Enzyme News and Research

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Novel vaccine against Lyme disease reported to be safe and effective

Researchers determine the safety and immunogenicity of a novel candidate vaccine against Lyme borreliosis.

11 Jul 2023

The causative role of age-associated pre-existing senescent cells on COVID-19 severity

Researchers investigated the role of senescent cells in the context of SARS-CoV-2 infection.

10 Jul 2023

Prolonged T-cell response during severe COVID-19 does not contribute to long COVID

Persistent immune activation and elevated cytokine levels were observed in patients with severe COVID-19, even months after recovery. However, the correlation between immune activation and long COVID symptoms appeared to be independent, suggesting other factors influencing disease severity.

9 Jul 2023

Researchers identify an enzyme that plays a critical role in the late stages of HIV replication

Researchers at Johns Hopkins Medicine, in collaboration with researchers at the National Institutes of Health, report that two new studies in mice with a humanized immune system and human cell lines have identified an enzyme that plays a critical role in the late stages of HIV replication.

6 Jul 2023

Scientists develop breakthrough approach to create artificial allosteric sites in protein complexes

According to a recently published research paper by a team of scientists, a groundbreaking approach has been developed to create artificial allosteric sites (where by binding an effector molecule, activity at the distal active site is regulated) in protein complexes.

6 Jul 2023

Unlocking the immune puzzle: study evaluates the immune impact of second booster COVID-19 vaccine

Researchers assessed acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant of concern (VOC).

6 Jul 2023

Rising incidence of kiwifruit allergy in children: study highlights severe allergic reactions

Study aimed to compile Kiwifruit allergy recognition patterns to enhance patient management and clinical practice.

6 Jul 2023

Danish researchers solve puzzle of how hepatitis C virus evades immune system

With a new method for examining virus samples researchers from the University of Copenhagen have solved an old riddle about how Hepatitis C virus avoids the human body's immune defenses.

5 Jul 2023

Researchers uncover the role of glutaminase 2 in glucose homeostasis

Glutaminase 2 (GLS2) is a master regulator of glutaminolysis. GLS2 converts glutamine to glutamate, thereby playing a role in cellular energy production. GLS2 is abundant in the liver, and is also found in pancreatic β-cells. However, the role of GLS2 in pancreatic islets – in which both ɑ- and β- cells are present – associated with glucose metabolism is currently unknown.

5 Jul 2023

Beyond the lungs: SARS-CoV-2's multi-organ impact revealed

Researchers present the mechanisms by which SARS-CoV-2 could infect the brain and affect memory.

5 Jul 2023

A novel RSV vaccine that could be effective across all ages

Researchers evaluate the in vivo efficacy of a respiratory syncytial virus vaccine in old and young rats.

4 Jul 2023

Was there a change in the incidence of diabetes in children and adolescents after the onset of the COVID-19 pandemic?

Study compares the incidence rates of pediatric T1D and 2D during and before SARS-CoV-2.

4 Jul 2023

Mutations in AGC kinase motif linked to colorectal cancer growth

Cancer spreads throughout the human body in cunning, almost militaristic, ways. For example, it can manipulate our genetic make-up, take over specific cell-to-cell signaling processes, and mutate key enzymes to promote tumor growth, resist therapies, and hasten its spread from the original site to the bloodstream or other organs.

3 Jul 2023

AI predicts on- and off-target activity of RNA-targeting CRISPRs

Artificial intelligence can predict on- and off-target activity of CRISPR tools that target RNA instead of DNA, according to new research published in Nature Biotechnology.

3 Jul 2023

Cell therapy using genome-edited iPS cells could be a new treatment for Fabry disease

Induced pluripotent stem (iPS) cells have a great impact on biology and medicine, and they are expected to improve regenerative medicine.

3 Jul 2023

Camena Bioscience closes $10m Series A financing as demand for DNA synthesis technology increases

Camena Bioscience, a synthetic biology company providing genes to the pharmaceutical and biotechnology industries.

From Camena Bioscience 3 Jul 2023

Study finds that genetically determined milk intake does not increase type-2 diabetes risk

Researchers investigate the association between the genetic basis of milk consumption and type 2 diabetes risk.

3 Jul 2023

COVID-19 severity linked to autoantibodies against blood clotting protein

Study investigates the occurrence of ADAMTS13 antibodies in COVID-19 patients and their association with disease severity and lower ADAMTS13 activity. The findings suggest the need to include ADAMTS13 antibodies in diagnosing and managing SARS-CoV-2 infections.

2 Jul 2023

High-res insights into key bacterial enzyme could lead to development of new antibiotics

A team of scientists from around the globe, including those from Trinity College Dublin, has gained high-res structural insights into a key bacterial enzyme, which may help chemists design new drugs to inhibit it and thus suppress disease-causing bacteria.

30 Jun 2023

Towards Zika preparedness: immunogenicity insights from vaccine research

Study assesses the safety and immunogenicity of an inactivated Zika virus vaccine candidate.

30 Jun 2023

Enzyme News and Research

Novel vaccine against Lyme disease reported to be safe and effective

The causative role of age-associated pre-existing senescent cells on COVID-19 severity

Prolonged T-cell response during severe COVID-19 does not contribute to long COVID

Researchers identify an enzyme that plays a critical role in the late stages of HIV replication

Scientists develop breakthrough approach to create artificial allosteric sites in protein complexes

Unlocking the immune puzzle: study evaluates the immune impact of second booster COVID-19 vaccine

Rising incidence of kiwifruit allergy in children: study highlights severe allergic reactions

Danish researchers solve puzzle of how hepatitis C virus evades immune system

Researchers uncover the role of glutaminase 2 in glucose homeostasis

Beyond the lungs: SARS-CoV-2's multi-organ impact revealed

A novel RSV vaccine that could be effective across all ages

Was there a change in the incidence of diabetes in children and adolescents after the onset of the COVID-19 pandemic?

Mutations in AGC kinase motif linked to colorectal cancer growth

AI predicts on- and off-target activity of RNA-targeting CRISPRs

Cell therapy using genome-edited iPS cells could be a new treatment for Fabry disease

Camena Bioscience closes $10m Series A financing as demand for DNA synthesis technology increases

Study finds that genetically determined milk intake does not increase type-2 diabetes risk

COVID-19 severity linked to autoantibodies against blood clotting protein

High-res insights into key bacterial enzyme could lead to development of new antibiotics

Towards Zika preparedness: immunogenicity insights from vaccine research

Biochemical Assays for Efficient Hit Prioritization After Screening eBook

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Industry Focus eBook - Analytical Chemistry (3rd edition)

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Advancing degrader and proximity-based drug development

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Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo