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Study unravels new mechanism for muscle repair after physiological damage

Muscle is known to regenerate through a complex process that involves several steps and relies on stem cells. Now, a new study led by researchers at Pompeu Fabra University (UPF, Spain)/Centro Nacional de Investigationes Cardiovasculares (CNIC, Spain)/CIBERNED (Spain) and Instituto de Medicina Molecular João Lobo Antunes (iMM, Portugal), published on 15 October in the journal Science, describes a new mechanism for muscle repair after physiological damage relying on the rearrangement of muscle fiber nuclei, and independently of muscle stem cells.

15 Oct 2021

UQ research center aims to reduce the number of stillbirths

More than 2,100 babies are stillborn in Australia every year – a statistic that hasn't changed in nearly 30 years.

14 Oct 2021

Study reveals the zoonotic potential of the rat Sialodacryoadenitis virus

A new review aimed to describe the current state of knowledge on Sialodacryoadenitis virus, along with its characteristics and potential zoonotic threat.

13 Oct 2021

Penn Medicine and Siemens Healthineers provide free breast cancer screenings for underserved women

As part of Breast Cancer Awareness Month, Penn Medicine will be providing free breast cancer screenings, no insurance required, to women in need over the age of 40.

13 Oct 2021

Research reveals components of Sinbis virus ribonucleoproteins

To address this gap in research regarding the understanding of post-replicative alphavirus RNPs, scientists have created a novel proteome-wide approach known as viral RNA interactome capture (vRIC). This study is available in the bioRxiv* preprint server while awaiting peer review.

11 Oct 2021

Mortality among people with mental health conditions amplified during the COVID-19 pandemic

The greater number of deaths amongst those with mental health conditions and intellectual disabilities has been amplified during the COVID-19 pandemic, a study based on more than 160,000 patients has revealed.

11 Oct 2021

Characterization of circulating neutrophils from hospitalized COVID-19 patients

A new preprint deals with the characterization of neutrophil phenotypes in an attempt to provide biomarkers that can predict severe disease in patients hospitalized with COVID-19.

8 Oct 2021

Scientists identify a new method to treat triple-negative breast cancer

A team of clinicians and scientists from the National Cancer Centre Singapore (NCCS), Singapore General Hospital (SGH) and A*STAR's Genome Institute of Singapore (GIS) has identified a novel method to treat triple-negative breast cancer (TNBC). They discovered that cancer cells switch between different cell states and are able to change from being less aggressive ('epithelial') to being more aggressive ('mesenchymal'), and vice versa.

7 Oct 2021

New low-cost ventilator could address the shortage of ventilators in developing countries

A new low-cost ventilator design invented during COVID-19 could address the global shortage of ventilators for other respiratory diseases.

5 Oct 2021

Study investigates long-COVID symptoms in people recovering from COVID-19 infection

This new study from the University of Oxford and the National Institute for Health Research (NIHR) Oxford Health Biomedical Research Centre (BRC) investigated long-COVID in over 270,000 people recovering from COVID-19 infection, using data from the US-based TriNetX electronic health record network.

30 Sep 2021

Researchers supplement synthetic biology toolkit to streamline investigations into genetic code expansion

One of modern biologists' most ambitious goals is to learn how to expand or otherwise modify the genetic code of life on Earth, in order to make new, artificial life forms.

30 Sep 2021

New 'priming' approach may improve the efficacy of chemotherapy for pancreatic cancer

A new approach to 'prime' the tumor environment may improve how effective chemotherapy is for pancreatic ductal adenocarcinoma, one of the most aggressive forms of pancreatic cancer.

29 Sep 2021

Researchers develop efficient approach to identify 3D features of post-infarction scarring

A multidisciplinary team of scientists based at the Universidad de Valladolid and the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has developed a highly efficient method for identifying the 3-dimensional features of the scar tissue formed after a myocardial infarction.

28 Sep 2021

Researchers describe a novel role for hnRNP E1 protein in binding DNA in the nucleus

Cancer is a devastating disease and is the second leading cause of death in the U.S. One of the hallmarks of cancer is genomic instability, or the tendency to accumulate mutations and damage to the DNA that leads to genome alterations during cell division.

25 Sep 2021

Small molecule drug can attenuate the triggers of neuroinflammation, preclinical study shows

Neuroinflammation can worsen outcomes in stroke, traumatic brain injury, or spinal cord injury, as well as accelerate neurodegenerative diseases like ALS, Parkinson's, or Alzheimer's. This suggests that limiting neuroinflammation may represent a promising new approach to treat neurological diseases and neuropathic pain that are driven by neuroinflammation.

24 Sep 2021

Design of mRNA vaccines to combat COVID-19

A recent review study discusses fundamental concepts in the successful delivery of nucleic acids in therapeutics.

23 Sep 2021

New discovery offers clues to overcoming resistance to cancer therapies

Cancer cells proliferate despite a myriad of stresses - from oxygen deprivation to chemotherapy - that would kill any ordinary cell.

23 Sep 2021

Varying immune responses after single dose of Pfizer and AstraZeneca COVID-19 vaccines

A new preprint describes the significant variation in the early immune response elicited by two of the earliest vaccines to gain emergency authorization against COVID-19.

23 Sep 2021

Discovery points toward a new strategy for treating Parkinson's disease

University of Utah Health scientists have identified a molecule that slows cells' production of alpha-synuclein, a protein that forms toxic aggregates in the brains of people with Parkinson's disease.

23 Sep 2021

Researchers apply deep learning to PS-OCT systems to better detect cancer

Yi "Edwin" Sun, a Ph.D. candidate in electrical and computer engineering at the University of Illinois Urbana-Champaign and member of the Beckman Institute's Biophotonics Imaging Laboratory headed by Stephen Boppart, explored how deep learning methods can make polarization-sensitive optical coherence tomography, or PS-OCT, more cost-effective and better equipped to diagnose cancer in biological tissues.

23 Sep 2021

Translation News and Research

Study unravels new mechanism for muscle repair after physiological damage

UQ research center aims to reduce the number of stillbirths

Study reveals the zoonotic potential of the rat Sialodacryoadenitis virus

Penn Medicine and Siemens Healthineers provide free breast cancer screenings for underserved women

Research reveals components of Sinbis virus ribonucleoproteins

Mortality among people with mental health conditions amplified during the COVID-19 pandemic

Characterization of circulating neutrophils from hospitalized COVID-19 patients

Scientists identify a new method to treat triple-negative breast cancer

New low-cost ventilator could address the shortage of ventilators in developing countries

Study investigates long-COVID symptoms in people recovering from COVID-19 infection

Researchers supplement synthetic biology toolkit to streamline investigations into genetic code expansion

New 'priming' approach may improve the efficacy of chemotherapy for pancreatic cancer

Researchers develop efficient approach to identify 3D features of post-infarction scarring

Researchers describe a novel role for hnRNP E1 protein in binding DNA in the nucleus

Small molecule drug can attenuate the triggers of neuroinflammation, preclinical study shows

Design of mRNA vaccines to combat COVID-19

New discovery offers clues to overcoming resistance to cancer therapies

Varying immune responses after single dose of Pfizer and AstraZeneca COVID-19 vaccines

Discovery points toward a new strategy for treating Parkinson's disease

Researchers apply deep learning to PS-OCT systems to better detect cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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