Hippocampus News and Research

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The hippocampus is a part of the forebrain, located in the medial temporal lobe. It belongs to the limbic system and plays major roles in short term memory and spatial navigation. Humans and other mammals have two hippocampi, one in each side of the brain.

Socially enriched environments linked to better memory and cognitive flexibility in aged rats

A new research paper was published in Volume 17, Issue 9 of Aging-US on August 22, 2025, titled, "The impact of long-term social housing on biconditional association task performance and neuron ensembles in the anterior cingulate cortex and the hippocampal CA3 region of aged rats."

9 Oct 2025

Nasal spray of gold nanoparticles delivers lithium directly to the brain

In the form of a 'nasal spray', tiny gold particles act as carriers, delivering a treatment directly to the brain: developed by scientists at the Università Cattolica Rome campus/Fondazione Policlinico Universitario A. Gemelli IRCCS, a new nanotechnological device for the treatment and prevention of neuropsychiatric and neurodegenerative diseases.

8 Oct 2025

UCSF and Allen Institute create most detailed data-driven map of the mouse brain

In a powerful fusion of AI and neuroscience, researchers at the University of California, San Francisco (UCSF) and Allen Institute designed an AI model that has created one of the most detailed maps of the mouse brain to date, featuring 1,300 regions/subregions.

7 Oct 2025

Study links brain waves to misremembering of negative, irrelevant information

A good night's sleep has long been understood to help us consolidate new memories, but we don't understand how. Associations with negative feelings like fear or stress can improve recall, but intentionally trying to remember can also be effective. But these two mechanisms are very different - one involuntary, one deliberate.

7 Oct 2025

The World Vaccine Congress heads to Amsterdam, where it will draw experts and leaders from science, academia, start-ups, biotechnology and pharmaceutical companies making this event Europe’s most attractive R&D conference

Sessions will cover topics from Clinical Development to Bioprocessing & Manufacturing to Cancer Immunotherapy and much more.

From World Vaccine Congress Europe 2 Oct 2025

New AI system streamlines segmentation of biomedical images

Annotating regions of interest in medical images, a process known as segmentation, is often one of the first steps clinical researchers take when running a new study involving biomedical images.

26 Sep 2025

New research links postictal symptoms in epilepsy to hidden brain waves

In everyday clinical practice, symptoms are regularly observed after epileptic seizures, known as "post-ictal symptoms", which, in contrast to the usually short duration of seizures, typically last several minutes to hours. Besides symptoms such as impaired speech and language comprehension, a state of disorientation may occur.

19 Sep 2025

Researchers identify seizure-associated depolarization as cause of post-ictal symptoms

People with temporal lobe epilepsy in particular often wander around aimlessly and unconsciously after a seizure. Researchers at the University Hospital Bonn (UKB), the University of Bonn, and the German Center for Neurodegenerative Diseases (DZNE) have identified a neurobiological mechanism that could be responsible for this so-called post-ictal wandering and potentially other postictal symptoms.

18 Sep 2025

Tai chi improves memory and sleep in older adults with type 2 diabetes

A 12-week randomized trial found that remotely delivered Tai Chi significantly enhanced cognitive performance and sleep quality in older adults with Type 2 Diabetes. These gains surpassed those from supervised fitness walking or usual care, without increasing adverse events.

17 Sep 2025

Study uncovers how the brain flexibly switches communication routes

When we recall something familiar or explore a new situation, the brain does not always use the same communication routes.

16 Sep 2025

Infection or stressful events during pregnancy may increase anxiety risk in offspring

Increased risk for anxiety may begin before birth, shaped by infection or stressful events during pregnancy, according to a new preclinical study from researchers at Weill Cornell Medicine.

11 Sep 2025

Can video game–style exercise slow Alzheimer’s risk?

Gamified exercise training improves hippocampal volume and cognitive performance in mild neurocognitive disorders, offering potential for dementia prevention.

10 Sep 2025

Experts review the evidence on coenzyme Q10 and cognitive decline

Researchers reviewed evidence on coenzyme Q10 (CoQ10) and cognition, finding strong biological support and positive results in animal models but mixed outcomes in human trials. Larger, high-quality studies are needed to clarify whether CoQ10 can protect against cognitive decline and neurodegenerative diseases.

9 Sep 2025

Berberine improves cognitive function in diabetic encephalopathy mice

A recent study published in Engineering has shed new light on the potential therapeutic effects of berberine (BBR), a natural compound derived from traditional Chinese medicine, in treating diabetic encephalopathy (DE).

9 Sep 2025

Study reveals electrophysiological signals associated with extinction of aversive memories in humans

Suppression of fear-related memories after unpleasant experiences is very critical for adaptive behavior, as it allows one to inhibit responses that could lead to psychiatric problems such as anxiety or depression.

5 Sep 2025

Understanding the role of paraventricular thalamic nucleus in bipolar disorder pathophysiology

Bipolar disorder (BD) is a chronic mental health condition characterized by recurrent episodes of depression and mania.

4 Sep 2025

Smell loss emerges as the early behavioural sign of Alzheimer’s

Research reveals immune cells target brainstem nerves, linking smell loss to early Alzheimer's, offering potential for earlier diagnosis and intervention.

4 Sep 2025

Epigenomic erosion linked to cognitive decline in Alzheimer’s patients

Most people recognize Alzheimer's from its devastating symptoms such as memory loss, while new drugs target pathological aspects of disease manifestations, such as plaques of amyloid proteins.

2 Sep 2025

New insights into early brain circuit breakdown in Alzheimer’s

One of the first parts of the brain affected by Alzheimer's disease is the entorhinal cortex - a region that plays a big role in memory, spatial navigation, and the brain's internal mapping system.

2 Sep 2025

Breathwork may mimic psychedelic effects through brain changes

Breathwork while listening to music may induce a blissful state in practitioners, accompanied by changes in blood flow to emotion-processing brain regions, according to a study published August 27, 2025, in the open-access journal PLOS One by Amy Amla Kartar from the Colasanti Lab in the Department of Clinical Neuroscience at Brighton and Sussex Medical School, U.K., and colleagues.

28 Aug 2025