Ophthalmology News and Research

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Ophthalmology is the specialized field of medicine that focuses on the health of the eye. It includes the anatomy, physiology and diseases that may affect the eye. Historically, the science of ophthalmology encompassed all aspects of visual function, both in health and in illness. Additionally, ophthalmology also includes animal eyes as ocular function and optic diseases are similar among humans and animals.

The business of clinical trials is booming. Private equity has taken notice.

After finding success investing in the more obviously lucrative corners of American medicine — like surgery centers and dermatology practices — private equity firms have moved aggressively into the industry's more hidden niches: They are pouring billions into the business of clinical drug trials.

2 Dec 2022

Newly identified genetic mutation may be a root cause of severe childhood glaucoma

An international team of scientists led by Mass Eye and Ear, a member of Mass General Brigham, and Boston Children's Hospital, has discovered a new genetic mutation that may be a root cause of severe cases of childhood glaucoma, a devastating condition that runs in families and can rob children of their vision by 3 years of age.

1 Dec 2022

Study compares the performance of two most popular AMD drugs

A pilot, "look-back" study of information about 106 patients with "wet" age-related macular degeneration (AMD) treated at the Wilmer Eye Institute at Johns Hopkins Medicine has revealed that nearly half of patients treated with aflibercept could safely stop eye injection therapy after one year without further vision loss.

30 Nov 2022

INPP5D gene plays key role in enabling microglial cells to prevent plaque buildup

A change in the DNA code (mutation) of a gene that plays a key role in the brain's immune defenses may prevent related cells from clearing away protein-filled clumps, a new study in mice shows.

30 Nov 2022

Research findings may offer a new potential therapeutic target for Alzheimer’s disease

A new study links a gene concentrated in the brain's cleanup cells, known as microglia, to the inflammation that has increasingly emerged as a key mechanism contributing to Alzheimer's disease.

30 Nov 2022

Endogenous system may be responsible for delayed onset of diabetic retinopathy

About one third of patients with diabetes mellitus (DM) develop diabetic retinopathy (DR), a leading cause of blindness in working-age individuals. DR typically develops after many years of DM, and some patients do not develop DR for more than 50 years.

29 Nov 2022

Low-dose CT screening improves survival rate of lung cancer patients

Diagnosing early-stage lung cancer with low-dose computed tomography (CT) screening drastically improves the survival rate of cancer patients over a 20-year period, according to a large-scale international study being presented by Mount Sinai researchers at the annual meeting of the Radiological Society of North America.

22 Nov 2022

Repetitive stress induces features of accelerated aging in the eye

New research from the University of California, Irvine, suggests aging is an important component of retinal ganglion cell death in glaucoma, and that novel pathways can be targeted when designing new treatments for glaucoma patients.

21 Nov 2022

Sick profit: Investigating private equity’s stealthy takeover of health care across cities and specialties

Two-year-old Zion Gastelum died just days after dentists performed root canals and put crowns on six baby teeth at a clinic affiliated with a private equity firm.

14 Nov 2022

Researchers trace the origin of Japan’s traditional Kampo medicines

Traditional Chinese medicine (TCM) has been around for centuries. With a history of almost 3000 years dating back to the early Zhou Dynasty, it has been incorporated into China's present medical system.

11 Nov 2022

Study helps understand the basis of sex differences in SARS-CoV-2 infection

Significant immunological differences between young men and women were shown to mediate sex differences in the responses to the virus that causes COVID-19, according to a collaborative study of nearly 3,000 young, healthy members of the U.S. Marine Corps.

8 Nov 2022

Lower hydroxychloroquine dosing results in increased SLE-related hospitalizations, study finds

New research presented this week at ACR Convergence 2022, the American College of Rheumatology's annual scientific meeting, found that the recommended weight-based or non-weight-based dose of hydroxychloroquine led to more hospitalizations for flares among patients with systemic lupus erythematosus

8 Nov 2022

Researchers identify therapies for multiple myeloma patients whose cancer relapses after CAR-T

Mount Sinai and Memorial Sloan Kettering Cancer Center (MSK) researchers have identified therapies that can help patients with the blood cancer multiple myeloma who try an immunotherapy known as CAR-T only to find their cancer coming back afterwards.

4 Nov 2022

Sophisticated tool helps measure exposure levels to PFAS

A novel metric that estimates our "burden," or cumulative exposure, to a family of thousands of synthetic chemicals that we encounter in everyday life with potentially adverse health impacts, has been created by a team of researchers at Mount Sinai.

2 Nov 2022

Study provides more nuanced insights into RNA modifications by A-to-I editing during brain development

Mount Sinai researchers have cataloged thousands of sites in the brain where RNA is modified throughout the human lifespan in a process known as adenosine-to-inosine (A-to-I) editing, offering important new avenues for understanding the cellular and molecular mechanisms of brain development and how they factor into both health and disease.

1 Nov 2022

BCRF renews funding to support the development of novel therapeutics for triple-negative breast cancer

The Breast Cancer Research Foundation (BCRF) has renewed its funding to Elisa Port, MD, and Hanna Irie, MD, PhD, to study new therapeutic approaches that target aggressive triple-negative breast cancer.

31 Oct 2022

Study finds persistent disparities in access to prenatal care among pregnant people

Immigrant pregnant people faced persistent inequities in obtaining timely prenatal care as compared with native-born pregnant people in the United States over an eight-year period, a factor that could be contributing to longstanding health disadvantages, according to an analysis published in JAMA Network Open on October 28.

28 Oct 2022

Study sheds light on why some patients respond better than others to immunotherapy

Immunotherapy, a biotherapy that boosts the ability of the immune system to recognize and attack mutant tumor cells, has transformed the treatment landscape for patients battling cancer, which emerges from the progressive accumulation of DNA mutations.

27 Oct 2022

Scientific Grand Prize awarded to renowned hearing loss researcher

M. Charles Liberman, PhD, whose research forever changed the way experts understand the underlying causes of hearing loss, has been awarded the Scientific Grand Prize from the France-based La Fondation Pour l'Audition.

21 Oct 2022

Researchers identify a new gene essential to colon cancer growth

Researchers at Mount Sinai's Tisch Cancer Institute have identified a new gene that is essential to colon cancer growth and found that inflammation in the external environment around the tumor can contribute to the growth of tumor cells.

17 Oct 2022

Ophthalmology News and Research

Further Reading

The business of clinical trials is booming. Private equity has taken notice.

Newly identified genetic mutation may be a root cause of severe childhood glaucoma

Study compares the performance of two most popular AMD drugs

INPP5D gene plays key role in enabling microglial cells to prevent plaque buildup

Research findings may offer a new potential therapeutic target for Alzheimer’s disease

Endogenous system may be responsible for delayed onset of diabetic retinopathy

Low-dose CT screening improves survival rate of lung cancer patients

Repetitive stress induces features of accelerated aging in the eye

Sick profit: Investigating private equity’s stealthy takeover of health care across cities and specialties

Researchers trace the origin of Japan’s traditional Kampo medicines

Study helps understand the basis of sex differences in SARS-CoV-2 infection

Lower hydroxychloroquine dosing results in increased SLE-related hospitalizations, study finds

Researchers identify therapies for multiple myeloma patients whose cancer relapses after CAR-T

Sophisticated tool helps measure exposure levels to PFAS

Study provides more nuanced insights into RNA modifications by A-to-I editing during brain development

BCRF renews funding to support the development of novel therapeutics for triple-negative breast cancer

Study finds persistent disparities in access to prenatal care among pregnant people

Study sheds light on why some patients respond better than others to immunotherapy

Scientific Grand Prize awarded to renowned hearing loss researcher

Researchers identify a new gene essential to colon cancer growth

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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