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Innovative nanopore system enables controlled DNA unzipping

DNA holds the instructions that make us who we are. If we want to read those instructions, say to understand our predisposition to genetic disorders, we need to carefully 'unzip' DNA's iconic double-helix structure.

30 Jul 2025

New platform predicts antibiotic resistance before it hits the clinics

Multidrug resistant bacteria kill five million people each year, with newly resistant germs emerging faster than scientists can develop treatments.

30 Jul 2025

New genetic mutation linked to highly invasive Streptococcus pyogenes infections

A group of researchers led by The University of Osaka have identified a novel genetic mutation in Streptococcus pyogenes, a common bacterium which causes strep throat, significantly associated with severe invasive infections.

30 Jul 2025

Tiny artificial cells successfully mimic biological clocks

A team of UC Merced researchers has shown that tiny artificial cells can accurately keep time, mimicking the daily rhythms found in living organisms.

29 Jul 2025

New RNA therapy reverses symptoms of progeria in mouse models

Children who develop deep wrinkles, stunted growth, and rapidly aging bones and blood vessels as early as 1 to 2 years of age may be suffering from Hutchinson-Gilford Progeria Syndrome (HGPS), a rare and incurable genetic disorder that affects approximately one in eight million people.

29 Jul 2025

NR2F1 drives fibrotic cataract formation through activation of STAT3

Cataracts remain one of the most prevalent and debilitating eye conditions, often requiring surgical intervention to restore sight. Yet even after surgery, many patients develop anterior subcapsular cataracts (ASC), characterized by fibrotic tissue growth beneath the lens capsule.

29 Jul 2025

Pyruvate identified as a promising oral treatment for ulcerative colitis

Ulcerative colitis (UC) is a chronic inflammatory disease marked by intestinal pain, bleeding, and impaired gut barrier function.

29 Jul 2025

NKAPL identified as a tumor suppressor and therapeutic target in NSCLC

Non-small cell lung cancer (NSCLC) accounts for over 80% of lung cancer cases and is often diagnosed at advanced stages, limiting treatment options.

29 Jul 2025

Immunotherapy shows promise in changing leukemia’s cellular environment

Scientists studying a hard-to-treat form of blood cancer called acute myeloid leukemia (AML) have found that a type of treatment - immunotherapy - may help change the environment where cancer cells live, possibly helping the immune system respond more effectively.

29 Jul 2025

Groundbreaking Living Brain Project challenges decades of assumptions in neuroscience

In a revealing Genomic Press Interview published today in Genomic Psychiatry, Dr. Alexander W. Charney describes how treating patients with schizophrenia transformed his scientific pursuits from abstract questions to an urgent mission, ultimately leading to discoveries that challenge fundamental assumptions in neuroscience research.

29 Jul 2025

Gut mycobiota could help predict disability in multiple sclerosis

Gut fungal communities may impact multiple sclerosis severity, offering new insights into MS pathogenesis and potential microbiome-based treatment strategies.

29 Jul 2025

New research links age-related gene changes to symptom decline

UCSF researchers have found that certain antiviral genes become less active over time in lupus, revealing why some patients see their symptoms fade as they age.

29 Jul 2025

Brain’s blood vessels and immune cells play key role in Alzheimer’s and stroke

The brain's health depends on more than just its neurons. A complex network of blood vessels and immune cells acts as the brain's dedicated guardians-controlling what enters, cleaning up waste, and protecting it from threats by forming the blood-brain barrier.

28 Jul 2025

Restoring mitochondria enhances immune response against lung cancer

While chemotherapy remains a cornerstone of lung cancer treatment, it often weakens the immune system it relies on for long-term control.

28 Jul 2025

TraMA offers breakthrough in measuring biological age

A new research paper was published in Aging (Aging-US) Volume 17, Issue 6, on June 13, 2025, titled "Development of a novel transcriptomic measure of aging: Transcriptomic Mortality-risk Age (TraMA)."

28 Jul 2025

Advancing precision medicine in colorectal cancer with multi-omics approaches

Colorectal cancer is among the most prevalent and lethal malignancies worldwide, with liver metastases occurring in nearly one-third of patients and accounting for a major share of cancer-related deaths.

28 Jul 2025

Largest genetic study confirms biological basis of stuttering

The largest genetic analysis of stuttering has demonstrated a clear genetic basis for the speech disorder, highlighting neurological pathways of risk.

28 Jul 2025

Australian scientists uncover new way to halt aggressive cancer growth

Australian researchers have discovered a promising new strategy to suppress the growth of aggressive and hard-to-treat cancers by targeting a specialized molecular process known as 'minor splicing'.

28 Jul 2025

Uncovering origins of autism, depression, Parkinson's in fetal brain

The origin of some neuropsychiatric diseases, such as autism, bipolar disorder, or depression, and certain neurodegenerative diseases, Alzheimer's and Parkinson's, can be found in very early stages of brain formation in the fetus. That is, earlier than previously recognized, according to a study by the Hospital del Mar Research Institute and Yale University, published in Nature Communications.

26 Jul 2025

New research identifies critical gene for ALS treatment

Amyotrophic lateral sclerosis (ALS) - which you may know as the disease that affected Stephen Hawking - is a fatal neurodegenerative disease that causes progressive muscle weakness. A research team at Tohoku University and Keio University has uncovered a unifying mechanism in ALS revolving around the expression of UNC13A (a gene crucial for neuronal communication) that represents a common target for developing effective treatment strategies that could improve the lives of patients with ALS.

26 Jul 2025