Gastroenterology News and Research

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Gastroenterology is the branch of medicine where the digestive system and its disorders are studied.

International commission calls for action against hepatocellular carcinoma

Liver cancer is the sixth most common cancer as well as the third highest cause of cancer-related mortality worldwide.

8 Aug 2025

Updated multidisciplinary European guidelines redefine MASLD diagnosis and treatment

The 2024 European clinical practice guidelines introduce a pivotal terminology shift, replacing NAFLD (non-alcoholic fatty liver disease) with MASLD (metabolic dysfunction-associated steatotic liver disease) and NASH with MASH (metabolic dysfunction-associated steatohepatitis).

7 Aug 2025

Survey reveals persistent challenges of IBS on daily life and productivity

Despite social media helping to increase awareness of irritable bowel syndrome (IBS) among the public (81% of health care providers agree) and advancements in treatment over the past decade, IBS symptoms continue to significantly impact patients' daily lives and productivity, according to a new survey released by the American Gastroenterological Association (AGA), in partnership with The Harris Poll, a Stagwell (STGW) agency.

7 Aug 2025

Mouth and gut microbes talk to each other - here’s why it matters for disease

Researchers reviewed nearly 250 studies to uncover how the oral and gut microbiomes communicate through multiple pathways, influencing the risk of diseases such as IBD, colorectal cancer, and cardiovascular disorders. The review highlights that maintaining oral health and dietary habits is crucial for overall systemic wellbeing.

4 Aug 2025

Low FODMAP diet found to repair leaky gut in IBS-D patients

In a study, patients with irritable bowel syndrome with diarrhea, or IBS-D, who went on a low FODMAP diet saw an improvement of colonic barrier dysfunction, commonly known as "leaky gut."

30 Jul 2025

Study identifies risk factors for second colorectal cancer in people with Lynch syndrome

A current study by the German Familial Colorectal Cancer Consortium is looking at the question of which people with Lynch syndrome are at an increased risk of developing a second colorectal cancer.

30 Jul 2025

Study confirms post-pandemic rise in disorders of gut-brain interaction

A new international study confirmed a significant post-pandemic rise in disorders of gut-brain interaction, including irritable bowel syndrome (IBS) and functional dyspepsia, according to the paper published in Clinical Gastroenterology and Hepatology.

30 Jul 2025

Blood-based tests show promise for colorectal cancer screening but follow-up challenges persist

A study led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center found that while blood-based tests offer a more convenient option for colorectal cancer screening, only 49% of patients completed a follow-up colonoscopy within six months, and just 56% did so at any point during the two-year study period.

29 Jul 2025

The Mount Sinai Hospital named among nation’s top 20 for care excellence

The Mount Sinai Hospital, the flagship hospital of Mount Sinai Health System, was listed among the nation's top 20 hospitals for care excellence by U.S. News & World Report for 2025-26, marking the 10th consecutive year the hospital has been listed on the publication's "Honor Roll."

29 Jul 2025

Rising liver cancer rates highlight need for urgent action worldwide

The majority of liver cancer cases could be prevented by reducing levels of viral hepatitis, alcohol consumption and MASLD (metabolic dysfunction-associated steatotic liver disease – previously called non-alcoholic fatty liver disease), suggests an analysis as part of The Lancet Commission on liver cancer.

29 Jul 2025

Study reveals stigmatizing responses in LLMs for addiction-related queries

As artificial intelligence is rapidly developing and becoming a growing presence in healthcare communication, a new study addresses a concern that large language models (LLMs) can reinforce harmful stereotypes by using stigmatizing language.

26 Jul 2025

AI tool helps doctors predict hospital death risk in cirrhosis patients

Predicting who might die while in the hospital is one of the hardest challenges for doctors caring for people with serious liver disease.

24 Jul 2025

Heavy drinking now poses greater liver disease risk than two decades ago

Americans who drink heavily are more than twice as likely to develop significant liver disease compared to 20 years ago, according to a new Keck Medicine of USC study published today in Clinical Gastroenterology and Hepatology.

23 Jul 2025

Machine learning improves prediction of death risk in hospitalized cirrhosis patients

Researchers employed a machine learning technique known as random forest analysis and found that it significantly outperformed traditional methods in predicting which hospitalized patients with cirrhosis are at risk of death, according to a new paper published in Gastroenterology.

23 Jul 2025

Restricted diet triggers drop in microbial diversity without convergence

According to a recent exploratory study published in eGastroenterology, the answer is more complex than expected. Researchers from KU Leuven and collaborating institutions conducted a tightly controlled dietary intervention, known as the "Oatmeal Study", to examine whether restricting food variety could induce convergence in the gut microbiota across individuals.

22 Jul 2025

Gluten may not be the culprit for many people with irritable bowel syndrome

A new study from McMaster University researchers has found that many people with irritable bowel syndrome (IBS) who believe they are sensitive to gluten or wheat may not actually react to these ingredients.

22 Jul 2025

ANXA2 positive hepatocytes drive migration based repair in acute liver failure

Acute liver failure (ALF) represents a life-threatening condition marked by rapid deterioration of liver function, often necessitating urgent liver transplantation.

18 Jul 2025

Study reveals complex patterns of burden and survival among people with digestive system cancers in China

Digestive system malignancies (DSMTs)-including esophageal, gastric, colorectal, liver, and pancreatic cancers-represent a major public health challenge in China.

18 Jul 2025

Research highlights guselkumab's impact on Crohn's endoscopic healing

In a major advance for patients with Crohn's disease, a new study led by researchers at Mount Sinai Health System found that guselkumab, a medication with a mechanism of action that is new to inflammatory bowel disease (IBD) treatment, outperformed an established standard of care in promoting intestinal healing and symptom relief.

18 Jul 2025