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Ultra-long protein fibrils are a signature of severe Alzheimer’s disease, study shows

During the course of Alzheimer's disease, protein fibrils appear in the spinal fluid of affected individuals. Empa researchers, together with the Department of Neurology at the Cantonal Hospital in St. Gallen, have now visualized the wide spectrum of protein aggregates from oligomers, protofibrils to fibrils in the spinal fluid.

9 May 2023

Powerful two-photon microscopy for imaging fast biological processes

Two-photon microscopy (TPM) has revolutionized the field of biology by enabling researchers to observe complex biological processes in living tissues at high resolution.

4 May 2023

Researchers develop a deep learning model to classify cancer cells by type

Cancer cells that initiate metastasis, or the spread of the disease from its primary location, are different from cancer cells that stay in the original tumor. Distinguishing metastasis-initiating cell types can determine the severity of cancer and help medical practitioners decide on a course of treatment.

2 May 2023

Unraveling Nature's Complexity with Molecular Imaging

In this interview conducted at Pittcon 2023 in Philadelphia, Pennsylvania, we spoke to Ron Heeran, a speaker at the 2023 James L. Waters Symposium.

From Pittcon 1 May 2023

Bourn Hall offers ‘at-home’ semen analysis service to reduce male embarrassment

Male embarrassment over the thought of giving a semen sample at a clinic can delay couples getting the fertility support they need. To overcome this issue, fertility clinic Bourn Hall is offering a service where a sample produced at home is collected for rapid analysis, and the results explained one-to-one by a specialist fertility consultant.

29 Apr 2023

Testing hundreds of existing therapeutics to fight blood cancer more effectively

Multiple myeloma is a rare blood cancer caused by the uncontrolled multiplication of abnormal plasma cells.

27 Apr 2023

Study reveals the mechanism behind oligomeric assembly of a BAR-domain-containing protein

Cell membranes play a critical role by serving as containment units and separating the inner cellular space from the extracellular environment.

26 Apr 2023

Bee venom nanoparticles: Buzzworthy breakthrough in battling antibiotic-resistant bacteria

Study aimed to test the antibacterial and cytotoxic effects of bee venom-loaded chitosan nanoparticles (BV-loaded CS-NPs) against Staphylococcus aureus. The results showed that BV-loaded CS-NPs had enhanced antibacterial activity and minimal cytotoxicity, making it a promising antibiotic alternative.

24 Apr 2023

Microplastics: How safe are factory workers from invisible threats?

Researchers examine exposure to microplastics in plastic factory personnel.

24 Apr 2023

New and efficient technique for rapid antibiotic susceptibility testing using optical microscopy

Researchers at EPFL and Vrije Universiteit Brussel have developed a novel and highly efficient method for rapid antibiotic susceptibility testing using optical microscopy.

24 Apr 2023

Study reveals a previously unknown mechanism for DNA folding

A hitherto unknown mechanism for DNA folding is described in a study in Nature published by researchers from Karolinska Institutet and the Max Planck Institute for Biophysics.

19 Apr 2023

Researchers discover the molecule responsible for guiding T cells toward tumors

Immunotherapy, particularly CAR T-Cell treatment for cancer, is extending the lives of many patients. But sometimes the therapy randomly migrates to places it shouldn't go, tucking into the lungs or other noncancerous tissue and causing toxic side effects.

18 Apr 2023

Light-activated SpyLigation can turn on proteins both inside and outside of living cells

Scientists can now use light to activate protein functions both inside and outside of living cells. The new method, called light-activated SpyLigation, can turn on proteins that are normally off to allow researchers to study and control them in more detail.

18 Apr 2023

The Parkinson's Pandemic: from the importance of early diagnosis to digital solutions

News Medical spoke to Michele Hu, Consultant Neurologist at Oxford University Hospitals and Professor of Clinical Neuroscience at the Nuffield Department of Clinical Neurosciences, University of Oxford, about prodromal Parkinson's and what the future looks like for this neurological disease.

11 Apr 2023

BU researcher receives $1.5 million NIH grant to purchase state-of-the-art cryo-EM

Esther Bullitt, PhD, associate professor of pharmacology, physiology & biophysics at Boston University Chobanian & Avedisian School of Medicine, was awarded $1.5 million from the National Institutes of Health that will go toward the purchase of a cryogenic electron microscope.

10 Apr 2023

Creation of embryo-like structures from monkey embryonic stem cells for the first time

Human embryo development and early organ formation remain largely unexplored due to ethical issues surrounding the use of embryos for research as well as limited availability of materials to study.

6 Apr 2023

Some bacteria cells get hangry too, study finds

Have you ever been so hungry that you become angry, otherwise known as "hangry?" New research by Adam Rosenthal, PhD, assistant professor in the Department of Microbiology and Immunology, has found that some bacteria cells get hangry too, releasing harmful toxins into our bodies and making us sick.

3 Apr 2023

Next-level technology for making time-released drugs could be a remedy for missed medications

Missing crucial doses of medicines and vaccines could become a thing of the past thanks to Rice University bioengineers' next-level technology for making time-released drugs.

3 Apr 2023

CrestOptics launches CICERO system to provide all-in-one solution for widefield and spinning disk confocal microscopy

CrestOptics S.p.A., a manufacturer of high-end microscopy solutions and advanced systems for fluorescence microscopy and diagnostic applications, today announced the launch of its new spinning disk confocal microscope system, CICERO.

From CrestOptics 3 Apr 2023

Researchers create a visualization of the full-length human BRCA2 protein at single molecule level

Using a self-built inverted microscope complete with laser optical tweezers to capture DNA, Yale Cancer Center and University of California Davis researchers for the first time created a visualization of the full-length human BRCA2 protein at the single molecule level.

31 Mar 2023

Microscope News and Research

Ultra-long protein fibrils are a signature of severe Alzheimer’s disease, study shows

Powerful two-photon microscopy for imaging fast biological processes

Researchers develop a deep learning model to classify cancer cells by type

Unraveling Nature's Complexity with Molecular Imaging

Bourn Hall offers ‘at-home’ semen analysis service to reduce male embarrassment

Testing hundreds of existing therapeutics to fight blood cancer more effectively

Study reveals the mechanism behind oligomeric assembly of a BAR-domain-containing protein

Bee venom nanoparticles: Buzzworthy breakthrough in battling antibiotic-resistant bacteria

Microplastics: How safe are factory workers from invisible threats?

New and efficient technique for rapid antibiotic susceptibility testing using optical microscopy

Study reveals a previously unknown mechanism for DNA folding

Researchers discover the molecule responsible for guiding T cells toward tumors

Light-activated SpyLigation can turn on proteins both inside and outside of living cells

The Parkinson's Pandemic: from the importance of early diagnosis to digital solutions

BU researcher receives $1.5 million NIH grant to purchase state-of-the-art cryo-EM

Creation of embryo-like structures from monkey embryonic stem cells for the first time

Some bacteria cells get hangry too, study finds

Next-level technology for making time-released drugs could be a remedy for missed medications

CrestOptics launches CICERO system to provide all-in-one solution for widefield and spinning disk confocal microscopy

Researchers create a visualization of the full-length human BRCA2 protein at single molecule level

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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