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Researchers characterize new SARS-CoV-2 BA.2.86 variant neutralization by monoclonal antibodies

Researchers used a SARS-CoV-2 spike protein-pseudotyped viral model to characterize BA.2.86 variant neutralization by monoclonal antibodies.

6 Sep 2023

Early viral exposure in mice weakens vaccine response, raising questions for human studies

Researchers at Washington University have demonstrated that early life exposure to multiple viruses in house mice dampens the immune response to SARS-CoV-2 vaccinations later in life. The study raises concerns about the applicability of common mouse models in immunological research, suggesting that prior pathogen exposure could be a significant variable in predicting vaccine efficacy.

5 Sep 2023

Novavax's updated XBB.1.5 vaccine shows promising cross-neutralizing antibodies against new COVID-19 variants

The study reveals that Novavax's updated XBB.1.5 vaccine effectively induces cross-neutralizing antibodies against multiple Omicron XBB sub-variants in both mice and non-human primates.

5 Sep 2023

Can SARS-CoV-2 infect poultry?

New research in the Virology Journal suggests that chickens could become intermediate hosts for newly emerged SARS-CoV-2 variants, posing a potential threat to public health. The study identifies AXL and ACE2 receptors in chickens as likely binding sites for the virus, highlighting the need for further research and preventive measures.

5 Sep 2023

Diet sodas trick your saliva: Study reveals how sweetened drinks impact oral enzymes and insulin levels

The study investigates the effects of sweetened beverages on salivary insulin, aspartame, and alpha-amylase levels in healthy young adults. It found that diet soft drinks led to higher salivary aspartame and insulin levels compared to sweetened water, raising questions about artificial sweeteners' impact on metabolic processes.

5 Sep 2023

Targeting the ORAI1 calcium channel could provide new approach to treating oral cancer

An essential protein that acts as a gatekeeper for calcium entering cells promotes the growth of oral cancer and generates pain, according to a new study published in Science Signaling led by researchers at NYU College of Dentistry.

5 Sep 2023

Experts call for changes to how drugs are tested and labeled for people with obesity

A new opinion piece published in Health Affairs Forefront raises questions around current approaches to assess drug safety and effectiveness in people with obesity.

5 Sep 2023

SARS-CoV-2 Eris variant spreads faster and dodges immunity

Study investigates the characteristics of the EG.5.1 "Eris" variant of SARS-CoV-2, finding it more transmissible among hamsters and slightly better at evading immunity compared to the XBB.1.5 variant. The results suggest that these properties could be driving the variant's increasing prevalence in human populations.

5 Sep 2023

New blood test pinpoints Parkinson's disease through mitochondrial DNA damage

Researchers have developed a new blood test that measures mitochondrial DNA damage as a potential marker for Parkinson's disease (PD). The study shows the test could aid in diagnosing PD and assessing responses to LRRK2 kinase inhibitors, which may help in reducing mitochondrial damage in PD patients.

4 Sep 2023

Study investigates the pathophysiological mechanisms of PASC after COVID-19

Researchers investigated early pathophysiological mechanisms potentially underlying PASC post-SARS-CoV-2 infection.

4 Sep 2023

Study reports highly pathogenic avian influenza A infection in pet dogs and cat on a rural poultry farm in Italy

Researchers presented serological evidence of highly pathogenic avian influenza (HPAI) H5N1 virus infection in a pet cat and five dogs on a rural poultry farm in Italy.

4 Sep 2023

The first point-of-care genetic test for lactose intolerance: A compact, lab-on-phone diagnostic assay

The performance of a compact diagnostic assay that can accurately and rapidly diagnose lactose intolerance.

4 Sep 2023

Machine learning helps identify metabolic biomarkers that could predict cancer risk

A novel study from the University of South Australia has identified a range of metabolic biomarkers that could help predict the risk of cancer.

4 Sep 2023

Intensive fasting boosts red blood cells' immune powers against COVID-19, study finds

Researchers found that short-term intensive fasting enhances the immune function of red blood cells, including their ability to combat SARS-CoV-2, without affecting their oxygen-carrying capacity. The study reveals that this fasting regimen popular in Asia could offer a multifaceted benefit by amplifying the body's defenses without compromising essential functions.

4 Sep 2023

IBS researchers discover new insights into the regulation of fat metabolism

This is a significant development that brings hope to the one billion individuals with obesity worldwide. Researchers led by Director C. Justin LEE from the Center for Cognition and Sociality (CCS) within the Institute for Basic Science (IBS) have discovered new insights into the regulation of fat metabolism.

31 Aug 2023

Boosters slow antibody waning but hit a ceiling: Long-term COVID study reveals limits of immunity

The study tracks the long-term kinetics of antibody responses to SARS-CoV-2 after vaccination and infections in New York healthcare workers from 2020 to 2023. It reveals that antibody waning is slower after booster shots, but there's an upper limit to antibody levels, which gradually lowers with repeated SARS-CoV-2 exposures and vaccinations.

31 Aug 2023

Study reveals pathogenic mechanism of rare pediatric neurodegenerative disorder

A recent study published in Nature Metabolism has revealed the pathogenic mechanism underlying a rare pediatric neurodegenerative disorder known as mitochondrial enoyl reductase protein-associated neurodegeneration (MEPAN) syndrome.

31 Aug 2023

Scientists discover new microglial population important for memory and learning

Following more than seven years of research, researchers at the University of Seville-IBiS (Institute of Biomedicine of Seville) have identified a new key cell type with a critical role in the developmental processes of memory and learning.

31 Aug 2023

Researchers unearth secrets of zinc transporter protein

A group of researchers has unearthed the secrets behind a tiny but crucial protein that shuttles zinc ions (Zn2+) within our bodies. The discovery offers a deeper understanding of how our cells maintain optimal health.

31 Aug 2023

New omicron variants can reinfect people who were infected with earlier variants

The omicron variants of the SARS-CoV-2 virus, which have rapidly spread around the world over the past year, latch onto our cells more tightly, invade them more efficiently, and elude many of the antibodies induced by previous infections and vaccines.

30 Aug 2023

Enzyme News and Research

Researchers characterize new SARS-CoV-2 BA.2.86 variant neutralization by monoclonal antibodies

Early viral exposure in mice weakens vaccine response, raising questions for human studies

Novavax's updated XBB.1.5 vaccine shows promising cross-neutralizing antibodies against new COVID-19 variants

Can SARS-CoV-2 infect poultry?

Diet sodas trick your saliva: Study reveals how sweetened drinks impact oral enzymes and insulin levels

Targeting the ORAI1 calcium channel could provide new approach to treating oral cancer

Experts call for changes to how drugs are tested and labeled for people with obesity

SARS-CoV-2 Eris variant spreads faster and dodges immunity

New blood test pinpoints Parkinson's disease through mitochondrial DNA damage

Study investigates the pathophysiological mechanisms of PASC after COVID-19

Study reports highly pathogenic avian influenza A infection in pet dogs and cat on a rural poultry farm in Italy

The first point-of-care genetic test for lactose intolerance: A compact, lab-on-phone diagnostic assay

Machine learning helps identify metabolic biomarkers that could predict cancer risk

Intensive fasting boosts red blood cells' immune powers against COVID-19, study finds

IBS researchers discover new insights into the regulation of fat metabolism

Boosters slow antibody waning but hit a ceiling: Long-term COVID study reveals limits of immunity

Study reveals pathogenic mechanism of rare pediatric neurodegenerative disorder

Scientists discover new microglial population important for memory and learning

Researchers unearth secrets of zinc transporter protein

New omicron variants can reinfect people who were infected with earlier variants

Understanding the DNA Damage Response in Innate Immunity eBook

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