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Amorphous calcium phosphate drives aortic valve stiffening

The human body has sophisticated defenses against the deposition of calcium minerals that stiffen heart tissues, researchers at the University of Illinois Urbana-Champaign and collaborators at UCLA Health and the University of Texas at Austin found in a new study that provides the first detailed, step-by-step documentation of how calcification progresses.

27 Jun 2024

Experts call for better information and treatments for post-orgasmic illness syndrome

A study in the "International Journal of Impotence Research" reveals that sexual medicine experts find current information on post-orgasmic illness syndrome (POIS) inadequate, often referring patients for psychotherapy or prescribing antihistamines with limited symptom improvement.

26 Jun 2024

Moderate physical activity may be linked to reduced risk of ALS later in life

Moderate levels of physical activity and fitness may be linked to a reduced risk of amyotrophic lateral sclerosis (ALS) later in life, according to a new study published in the June 26, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

26 Jun 2024

Comparative study on preventative SMA therapies shows mixed outcomes

In a first-of-its-kind study, researchers compared the efficacy of preventative therapy for spinal muscular atrophy (SMA) between two well-matched study groups, using either gene therapy (onasemnogene abeparvovec) alone or in combination with risdiplam (oral medication) or nusinersen (intrathecal injection) administered before apparent signs of disease emerged.

25 Jun 2024

Beyond genes, new research explores mechanics and calcium signaling

Using animals to study heart disease doesn't always translate well to human health outcomes, and human heart cells available for research don't work outside the human body.

25 Jun 2024

KU researchers uncover role of Src gene in nervous system development

Many people are familiar with oncogenes - genes long known to be involved in cancers in humans, such as the gene "Src."

24 Jun 2024

Researchers debunk four common myths about the safety of intermittent fasting

In a new article, researchers at the University of Illinois Chicago debunk four common myths about the safety of intermittent fasting.

24 Jun 2024

12 months of heavy resistance training around retirement may have long-lasting benefits

Researchers investigated the long-term effects of varying intensities of supervised resistance training in retirement-age adults.

24 Jun 2024

Mindfulness meditation curbs gaming addiction by altering brain responses

Mindfulness meditation significantly reduces gaming cravings and addiction severity in adults with Internet Gaming Disorder. The study reveals decreased activation in brain regions associated with craving, such as the lentiform nuclei and medial frontal gyrus.

23 Jun 2024

Integrated cellular map of heart cells unlocks cardiac fibrosis process

Scientists at the Victor Chang Cardiac Research Institute in Australia have produced a first of its kind integrated map of heart cells which unlocks the process of cardiac fibrosis – a major cause of heart failure.

21 Jun 2024

Restoring youthful TERT levels reverses aging phenotypes in preclinical models

Researchers at The University of Texas MD Anderson Cancer Center have demonstrated that therapeutically restoring 'youthful' levels of a specific subunit of the telomerase enzyme can significantly reduce the signs and symptoms of aging in preclinical models.

21 Jun 2024

Can nuts boost weight loss and blood sugar control on a calorie-restricted diet?

Researchers compared the effects of energy-restricted (ER) dietary patterns with nuts or without on body composition, weight, and glycemic management.

21 Jun 2024

Innovative CAR T cell therapy shows promise for relapsed CIDP patients

This study is led by Professor Junnian Zheng and Ming Shi from the Cancer Institute of Xuzhou Medical University, together with the team of Professor Guiyun Cui and Wei Zhang from the Affiliated Hospital of Xuzhou Medical University.

20 Jun 2024

Exercising at night improves glucose control in overweight adults

Researchers explore differences in the timing physical activity and its impact on blood glucose levels and metabolic function.

20 Jun 2024

Study shows effects of year-long heavy resistance training on vital leg strength

Twelve months of heavy resistance training - exercise that makes muscles work against a force - around retirement preserves vital leg strength years later, show the follow up results of a clinical trial, published online in the open access journal BMJ Open Sport & Exercise Medicine.

19 Jun 2024

Researchers propose a 'protein aggregation clock' to measure aging and health

Could measuring protein clumps in our cells be a new way to find out our risk of getting age-related diseases? Professor Dorothee Dormann and Professor Edward Lemke of Johannes Gutenberg University Mainz (JGU), who are also adjunct directors at the Institute of Molecular Biology (IMB) in Mainz, propose the concept of a "protein aggregation clock" to measure ageing and health in a new perspective article published in Nature Cell Biology.

19 Jun 2024

Discovery of mobile regulatory T cells could revolutionize disease treatment

Scientists at the University of Cambridge have discovered that a type of white blood cell - called a regulatory T cell - exists as a single large population of cells that constantly move throughout the body looking for, and repairing, damaged tissue.

18 Jun 2024

Nicotinamide riboside boosts walking endurance in peripheral artery disease

The over-the-counter supplement nicotinamide riboside, a form of vitamin B3, increased the walking endurance of patients with peripheral artery disease, a chronic leg condition for which there are few effective treatments.

18 Jun 2024

Study: Hepatitis E virus may be both sexually transmitted and linked to male infertility

Discovering that hepatitis E virus is associated with sperm in pigs suggests the virus may be both sexually transmitted and linked to male infertility, according to a new study.

18 Jun 2024

Blood test identifies specific pathologies in frontotemporal dementia, ALS, and PSP

In a study with 991 adults, scientists at DZNE show that the most common forms of frontotemporal dementia (FTD) as well as the neurological diseases amyotrophic lateral sclerosis (ALS) and progressive supranuclear palsy (PSP) can be recognized by blood testing.

18 Jun 2024