Physiology News and Research

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Human physiology is the science of the mechanical, physical, and biochemical functions of humans in good health, their organs, and the cells of which they are composed. The principal level of focus of physiology is at the level of organs and systems. Most aspects of human physiology are closely homologous to corresponding aspects of animal physiology, and animal experimentation has provided much of the foundation of physiological knowledge. Anatomy and physiology are closely related fields of study: anatomy, the study of form, and physiology, the study of function, are intrinsically tied and are studied in tandem as part of a medical curriculum.

Hyperinsulinemic patients with breast cancer may be responsive to metabolism-targeting treatments

Scientists at Yale Cancer Center have found that patients with breast cancer and high levels of insulin in the blood may be responsive to metabolism-targeting treatments, which in turn may improve the effectiveness of subsequent chemotherapy treatments.

20 May 2022

Study demonstrates how the transcription factor C/EBPβ can positively influence fat storage

The chronic nutritional and metabolic disease of obesity is characterized by an excessive increase in body fat and its accumulation in tissues.

20 May 2022

New insights on avian influenza spillover and global spread

When it comes to avian influenza, more commonly known as bird flu, all birds are not created equal.

19 May 2022

Associations between mucosal gene expression and microbiome composition in three gastrointestinal disorders

A new study authored by Sambhawa Priya and other researchers offers a detailed look at the interactions between the gut microbiome of humans in health and disease.

19 May 2022

Origin, evolution and ecological relationships of yeasts

Yeasts have been evolving and diversifying for more than 400 million years. Likely, symbiotic relationships between humans and yeasts started already at the origin of our species (200-300 thousand years ago).

17 May 2022

Exposure to cold and warm temperatures causes changes in gene expression in various organs

Human beings, like most organisms, are constantly exposed to alternating colder or warmer temperatures.

17 May 2022

Mice live longer with nasal gene therapy

In a recent study published in the Proceedings of the National Academy of Sciences journal, researchers assessed the efficiency of a novel intranasal and injectable therapy in improving life expectancy.

17 May 2022

Tabula sapiens, most comprehensive human cell atlas

In a recent study published in the journal Science, researchers created an atlas termed the Tabula sapiens for over 400 distinct cell types of humans. Several aspects of human physiology were revealed by the atlas, such as how different types of cells splice genes differently.

16 May 2022

Exercise increases levels of brain-derived neurotrophic factor which bolsters dopamine release

Exercise increases levels of a chemical involved in brain cell growth, which bolsters the release of the "feel good" hormone dopamine, a new study shows. Dopamine is known to play a key role in movement, motivation, and learning.

16 May 2022

New model provides a deep physiology-based explanation of how deep brain stimulation works

People with Parkinson's disease and their doctors confront many unknowns, including the answer to exactly how deep brain stimulation (DBS) relieves some of the motor symptoms patients experience.

16 May 2022

New mouse model shows the connection between stress, depression and cardiovascular disease risk

Results from a new mouse model may aid in understanding how depression and prolonged and severe stress increase the risk of cardiovascular disease, according to preliminary research presented at the American Heart Association's Vascular Discovery: From Genes to Medicine Scientific Sessions 2022.

13 May 2022

Maternal obesity greatly increases offspring's risk of cardiac problems in later life

Maternal obesity impairs heart health and function of the fetus according to a new study in mice. The study, published in The Journal of Physiology found that maternal obesity causes molecular changes in the heart of the fetus and alters expression of genes related to nutrient metabolism, which greatly increases offspring's risk of cardiac problems in later life.

12 May 2022

Rutgers study identifies key protein for brain stem cell longevity

A receptor that was first identified as necessary for insulin action, that also is located on the neural stem cells found deep in the brains of mice, is pivotal for brain stem cell longevity, according to a Rutgers study, a finding that has important implications for brain health and future therapies for brain disorders.

11 May 2022

New methods can make spinal cord less excitable and could be used to treat muscle spasms

Poor sleep, difficulty moving and injuries from hitting something accidentally are just some of the challenges faced by suffers of often-painful involuntary muscle spasms.

11 May 2022

COVID-19 and cerebral blood flow

In a recent study posted to the medRxiv* preprint server, researchers assessed the impact of coronavirus disease 2019 (COVID-19) on cerebral blood flow in infected patients.

10 May 2022

Exploring the impact of bacterial infection and gut microbiome on colorectal cancer development

Intestinal micro-biodiversity is important for maintaining colorectal and general health. Imbalance in this microenvironment can result in chronic infections, even cancer.

10 May 2022

Cancer cells in an acidic environment undergo lipid synthesis and accumulation, study shows

Alterations in metabolic processes are a hallmark of cancer and can lead to a tumor environment that is acidic. As a result, cancer cells must adapt to survive in this inhospitable environment.

10 May 2022

Postnatal gene therapy may be able to prevent or reverse deadly effects of Pitt-Hopkins syndrome

UNC School of Medicine Scientists have shown for the first time that postnatal gene therapy may be able to prevent or reverse many deleterious effects of a rare genetic disorder called Pitt-Hopkins syndrome.

10 May 2022

Study offers insight into seasonality of children’s growth and weight gain

It has been long recognized that in Western countries, children are more likely to become overweight or obese over the summer.

10 May 2022

Gene therapy effectively reduces neuropathic pain in mice with spinal cord injuries

An international team of researchers, led by scientists at University of California San Diego School of Medicine, report that a gene therapy that inhibits targeted nerve cell signaling effectively reduced neuropathic pain with no detectable side effects in mice with spinal cord or peripheral nerve injuries.

9 May 2022

Physiology News and Research

Hyperinsulinemic patients with breast cancer may be responsive to metabolism-targeting treatments

Study demonstrates how the transcription factor C/EBPβ can positively influence fat storage

New insights on avian influenza spillover and global spread

Associations between mucosal gene expression and microbiome composition in three gastrointestinal disorders

Origin, evolution and ecological relationships of yeasts

Exposure to cold and warm temperatures causes changes in gene expression in various organs

Mice live longer with nasal gene therapy

Tabula sapiens, most comprehensive human cell atlas

Exercise increases levels of brain-derived neurotrophic factor which bolsters dopamine release

New model provides a deep physiology-based explanation of how deep brain stimulation works

New mouse model shows the connection between stress, depression and cardiovascular disease risk

Maternal obesity greatly increases offspring's risk of cardiac problems in later life

Rutgers study identifies key protein for brain stem cell longevity

New methods can make spinal cord less excitable and could be used to treat muscle spasms

COVID-19 and cerebral blood flow

Exploring the impact of bacterial infection and gut microbiome on colorectal cancer development

Cancer cells in an acidic environment undergo lipid synthesis and accumulation, study shows

Postnatal gene therapy may be able to prevent or reverse deadly effects of Pitt-Hopkins syndrome

Study offers insight into seasonality of children’s growth and weight gain

Gene therapy effectively reduces neuropathic pain in mice with spinal cord injuries

Industry Focus eBook - Cell biology (5th edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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