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SMART researchers awarded NMRC funding to develop rapid paper-based COVID-19 tests

Singapore-MIT Alliance for Research and Technology, MIT's research enterprise in Singapore, has received a grant from the National Medical Research Council COVID-19 Research fund for the acceleration of research and development of rapid paper-based serological and diagnostic tests for COVID-19.

18 May 2020

Novel insights on SARS-CoV-2 cell entry may inform further vaccine and treatment development

A research group from Harvard Medical School reported two cryo-electron microscopy structures derived from a single preparation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein in their paper available on the preprint server bioRxiv. Understanding the nuances of prefusion and postfusion conformations shed light on viral cell entry and may, in turn, guide the development of vaccines and drugs.

18 May 2020

Cigarette smoke spurs the lungs to make more SARS-CoV-2 receptors

New research from CSHL scientists suggests that cigarette smoke spurs the lungs to make more ACE2 (angiotensin-converting enzyme 2), the protein that the coronavirus responsible for COVID-19 grabs and uses to enter human cells.

18 May 2020

Cross-neutralization of SARS and COVID-19 coronaviruses by a monoclonal antibody

An antibody first identified in a blood sample from a patient who recovered from Severe Acute Respiratory Syndrome in 2003 inhibits related coronaviruses, including the cause of COVID-19.

18 May 2020

University of Valencia files patent application for COVID-19 vaccine

The University of Valencia has filed a patent application for a vaccine candidate against COVID-19, developed by a research team from the Department of Microbiology

18 May 2020

"Power-to-protein" approach offers a new way to feed the world's population

Proteins form an essential part of human nutrition. Up to now, we have generally consumed them in meat, animal products such as milk and eggs, or even in plants.

18 May 2020

Climate change threatens prospects for progress in cancer prevention and control

Climate change threatens prospects for further progress in cancer prevention and control, increasing exposure to cancer risk factors and impacting access to cancer care, according to a new commentary by scientists from the American Cancer Society and Harvard T. H. Chan School of Public Health.

18 May 2020

Researchers develop potential drug compound for treating cancer

Researchers at the University of Eastern Finland have developed a new and promising drug compound for the treatment of cancer that inhibits natural amino acids from entering cancer cells.

18 May 2020

Avacta's SARS-COV-2 neutralizing Affimer reagents show therapeutic potential for COVID-19

Avacta Group plc, the developer of Affimer biotherapeutics and reagents, is pleased to announce that several of the Affimer reagents recently generated for development of a point-of-care COVID-19 antigen saliva test have now also been shown to block the interaction between the virus’ spike protein and ACE2, a receptor on human cells that is key to the virus infection pathway.

From Avacta Life Sciences Ltd. 18 May 2020

Boehringer Ingelheim acquires Northern Biologics to expand cancer immunology portfolio

Boehringer Ingelheim today announced the acquisition of Northern Biologics Inc., a wholly owned subsidiary of Northern LP. By acquiring this entity, which focuses on therapeutic antibodies targeting the tumor microenvironment, Boehringer Ingelheim is now positioned at the forefront of the stromal biology space - an emerging area in cancer immunology.

From Boehringer Ingelheim International GmbH 18 May 2020

Research explores how human enzymes could be used to exacerbate COVID-19

Centenary Institute researchers have examined the critical role of human enzymes and the coronavirus in a newly published scientific review article that explores potential strategies for COVID-19 disease treatment and management.

18 May 2020

Oxford University vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques

As the world continues to grapple with the coronavirus pandemic, many scientists, institutions, and pharmaceutical companies are working hard to develop an effective vaccine.

18 May 2020

Kawasaki disease outbreak in children with COVID-19

The ongoing COVID-19 pandemic has marched its way to almost all parts of the world, with hundreds of thousands of deaths and over 4.5 million cases as of May 15, 2020. One saving grace has been the apparent sparing of children, though the mortality in older people is quite high.

17 May 2020

Host-virus interaction drives adaptive mutation in bat CoV related to SARS-CoVs

Virus and receptor diversity is shaped by the need to evolve advanced weaponry to facilitate virus entry and infection, on the one hand, and host resistance, on the other. A new paper published on the preprint server bioRxiv* shows how this mechanism operates in a bat coronavirus, which is related to the earlier SARS coronavirus.

17 May 2020

New and unexplored angle in the binding of SARS-CoV-2 to host cells

Researchers in the Netherlands, Cuba, and Italy have made important discoveries about the carbohydrate-mediated binding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein to host cell lectin receptors and host lung microbiota.

17 May 2020

Well-known cancer drugs may prevent SARS-CoV-2 viral replication say researchers

Researchers in Frankfurt, Germany, have described cell signaling events that occur when severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects host cells and have identified pathways that are essential for the virus to replicate.

17 May 2020

Study shows human monoclonal antibodies can effectively neutralize SARS-CoV-2

US researchers have published a proof of concept on the efficacy of human monoclonal antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in laboratory conditions, as well as their pioneering use in a mouse model. The study is available on the preprint server bioRxiv*.

17 May 2020

Study shows broad geographic and evolutionary dispersal of betacoronaviruses from African bats

A research group from Nigeria found evidence of long-distance transmission and dispersal between bat coronaviruses isolated in Africa and the ones Europe and Asia, as described in a new paper available on the preprint server bioRxiv.

17 May 2020

COVID-19 patients at high risk for developing complications associated with blood clots

When researchers from the University of Colorado Anschutz Medical Campus, Aurora, used a combination of two specific blood-clotting tests, they found critically ill patients infected with Coronavirus Disease 2019 (COVID-19) who were at high risk for developing renal failure, venous blood clots, and other complications associated with blood clots, such as stroke.

15 May 2020

Antiviral drug can help accelerate recovery of COVID-19 patients, study shows

An international team of researchers led by Dr. Eleanor Fish, emerita scientist at the Toronto General Hospital Research Institute, University Health Network, and professor in the University of Toronto's Department of Immunology, has shown for the first time that an antiviral drug can help speed up the recovery of COVID-19 patients.

15 May 2020

Protein C News and Research

SMART researchers awarded NMRC funding to develop rapid paper-based COVID-19 tests

Novel insights on SARS-CoV-2 cell entry may inform further vaccine and treatment development

Cigarette smoke spurs the lungs to make more SARS-CoV-2 receptors

Cross-neutralization of SARS and COVID-19 coronaviruses by a monoclonal antibody

University of Valencia files patent application for COVID-19 vaccine

"Power-to-protein" approach offers a new way to feed the world's population

Climate change threatens prospects for progress in cancer prevention and control

Researchers develop potential drug compound for treating cancer

Avacta's SARS-COV-2 neutralizing Affimer reagents show therapeutic potential for COVID-19

Boehringer Ingelheim acquires Northern Biologics to expand cancer immunology portfolio

Research explores how human enzymes could be used to exacerbate COVID-19

Oxford University vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques

Kawasaki disease outbreak in children with COVID-19

Host-virus interaction drives adaptive mutation in bat CoV related to SARS-CoVs

New and unexplored angle in the binding of SARS-CoV-2 to host cells

Well-known cancer drugs may prevent SARS-CoV-2 viral replication say researchers

Study shows human monoclonal antibodies can effectively neutralize SARS-CoV-2

Study shows broad geographic and evolutionary dispersal of betacoronaviruses from African bats

COVID-19 patients at high risk for developing complications associated with blood clots

Antiviral drug can help accelerate recovery of COVID-19 patients, study shows

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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