Metabolite News and Research

RSS

Metabolites are the intermediates and products of metabolism. The term ''metabolite'' is usually restricted to small molecules.

Researchers provide new insights into how exercise helps lose weight

Researchers at Baylor College of Medicine, Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital, Stanford University School of Medicine and collaborating institutions provide new insights into how exercise helps lose weight.

16 Sep 2025

How processed red meat might drive neurodegenerative diseases

The relationship between processed red meat and neurodegenerative diseases is complex, with potential risks and protective effects requiring more investigation.

15 Sep 2025

Keto diet reduces depression symptoms by 70% in college students

Research indicates a ketogenic diet may serve as an effective adjunct therapy for major depression in college students, improving mood and cognitive abilities.

15 Sep 2025

Novel vitamin K analogs show promise for reversing neurodegenerative diseases

Neurodegenerative diseases like Alzheimer's, Parkinson's, and Huntington's disease are characterized by the progressive loss of neurons.

13 Sep 2025

Genetic mutation in some East Asians linked to aldehyde storm and increased liver disease risk

Researchers have identified the mechanism by which a common genetic mutation increases liver disease risk. Their findings suggest that healthy choices, such as increasing antioxidants and limiting exposure to smoke, may reduce the risk of this disease.

13 Sep 2025

Can cannabis use disrupt women’s fertility? New study finds strong evidence

Researchers found that THC, the psychoactive compound in cannabis, alters oocyte gene expression, spindle formation, and chromosome segregation, lowering embryo euploidy rates in IVF. This provides direct human evidence linking cannabis exposure to impaired female fertility outcomes.

10 Sep 2025

Berberine improves cognitive function in diabetic encephalopathy mice

A recent study published in Engineering has shed new light on the potential therapeutic effects of berberine (BBR), a natural compound derived from traditional Chinese medicine, in treating diabetic encephalopathy (DE).

9 Sep 2025

Study identifies a reductive uric acid degradation pathway in anaerobic bacteria

Uric acid builds up in the blood when the body cannot excrete it efficiently, leading to painful gout attacks, kidney stones, and other complications.

8 Sep 2025

Can cereal microgreens become the next sustainable superfood?

Rich in vitamins and minerals, cereal microgreens offer superior nutritional benefits over mature grains, supporting health and addressing dietary deficiencies.

5 Sep 2025

How plant compounds could target Alzheimer’s disease from multiple angles

This review highlights how dietary polyphenols modulate Alzheimer’s disease biology through antioxidant, anti-inflammatory, and multi-target mechanisms, supported by in-silico docking analyses. Despite promise, challenges in bioavailability and brain delivery remain key hurdles to clinical translation.

31 Aug 2025

Ultra-processed foods affect sperm quality and metabolism even without extra calories

A controlled crossover trial in Cell Metabolism found that ultra-processed foods increase weight, fat mass, LDL:HDL cholesterol, and alter reproductive hormones in men, with some effects independent of calorie load. These diets also showed trends toward reduced sperm motility, shifts in pollutants, and transient inflammatory responses, highlighting risks beyond excess calories.

31 Aug 2025

Alzheimer’s research uncovers a new therapeutic pathway for the memory-robbing malady

The gut contains the largest collection of immune cells in the body. New research at the Buck Institute shows that some of those immune cells travel along the brain/gut axis in a mouse model of Alzheimer's disease (AD) providing a potential new therapeutic pathway for the memory-robbing malady.

29 Aug 2025

Probiotic enhances cholesterol drug efficacy but raises safety concerns at high doses

A recent study published in Engineering has shed light on the complex interactions between probiotics and drugs, particularly focusing on the effects of the probiotic Lacticaseibacillus paracasei Zhang (LCZ) on the cholesterol-lowering drug lovastatin.

28 Aug 2025

High protein diet linked to increased risk of cancer-associated venous thromboembolism

Next to cancer recurrence or progression, cardiovascular diseases are the leading causes of death in cancer survivors.

28 Aug 2025

Can the gut microbiome adapt to protect the brain after stroke?

Alterations in gut microbiota post-stroke may drive metabolic changes, presenting opportunities for innovative therapeutic strategies in acute stroke recovery.

28 Aug 2025

Mediterranean diet lowers dementia risk by altering key metabolites

Researchers linked genetics, plasma metabolites, and Mediterranean diet adherence to dementia risk in two large US cohorts, showing APOE4 homozygotes had distinct metabolic pathways. Diet-related metabolites mediated protection, highlighting precision-prevention opportunities.

26 Aug 2025