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The Proteoform Puzzle: Unlocking the Next Frontier

In the interview, Lloyd M. Smith discusses proteoforms, an area of research worthy of the next Human Genome Project.

From Pittcon 10 Jul 2025

AI tool outperforms existing methods in diagnosing cardiac amyloidosis

In a new study published in the European Heart Journal, researchers reported the successful development and validation of a medical artificial intelligence (AI) model that screens for cardiac amyloidosis, a progressive and irreversible type of heart disease.

9 Jul 2025

Researchers use cryo-EM to map Powassan virus structure at high resolution

As summer kicks into full gear and people are spending more time outside, there's one thing on many people's minds - ticks.

9 Jul 2025

Athletes across sports share core movement efficiencies

New research into the muscles of world-class athletes and performance artists has revealed that a small number of "general motor skills" raise these experts above regional-level and novice competitors, with interesting implications for competitive sport and musculoskeletal health.

9 Jul 2025

Fluorescent-guided nerve imaging agent shows promise for use in humans

For the first time, a fluorescent-guided nerve imaging agent shows promise for use in humans, according to a paper published in Nature Communications.

9 Jul 2025

FDA-approved drugs can help enhance the safety of nanomedicines

An international study led by researchers at the University of Colorado Anschutz Medical Campus has identified a promising strategy to enhance the safety of nanomedicines, advanced therapies often used in cancer and vaccine treatments, by using drugs already approved by the FDA for unrelated conditions.

9 Jul 2025

MIT develops implantable device to automatically release emergency glucagon

For people with Type 1 diabetes, developing hypoglycemia, or low blood sugar, is an ever-present threat. When glucose levels become extremely low, it creates a life-threatening situation for which the standard treatment of care is injecting a hormone called glucagon.

9 Jul 2025

Mapping vulnerability or resilience in Alzheimer's through imaging and genetics

It's been recognized for some time that Alzheimer's disease affects brain regions differently and that tau - a protein known to misbehave - plays an important role in the disease.

9 Jul 2025

Artificial intelligence tracks aging and damaged cells through high resolution imaging

A combination of high-resolution imaging and machine learning, also known as artificial intelligence (AI), can track cells damaged from injury, aging, or disease, and that no longer grow and reproduce normally, a new study shows.

8 Jul 2025

Artificial intelligence enhances radiologists’ accuracy in breast cancer detection

Artificial intelligence (AI) improves breast cancer detection accuracy for radiologists when reading screening mammograms, helping them devote more of their attention to suspicious areas, according to a study published today in Radiology, a journal of the Radiological Society of North America.

8 Jul 2025

Shaping the future of psychiatry with precision medicine

In a comprehensive Genomic Press Interview published today in Genomic Psychiatry, Dr. Mirko Manchia opens up about his transformative journey from a small Sardinian city to becoming a leading voice in psychiatric pharmacogenomics, revealing how personal family experiences with mental illness sparked a lifelong quest to understand why psychiatric medications work brilliantly for some patients while failing others.

8 Jul 2025

Scientists uncover hidden superfamily of lipid trapping proteins in bacteria

Scientists have identified a new type of protein in bacteria that could change our understanding of how these organisms interact with their environments.

8 Jul 2025

Astrocytes influence metabolism and cognitive function in obesity

Fatty diets and obesity affect the structure and function of astrocytes, the star-shaped brain cells located in the striatum, a brain region involved in the perception of pleasure generated by food consumption.

7 Jul 2025

Multifunctional nanodisk enables cancer diagnosis, treatment and immune activation

The Korea Research Institute of Standards and Science (KRISS, President Lee Ho Seong) has successfully developed a nanomaterial capable of simultaneously performing cancer diagnosis, treatment, and immune response induction.

7 Jul 2025

Amino acid metabolism in breast cancer as a driver of disease and therapeutic target

The review introduces the molecular subtypes of breast cancer and outlines how altered amino acid metabolism supports tumor growth.

7 Jul 2025

Fluorescent drug helps surgeons see nerves clearly during complex procedures

When surgeons dissect tissue to remove a tumor or make a repair they must work cautiously, relying on electrophysical monitors and their own anatomical knowledge to avoid cutting nerves, which could complicate the patient's recovery.

4 Jul 2025

Real time imaging reveals how visual experience rewires the brain

Scientists have long known that the brain's visual system isn't fully hardwired from the start-it becomes refined by what babies see-but the authors of a new MIT study still weren't prepared for the degree of rewiring they observed when they took a first-ever look at the process in mice as it happened in real-time.

4 Jul 2025