Iron retention in skin linked to psoriasis: Could hepcidin be the missing piece in treatment?

Traditional Chinese medicine shows potential in cancer treatment

Study finds microplastics in semen and urine, linking PTFE exposure to lower sperm count

New treatment strategy targets somatostatin to prevent blood sugar drops in type 1 diabetes

Regulating iron overload: Liraglutide's potential benefits

The consumption of flavonoid-rich foods was associated with a reduced risk of NAFLD among middle-aged adults

Study uncovers biological drivers of plasma proteins, offering new insights for disease biomarkers and drug discovery

Glutathione found to significantly reduce acetaldehyde levels and help relieve hangovers

Estrogen found to promote tumor growth in breast cancers without receptors

Why hypoglycemia-induced glucagon secretion becomes impaired in diabetes

12-week coffee compound study shows promising results for weight and fat reduction in at-risk individuals

Liver receptor mutations linked to liver dysfunction, cholesterol accumulation, and hepatitis

Hormone hepcidin identified as potential trigger for psoriasis

Global surge in childhood obesity signals an urgent health crisis

Why children with Down’s syndrome are predisposed to developing leukaemia

Understanding the role of TIPS in improving renal function amid cirrhosis

Barcoding technology reveals secrets of cancer metastasis

New pipeline of drug candidates offers hope for effective MASLD treatments

Study reveals life-changing impact of gene therapy for hemophilia B patients

Study sheds light on mechanisms behind liver fibrosis and potential therapies

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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